CAS 60-54-8: (-)-Tetraciclina

Descrizione: (-)-Tetraciclina è un antibiotico ad ampio spettro appartenente alla classe delle tetracicline, caratterizzato dalla sua capacità di inibire la sintesi proteica batterica. È derivato dal batterio Streptomyces aureofaciens ed è noto per la sua efficacia contro un'ampia gamma di batteri gram-positivi e gram-negativi. La struttura chimica di (-)-Tetraciclina presenta un sistema a quattro anelli con più gruppi funzionali, inclusi gruppi idrossilici e dimetilamminici, che contribuiscono alla sua solubilità e attività biologica. Questo composto mostra proprietà come una buona biodisponibilità orale e una vita media relativamente lunga, consentendo regimi di trattamento efficaci. (-)-Tetraciclina è anche noto per i suoi potenziali effetti collaterali, tra cui disturbi gastrointestinali e fotosensibilità. Inoltre, è stato utilizzato in varie applicazioni oltre alla medicina umana, inclusa la medicina veterinaria e l'agricoltura, in particolare nel trattamento delle infezioni e come promotore della crescita nel bestiame. Il suo meccanismo d'azione coinvolge principalmente il legame alla subunità ribosomiale 30S, impedendo così l'attacco dell'aminoacil-tRNA e inibendo la sintesi proteica nei batteri.

Formula: C₂₂H₂₄N₂O₈

InChI: InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

InChI key: InChIKey=OFVLGDICTFRJMM-WESIUVDSSA-N

SMILES: O=C(N)C=1C(=O)C2(O)C(O)=C3C(=O)C=4C(O)=CC=CC4C(O)(C)C3CC2C(C1O)N(C)C

Sinonimi:

• (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
• (4S,4aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 6-Methyl-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
• Abramycin
• Achromycin
• Achromycin (naphthacene derivative)
• Acromicina
• Actisite
• Agromicina
• Akne-Pyodron
• Akne-Pyodron Kur
• Ambramicina
• Ambramycin
• Apo-Tetra
• Arcanacycline
• Bio-Tetra
• Biocycline
• Britaciclina
• Calociclina
• Ciclibion
• Cyclomycin
• Cytome
• Deschlorobiomycin
• Dispatetrin
• Economycin
• Enterocycline
• Florocycline
• Gammatet
• Ibicyn
• Kinciclina
• Latycin
• Limecycline
• Medocycline
• Mericycline
• Micycline
• Neocycline
• NorTet
• Novo-Tetra
• Nsc 108579
• Nu-Tetra
• Omegamycin
• Orlycycline
• Panmycin
• Polycycline
• Polycycline (antibiotic)
• Quimocyclin N
• Quimpe Antibiotico
• Resteclin
• Retet
• Robitet Robicaps
• Roviciclina
• Sagittacin N
• Servitet
• Spaciclina
• Steclin V
• Sumycin syrup
• Tetra Hubber
• Tetra-Co
• Tetra-Proter
• Tetrabioptal
• Tetracap
• Tetraciclina
• Tetracitro S
• Tetracyclin
• Tetracycline Base
• Tetracycline Free Base
• Tetradecin
• Tetrafil
• Tetrafosammina
• Tetralan
• Tetralen
• Tetramig
• Tetramykoin
• Tetraseptine
• Triphacycline
• Veracin
• Vetacyclinum

Tetracycline

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈
• Purezza: >95.0%(T)(HPLC)
• Colore e forma: Light yellow to Yellow powder to crystal
• Peso molecolare: 444.44

Tetracycline Hydrochloride

CAS: 60-54-864-75-5

• Formula: C₂₂H₂₄N₂O₈·HCl
• Purezza: >98.0%(T)
• Colore e forma: Light yellow to Amber to Dark green powder to crystal
• Peso molecolare: 480.90

Tetracycline

CAS: 60-54-8

Tetracycline is used for treatment of chronic inflammatory cells. Tetracycline derivatives induce apoptosis in osteoclasts, …

• Formula: C₂₂H₂₄N₂O₈
• Colore e forma: Yellow to orange to brown, Crystalline powder or powder
• Peso molecolare: 444.44

Tetracycline

CAS: 60-54-8

Tetracycline (Tetracyclin) is a broad-spectrum antibiotic. Tetracycline is commonly used in anti-infective studies. Cost-effective and …

• Formula: C₂₂H₂₄N₂O₈
• Purezza: 92.65% - 98.18%
• Colore e forma: Light Yellow Crystal
• Peso molecolare: 444.43

Tetracycline

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈
• Purezza: 96%
• Colore e forma: Solid
• Peso molecolare: 444.4345599999999

Tetracycline, EP grade

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈
• Purezza: 88.0 - 102.0 % (dried basis)
• Colore e forma: Yellow crystalline powder
• Peso molecolare: 444.43

Tetracycline

CAS: 60-54-8

• Purezza: 91.79%
• Peso molecolare: 444.43g/mol

Tetracycline-13C2-d6 (Oxytetracycline EP Impurity B-13C2-d6)

CAS: 60-54-8

• Formula: C₂₀₁₃C₂H₁₈D₆N₂O₈
• Peso molecolare: 452.46

Tetracycline 13C22,15N2 dried down 2.5 µg/mL

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈
• Colore e forma: Single Solution
• Peso molecolare: 468.26

Tetracycline dried down 2.5 µg/mL

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈
• Colore e forma: Single Solution
• Peso molecolare: 444.43

Tetracycline (Oxytetracycline EP Impurity B)

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈
• Peso molecolare: 444.45

Tetracycline base

CAS: 60-54-8

• Formula: C₂₂H₂₄N₂O₈·xH₂O
• Purezza: ≥ 91.0%
• Colore e forma: Light-yellow to dark yellow powder
• Peso molecolare: 444.43 (anhydrous)

Tetracycline

CAS: 60-54-8

Impurity Oxytetracycline Hydrochloride EP Impurity B Applications Tetracycline is a compound that has been shown …

• Formula: C₂₂H₂₄N₂O₈
• Colore e forma: Yellow
• Peso molecolare: 444.43

Tetracycline-d6 (80%)

CAS: 60-54-8

Stability Light Sensitive Applications Antibiotic substance produced by Streptomyces spp. Antiamebic; antibacterial; antirickettsial. References Weiss, …

• Formula: C₂₂D₆H₁₈N₂O₈
• Purezza: 80%
• Colore e forma: Light Yellow To Brown
• Peso molecolare: 450.47

Tetracycline - Bio-X ™

CAS: 60-54-8

Tetracycline is a broad-spectrum antibiotic that is effective against a variety of bacterial infections. It …

• Formula: C₂₂H₂₄N₂O₈
• Purezza: Min. 95%
• Colore e forma: Powder
• Peso molecolare: 444.43 g/mol

Tetracycline

CAS: 60-54-8

Antibiotic of tetracycline class; protein synthesis inhibitor

• Formula: C₂₂H₂₄N₂O₈
• Purezza: Min. 91 Area-%
• Colore e forma: Powder
• Peso molecolare: 444.43 g/mol

Tetracycline-d6

CAS: 60-54-8

Antibiotic of tetracycline class; protein synthesis inhibitor

• Purezza: Min. 95%