CAS 60325-46-4

Sulprostone

Descrizione:

Sulprostone è un analogo sintetico della prostaglandina E1, utilizzato principalmente per le sue proprietà farmacologiche in ostetricia e ginecologia. È caratterizzato dalla sua capacità di indurre contrazioni uterine ed è spesso utilizzato in procedure mediche come l'induzione del parto e la gestione di alcuni tipi di aborto. La sostanza agisce legandosi a recettori specifici delle prostaglandine, portando a un aumento dell'attività del muscolo liscio nell'utero. Sulprostone viene tipicamente somministrato per iniezione e ha una emivita relativamente breve, richiedendo un attento dosaggio e monitoraggio. La sua struttura chimica include un gruppo idrossile e un acido carbossilico, contribuendo alla sua attività biologica. Sebbene sia efficace, l'uso di Sulprostone può essere associato a effetti collaterali come disturbi gastrointestinali ed effetti cardiovascolari, che richiedono considerazione durante il trattamento. Come per qualsiasi farmaco, il suo uso dovrebbe essere guidato da protocolli clinici e fattori specifici del paziente per garantire sicurezza ed efficacia.

Formula: C₂₃H₃₁NO₇S

InChI: InChI=1/C23H31NO7S/c1-32(29,30)24-23(28)12-8-3-2-7-11-19-20(22(27)15-21(19)26)14-13-17(25)16-31-18-9-5-4-6-10-18/h2,4-7,9-10,13-14,17,19-20,22,25,27H,3,8,11-12,15-16H2,1H3,(H,24,28)/t17-,19-,20-,22-/m1/s1

InChI key: InChIKey=UQZVCDCIMBLVNR-TWYODKAFSA-N

SMILES: C(=C/[C@H](COC1=CC=CC=C1)O)\[C@@H]2[C@@H](C/C=C\CCCC(NS(C)(=O)=O)=O)C(=O)C[C@H]2O

Sinonimi:

• (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
• (5Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl}-N-(methylsulfonyl)hept-5-enamide
• (5Z)-7-{(1R,2R,3R)-3-hydroxy-2-[(1E)-3-hydroxy-4-phenoxybut-1-en-1-yl]-5-oxocyclopentyl}-N-(methylsulfonyl)hept-5-enamide
• 5-Heptenamide, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-butenyl]-5-oxocyclopentyl]-N-(methylsulfonyl)-, (5Z)-
• 5-Heptenamide, 7-[3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl]-N-(methylsulfonyl)-, [1R-[1α(Z),2β(1E,3R*),3α]]-
• 5-heptenamide, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3R)-3-hydroxy-4-phenoxy-1-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-, (5Z)-
• 60325-46-4
• 7-[(1R,2R,3R)-3-hydroxy-2-[(3R)-3-hydroxy-4-phenoxy-but-1-enyl]-5-oxo-cyclopentyl]-N-methylsulfonyl-hept-5-enamide
• Cp 34089
• Nalador
• Shb 286
• Zk 57671
• [1R-[1a(Z),2b(1E,3R*),3a]]-7-[3-Hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
• Sulprostone
• (5z,11α,13e,15r)-11,15-dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide
• 5-heptenamide,7-(3-hydroxy-2-(3-hydroxy-4-phenoxy-1-butenyl)-5-oxocyclopentyl)
• Sulprostone USP/EP/BP
• N-(METHYLSULFONYL)-9-OXO-11ALPHA,15R-DIHYDROXY-16-PHENOXY-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-AMIDE
• (5Z,11alpha,13E,15R)-11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranor-prosta-5Z,13E-dien-1-amide
• (5Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3R)-3-hydroxy-4-buten-1-yl]-5-oxocyclopentyl]-N-(methylsulfonyl)-5-heptenamide
• CP-34089, SHB-286, ZK-57671, (5Z,11α,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide
• 16-phenoxy-omega-17,18,19,20-tetranorpge-2methylsulfonylamide
• sch286
• 16-phenoxy-omega-17,18,19,20-tetranorprostaglandine2methylsulfonylamide
• (1r-(1-alpha(z),2-beta(1e,3r*),3-alpha))--n-(methylsulfonyl)
• (5Z,11ALPHA,13E,15R)-11,15-DIHYDROXY-9-OXO-16-PHENOXY-17,18,19,20-TETRANORPROSTA-5,13-DIENOIC ACID METHANE SULFONAMIDE
• 16-phenoxy-17,18,19,20tetranorprostaglandine(sub2)methylsulfonylamide
• CP-34086
• (Z)-7-[(1R,2R,3R)-3-Hydroxy-2-[(E,3R)-3-hydroxy-4-(phenoxy)but-1-enyl]-5-oxocyclopentyl]-N-methylsulfonylhept-5-enamide
• (5Z,11a,13E,15R)--11,15-Dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-5,13-dienoic acid methane sulfonamide

Sulprostone

CAS: 60325-46-4

Formula: C₂₃H₃₁NO₇S

Peso molecolare: 465.56

Ref: 7W-GL7918

Sulprostone

CAS: 60325-46-4

EP3 and EP1 receptor agonist

Formula: C₂₃H₃₁NO₇S

Purezza: 98%

Colore e forma: White To Off-White Solid

Peso molecolare: 465.56

Ref: TM-T23404