CAS 59887-17-1

B-endorfina bovina

Descrizione:

B-endorfina bovina, con il numero CAS 59887-17-1, è un peptide che appartiene alla famiglia delle endorfine, che sono neuropeptidi oppioidi endogeni. È prodotto principalmente nella ghiandola pituitaria e gioca un ruolo cruciale nella modulazione del dolore, nella risposta allo stress e nella regolazione dell'umore. La B-endorfina è composta da 31 aminoacidi ed è nota per la sua capacità di legarsi ai recettori oppioidi nel cervello, portando a effetti analgesici e sensazioni di euforia. Questo peptide è altamente conservato tra le specie, con la B-endorfina bovina simile alla sua controparte umana. In termini di proprietà fisiche, è tipicamente una polvere bianca o bianco sporco solubile in acqua, rendendola adatta per varie applicazioni biochimiche. L'attività biologica della B-endorfina è significativa nella ricerca relativa alla gestione del dolore, alla dipendenza e ai disturbi della salute mentale. La sua stabilità e efficacia possono essere influenzate da fattori come pH e temperatura, che sono considerazioni importanti negli ambienti di laboratorio.

Formula: C₁₅₅H₂₅₀N₄₂O₄₄S

InChI: InChI=1/C155H250N42O44S/c1-17-82(9)123(150(235)182-99(44-29-34-61-160)134(219)186-109(70-116(164)206)139(224)171-84(11)128(213)183-108(69-92-72-166-78-170-92)144(229)178-96(41-26-31-58-157)132(217)175-95(40-25-30-57-156)131(216)169-75-120(210)173-103(155(240)241)51-54-115(163)205)193-151(236)124(83(10)18-2)192-129(214)85(12)172-140(225)110(71-117(165)207)185-133(218)97(42-27-32-59-158)177-143(228)107(68-90-38-23-20-24-39-90)184-141(226)104(64-79(3)4)188-152(237)126(87(14)201)195-149(234)122(81(7)8)191-145(230)105(65-80(5)6)187-148(233)113-45-35-62-197(113)154(239)127(88(15)202)196-137(222)100(50-53-114(162)204)179-146(231)111(76-198)189-135(220)98(43-28-33-60-159)176-136(221)101(52-55-121(211)212)180-147(232)112(77-199)190-153(238)125(86(13)200)194-138(223)102(56-63-242-16)181-142(227)106(67-89-36-21-19-22-37-89)174-119(209)74-167-118(208)73-168-130(215)94(161)66-91-46-48-93(203)49-47-91/h19-24,36-39,46-49,72,78-88,94-113,122-127,198-203H,17-18,25-35,40-45,50-71,73-77,156-161H2,1-16H3,(H2,162,204)(H2,163,205)(H2,164,206)(H2,165,207)(H,166,170)(H,167,208)(H,168,215)(H,169,216)(H,171,224)(H,172,225)(H,173,210)(H,174,209)(H,175,217)(H,176,221)(H,177,228)(H,178,229)(H,179,231)(H,180,232)(H,181,227)(H,182,235)(H,183,213)(H,184,226)(H,185,218)(H,186,219)(H,187,233)(H,188,237)(H,189,220)(H,190,238)(H,191,230)(H,192,214)(H,193,236)(H,194,223)(H,195,234)(H,196,222)(H,211,212)(H,240,241)/t82-,83-,84-,85-,86+,87+,88+,94-,95-,96-,97-,98-,99-,100-,101-,102-,103-,104-,105-,106-,107-,108-,109-,110-,111-,112-,113-,122-,123-,124-,125-,126-,127-/m0/s1

Sinonimi:

• beta-Endorphin (1-31)
• beta-Endorphin, triethoxy(3-isothiocyanatopropyl)-, (6R-(6alpha,7alpha,7(R*)))-

Beta-Endorphin (rat)

CAS: 59887-17-1

Beta-endorphin is a basic protein that is an endogenous opioid peptide hormone with potent analgesic effects. Beta-endorphin binds to the kappa-opioid receptor, which inhibits the production of inflammatory cytokines IL-2 and TNF-α in activated macrophages. Beta-endorphin has been shown to have potent inducers of cardiac contractility and vasodilation when administered intravenously to rats. It also binds to the dextran sulfate receptor and can cause vasoconstriction in rat aorta. In addition, beta-endorphin has been shown to be an inhibitor of pluripotent cells, which are cells that have the ability to differentiate into any type of cell. This inhibition may be due to its binding to basic proteins or its effects on the synthesis of peptide hormones such as prolactin or growth hormone.

Formula: C₁₅₇H₂₅₄N₄₂O₄₄S

Purezza: Min. 95%

Peso molecolare: 3,466.02 g/mol

Ref: 3D-FE108786

Beta-Endorphin (bovine, camel, mouse)

CAS: 59887-17-1

Beta-Endorphin (β-EP) is a peptide hormone that has a number of biological properties. It binds to kappa opioid receptors and affects the function of various cells in the body. β-EP is also potent inducers of pluripotent stem cells and has been shown to reduce pain and inflammation, as well as having anti-inflammatory properties. β-EP may also have some physiological effects on the brain, including increasing blood flow to the brain, affecting memory, and reducing stress levels.

Formula: C₁₅₅H₂₅₀N₄₂O₄₄S

Purezza: Min. 95%

Peso molecolare: 3,437.97 g/mol

Ref: 3D-FE108751

β-Endorphin (bovine, camel, mouse)

CAS: 59887-17-1

Bachem ID: 4007396.

Formula: C₁₅₅H₂₅₀N₄₂O₄₄S

Purezza: 90.8%

Colore e forma: White Powder

Peso molecolare: 3438.01

Ref: 01-4007396