CAS 60-54-8

(-)-Tetraciclina

Descrizione:

(-)-Tetraciclina è un antibiotico ad ampio spettro appartenente alla classe delle tetracicline, caratterizzato dalla sua capacità di inibire la sintesi proteica batterica. È derivato dal batterio Streptomyces aureofaciens ed è noto per la sua efficacia contro un'ampia gamma di batteri gram-positivi e gram-negativi. La struttura chimica di (-)-Tetraciclina presenta un sistema a quattro anelli con più gruppi funzionali, inclusi gruppi idrossilici e dimetilamminici, che contribuiscono alla sua solubilità e attività biologica. Questo composto mostra proprietà come una buona biodisponibilità orale e una vita media relativamente lunga, consentendo regimi di trattamento efficaci. (-)-Tetraciclina è anche noto per i suoi potenziali effetti collaterali, tra cui disturbi gastrointestinali e fotosensibilità. Inoltre, è stato utilizzato in varie applicazioni oltre alla medicina umana, inclusa la medicina veterinaria e l'agricoltura, in particolare nel trattamento delle infezioni e come promotore della crescita nel bestiame. Il suo meccanismo d'azione coinvolge principalmente il legame alla subunità ribosomiale 30S, impedendo così l'attacco dell'aminoacil-tRNA e inibendo la sintesi proteica nei batteri.

Formula: C₂₂H₂₄N₂O₈

InChI: InChI=1S/C22H24N2O8/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30)/t9-,10-,15-,21+,22-/m0/s1

InChI key: InChIKey=OFVLGDICTFRJMM-WESIUVDSSA-N

SMILES: O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H]

Sinonimi:

• (4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• (4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide hydrochloride (1:1)
• (4S,4aS,6S,12aS)-4-(dimethylamino)-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, [4S-(4α,4aα,5aα,6β,12aα)]-
• 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide
• 6-Methyl-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxo-2-naphthacenecarboxamide
• Abramycin
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• Achromycin (naphthacene derivative)
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• Ambramicina
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• Bio-Tetra
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• Calociclina
• Ciclibion
• Cyclomycin
• Cytome
• Deschlorobiomycin
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• Economycin
• Enterocycline
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• Ibicyn
• Kinciclina
• Latycin
• Limecycline
• Medocycline
• Mericycline
• Micycline
• Neocycline
• NorTet
• Novo-Tetra
• Nsc 108579
• Nu-Tetra
• Omegamycin
• Orlycycline
• Panmycin
• Polycycline
• Polycycline (antibiotic)
• Quimocyclin N
• Quimpe Antibiotico
• Resteclin
• Retet
• Robitet Robicaps
• Roviciclina
• Sagittacin N
• Servitet
• Spaciclina
• Steclin V
• Sumycin syrup
• Tetra Hubber
• Tetra-Co
• Tetra-Proter
• Tetrabioptal
• Tetracap
• Tetraciclina
• Tetracitro S
• Tetracyclin
• Tetracycline Base
• Tetracycline Free Base
• Tetradecin
• Tetrafil
• Tetrafosammina
• Tetralan
• Tetralen
• Tetramig
• Tetramykoin
• Tetraseptine
• Triphacycline
• Veracin

Tetracycline Hydrochloride

CAS: 60-54-8, 64-75-5

Formula: C₂₂H₂₄N₂O₈·HCl

Purezza: >98.0%(T)

Colore e forma: Light yellow to Amber to Dark green powder to crystal

Peso molecolare: 480.90

Ref: 3B-T2525

Tetracycline

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈

Purezza: >95.0%(T)(HPLC)

Colore e forma: Light yellow to Yellow powder to crystal

Peso molecolare: 444.44

Ref: 3B-T3971

Tetracycline

CAS: 60-54-8

Tetracycline, 60-54-8, is a broad-spectrum napthacene antibiotic which inhibits bacterial protein synthesis by binding the 30S ribosomal subunit. Learn more.

Formula: C₂₂H₂₄N₂O₈

Colore e forma: Yellow to orange to brown, Crystalline powder or powder

Peso molecolare: 444.44

Ref: 02-J61714

Tetracycline

CAS: 60-54-8

Tetracycline (Tetracyclin) is a broad-spectrum antibiotic. Tetracycline is commonly used in anti-infective studies. Cost-effective and quality-assured.

Formula: C₂₂H₂₄N₂O₈

Purezza: 92.65% - 98.18%

Colore e forma: Light Yellow Crystal

Peso molecolare: 444.43

Ref: TM-T0912L

(4S,4aS,5aS,6S,12aS)-4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthacenecarboxamide

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 444.4346

Ref: IN-DA003UNG

Tetracycline, EP grade

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈

Purezza: 88.0 - 102.0 % (dried basis)

Colore e forma: Yellow crystalline powder

Peso molecolare: 444.43

Ref: 7W-GA0548

Tetracycline

CAS: 60-54-8

Tetracycline

Purezza: ≥80%

Peso molecolare: 444.43g/mol

Ref: 54-BUP17381

Tetracycline-13C2-d6 (Oxytetracycline EP Impurity B-13C2-d6)

CAS: 60-54-8

Formula: C₂₀₁₃C₂H₁₈D₆N₂O₈

Peso molecolare: 452.46

Ref: 4Z-T-4027

Tetracycline base

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈·xH₂O

Purezza: ≥ 91.0%

Colore e forma: Light-yellow to dark yellow powder

Peso molecolare: 444.43 (anhydrous)

Ref: 7W-GA9779

Tetracycline 13C22,15N2 dried down 2.5 µg/mL

Prodotto controllato

CAS: 60-54-8

Formula: C₂₂H₂₄₁₅N₂O₈

Colore e forma: Single Solution

Peso molecolare: 468.26

Ref: 04-S17396147DD-2.5

Tetracycline dried down 2.5 µg/mL

Prodotto controllato

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈

Colore e forma: Single Solution

Peso molecolare: 444.43

Ref: 04-A17396145DD-2.5

Tetracycline (Oxytetracycline EP Impurity B)

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈

Peso molecolare: 444.45

Ref: 4Z-T-4030

Tetracycline

CAS: 60-54-8

Impurity Oxytetracycline Hydrochloride EP Impurity B
Applications Tetracycline is a compound that has been shown to induce apoptosis in various cells. Tetracycline was a useful compound to study drug resistance of pathogens of infections in patients with severe liver disease.
References Yao, L., et al.: Zhongguo Linchuang Yanjiu, 29, 1510 (2016)

Formula: C₂₂H₂₄N₂O₈

Colore e forma: Yellow

Peso molecolare: 444.43

Ref: TR-T291413

Tetracycline - Bio-X ™

CAS: 60-54-8

Tetracycline is a broad-spectrum antibiotic that is effective against a variety of bacterial infections. It is a polyketide antibiotic that inhibits protein synthesis by binding to ribosomes and preventing the attachment of amino acids to tRNA molecules thus inhibiting bacterial growth.

Formula: C₂₂H₂₄N₂O₈

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 444.43 g/mol

Ref: 3D-BT166207

Tetracycline

CAS: 60-54-8

Antibiotic of tetracycline class; protein synthesis inhibitor

Formula: C₂₂H₂₄N₂O₈

Purezza: Min. 91 Area-%

Colore e forma: Powder

Peso molecolare: 444.43 g/mol

Ref: 3D-AT35208

(4S,4aS,5aS,6S,12aS)-4-(dimethylamino)-6,10,12,12a-tetrahydroxy-6-methyl-1,3,11-trioxo-1,2,3,4,4a,5,5a,6,11,12a-decahydrotetracene-2-carboxamide

CAS: 60-54-8

Purezza: 96%

Peso molecolare: 444.4400024

Ref: 10-F862906

Lymecycline EP Impurity H

CAS: 60-54-8

Formula: C₂₂H₂₄N₂O₈

Peso molecolare: 444.44

Ref: ST-EA-CP-L64008

Tetracycline-d6

CAS: 60-54-8

Tetracycline-d6 is an antibiotic that inhibits the growth of bacteria by binding to the ribosomal subunit. Tetracycline-d6 is used in the treatment of urinary infections caused by E. coli, Enterobacter cloacae, Klebsiella pneumoniae, and Proteus mirabilis. Tetracycline-d6 has been shown to have antimicrobial activity against a wide range of microorganisms including gram negative and gram positive bacteria, as well as fungi and protozoa. It has been shown to be active against methicillin resistant strains such as S. aureus (MRSA), with an antibacterial efficacy comparable to that of erythromycin. The tetracycline resistance gene is located on plasmids and can be transferred between bacterial cells through conjugation or transduction. Tetracycline-d6 is often used in combination with beta lactam antibiotics such as pen

Purezza: Min. 95%

Ref: 3D-FT180092