CAS 60-81-1

Floridzina

Descrizione:

Floridzina, con il numero CAS 60-81-1, è un glicoside flavonoide che si trova naturalmente principalmente nella corteccia dei meli e di altre piante. È caratterizzato dalla sua struttura chimica, che consiste in uno scheletro di florentina legato a una molecola di glucosio. Floridzina presenta diverse proprietà biologiche notevoli, tra cui effetti antiossidanti, anti-infiammatori e potenziali effetti anti-diabetici, poiché può inibire il riassorbimento del glucosio nei reni. Questo composto è anche noto per il suo ruolo nei meccanismi di difesa delle piante ed è stato studiato per i suoi potenziali benefici per la salute negli esseri umani, in particolare in relazione ai disturbi metabolici. In termini di proprietà fisiche, Floridzina è tipicamente una polvere cristallina bianca a gialla pallida, solubile in acqua e solventi organici. La sua stabilità può essere influenzata da fattori come pH e temperatura. A causa delle sue diverse attività biologiche, Floridzina ha suscitato interesse sia nella ricerca farmacologica che nell'industria alimentare, in particolare nel contesto di alimenti funzionali e integratori alimentari.

Formula: C₂₁H₂₄O₁₀

InChI: InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1

InChI key: InChIKey=IOUVKUPGCMBWBT-QNDFHXLGSA-N

SMILES: C(CCC1=CC=C(O)C=C1)(=O)C2=C(O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C=C(O)C=C2O

Sinonimi:

• 1-Propanone, 1-[2-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-
• 1-[2-(β-<span class="text-smallcaps">D</span>-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
• 1-[2-(β-D-Glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-1-propanone
• 2'-(β-D-Glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenon
• 2'-(β-D-glucopiranosiloxi)-4',6'-dihidroxi-3-(4-hidroxifenil)propiofenona
• 2'-(β-D-glucopyrannosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone
• 2'-(β-D-glucopyranosyloxy)-4',6'-dihydroxy-3-(4-hydroxyphenyl)propiophenone
• Dihydrochalcone 2′-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Floridzin
• Nsc 2833
• Phloretin 2'-O-glucoside
• Phloretin 2'-glucoside
• Phloretin 2′-O-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Phloretin 2′-β-<span class="text-smallcaps">D</span>-Glucoside
• Phloretin glucoside
• Phlorhizin
• Phloridzin
• Phloridzosid
• Phlorizin
• Phlorizine
• Phlorizoside
• Phlorrhizin
• 1-Propanone, 1-[2-(β-D-glucopyranosyloxy)-4,6-dihydroxyphenyl]-3-(4-hydroxyphenyl)-
• 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl β-D-glucopyranoside
• 3,5-dihydroxy-2-[3-(4-hydroxyphenyl)propanoyl]phenyl hexopyranoside
• Phlorizin dihydrate

Phlorizin

CAS: 60-81-1, 7061-54-3

Formula: C₂₁H₂₄O₁₀

Purezza: >97.0%(T)(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 436.41

Ref: 3B-P0248

Phloridzin

CAS: 60-81-1

Phloridzin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₄O₁₀

Purezza: (HPLC) ≥99%

Colore e forma: Powder

Peso molecolare: 436.42

Ref: 11-1361S

Phlorizin

CAS: 60-81-1

Phlorizin

Purezza: 98%

Peso molecolare: 436.41g/mol

Ref: 54-OR1029277

Phlorizin

CAS: 60-81-1

Phlorizin

Purezza: ≥98%

Peso molecolare: 436.41g/mol

Ref: 54-BUP18505

Phlorizin

CAS: 60-81-1

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 436.4129943847656

Ref: 10-F079095

Phloridzin

CAS: 60-81-1

Formula: C₂₁H₂₄O₁₀

Purezza: 95%~99%

Peso molecolare: 436.413

Ref: BP-BP1089

Phlorizin

CAS: 60-81-1

Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .

Formula: C₂₁H₂₄O₁₀

Purezza: 99.73% - 99.77%

Colore e forma: Solid Crystalline

Peso molecolare: 436.41

Ref: TM-T2922

Phloridzin

CAS: 60-81-1

Formula: C₂₁H₂₄O₁₀

Purezza: ≥ 98.0%

Colore e forma: Off-white to light yellow powder

Peso molecolare: 436.41

Ref: 7W-GC6883

Phloridzin

CAS: 60-81-1

Natural glycoside

Formula: C₂₁H₂₄O₁₀

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 436.42

Ref: 5G-80513

Phloridzin

Prodotto controllato

CAS: 60-81-1

Applications It is a dihydrochalcone occurring in all parts of the apple tree except the mature fruit. Once thought to occur in pear, plum, cherry trees and other Rosaceae. Inhibitor of Na+-glucose cotransporters (SGLT). inhibits both SGLT1 and SGLT2 with low therapeutic selectivity. Cytotoxic to Breast Cancer cells with potent antioxidant and antibacterial activity. Produces renal glycosuria and blocks intestinal glucose absorption. Normalizes insulin sensitivity in diabetic rats.
References Moelwyn-Hughes EA, 1930. J Gen Physiol. Jul 20;13(6):807-17.Chang-Ik, 2016. Molecules, 21, 1136Fernando W, et al. 2016. Carcinogenesis. 2016 Oct;37(10):1004-13

Formula: C₂₁H₂₄O₁₀

Colore e forma: Neat

Peso molecolare: 436.41

Ref: TR-P339500

Phloridzin

CAS: 60-81-1

Phloridzin is a flavonoid glycoside, which is primarily sourced from apple trees and other members of the Rosaceae family. It is naturally found in the bark, roots, and other parts of the plant. The mode of action of phloridzin involves its function as an inhibitor of the sodium-glucose transporters (SGLT1 and SGLT2). By blocking these transporters, phloridzin prevents the reabsorption of glucose in the renal tubules, thus promoting the excretion of glucose through urine.

Formula: C₂₁H₂₄O₁₀

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 436.41 g/mol

Ref: 3D-MP08132