CAS 61-76-7

Cloridrato di (-)-fenilefrina

Descrizione:

Cloridrato di (-)-fenilefrina è un'amina simpaticomimetica sintetica utilizzata principalmente come decongestionante e vasopressore. È caratterizzata dalla sua capacità di stimolare selettivamente i recettori adrenergici alfa-1, portando a vasocostrizione e aumento della pressione sanguigna. Questo composto è tipicamente presentato come una polvere cristallina bianca o bianco sporco, solubile in acqua e alcol, il che facilita il suo utilizzo in varie formulazioni farmaceutiche. La formula molecolare di Cloridrato di (-)-fenilefrina è C9H13NO2·HCl, e ha un peso molecolare che riflette i suoi componenti strutturali, inclusi un gruppo fenolico e una catena laterale di etilamina. La sua stereochimica è significativa, poiché l'enantiomero (-) è la forma attiva responsabile dei suoi effetti terapeutici. Comunemente trovato in farmaci da banco, è utilizzato per alleviare la congestione nasale e come agente midriatico in oftalmologia. Tuttavia, è essenziale monitorare il suo utilizzo a causa dei potenziali effetti collaterali, inclusi ipertensione e bradicardia riflessa, particolarmente in popolazioni sensibili.

Formula: C₉H₁₃NO₂·ClH

InChI: InChI=1S/C9H13NO2.ClH/c1-10-6-9(12)7-3-2-4-8(11)5-7;/h2-5,9-12H,6H2,1H3;1H/t9-;/m0./s1

InChI key: InChIKey=OCYSGIYOVXAGKQ-FVGYRXGTSA-N

SMILES: [C@@H](CNC)(O)C1=CC(O)=CC=C1.Cl

Sinonimi:

• (-)-α-Hydroxy-β-(methylamino)ethyl-α-(3-hydroxybenzene)hydrochloride
• (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• (R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride
• (R)-3-Hydroxy-[α-(methylamino)methyl]benzene methanol hydrochloride
• (R)-3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• (R)-Phenylephrine hydrochloride
• 3-Hydroxy-alpha-(methylaminomethyl)benzyl alcohol hydrochloride
• Adrianol
• Ak-Dilate
• Ak-Nefrin
• Alcon Efrin
• Almefrin
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride (1:1), (αR)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (R)-
• Benzenemethanol, 3-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (αR)-
• Benzyl alcohol, m-hydroxy-α-[(methylamino)methyl]-, hydrochloride, (-)-
• D-(-)-Phenylephrinehydrochloride
• Decadron
• Fenilefrina, Clorhidrato
• Irifrin
• Isophrin
• Isophrin hydrochloride
• Levophenylephrine hydrochloride
• Lexatol
• M-Sympatol
• Meta-Sympatol
• Meta-Synephrine hydrochloride
• Metaoxedrine chloride
• Metaoxedrine hydrochloride
• Mydfrin
• Neo-Synephrine hydrochloride
• Neo-Synesin 1
• Neophryn
• Neosinesine
• Nostril
• Oftalfrine
• Phenylephrine HCL
• Phenylephrine Hydrochloride
• Phenylephrine, chlorhydrate
• Phenylephrinhydrochlorid
• Prefrin
• Pyracort D
• R-(-)-m-Synephrine hydrochloride
• Sucraphen
• Synasal
• l-1-(m-Hydroxyphenyl)-2-methylaminoethanol hydrochloride
• l-m-Hydroxy-α-[(methylamino)methyl]benzyl alcohol hydrochloride
• l-α-Hydroxy-β-methylamino-3-hydroxy-1-ethylbenzene hydrochloride

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystaline

Peso molecolare: 203.67

Ref: 3B-P0398

Phenylephrine Hydrochloride

CAS: 61-76-7

Colore e forma: Neat

Ref: 61-FOR0081.00

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride

Formula: C₉H₁₃NO₂HCl

Purezza: 100.0%

Colore e forma: White

Peso molecolare: 203.07131

Ref: 47-284

PHENYLEPHRINE HYDROCHLORIDE CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE CRS

Ref: 41-P1250000

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

CAS: 61-76-7

PHENYLEPHRINE HYDROCHLORIDE FOR PEAK IDENTIFICATION CRS

Formula: C₉H₁₄ClNO₂

Peso molecolare: 203.666

Ref: 41-Y0000683

Phenylephrine Hydrochloride

CAS: 61-76-7

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₉H₁₃NO₂·ClH

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 203.07131

Ref: 45-1533002

Phenylephrine hydrochloride

CAS: 61-76-7

Phenylephrine hydrochloride (NCI-c55641) is a selective agonist of the α1-adrenergic receptor.

Formula: C₉H₁₄ClNO₂

Purezza: 99.51% - 99.97%

Colore e forma: Physical Description Odorless White Microcrystalline Powder Bitter Taste Ph (1%

Peso molecolare: 203.67

Ref: TM-T0453

(R)-3-(1-Hydroxy-2-(methylamino)ethyl)phenol hydrochloride

CAS: 61-76-7

Formula: C₉H₁₄ClNO₂

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 203.6660

Ref: IN-DA00IAS9

Phenylephrine HCl

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Colore e forma: White To Off-White Solid

Peso molecolare: 167.21 36.46

Ref: 4Z-P-2624

(R)-(-)-Phenylephrine hydrochloride, USP grade

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Purezza: 97.5 - 102.0 %

Colore e forma: White to off-white powder

Peso molecolare: 203.67

Ref: 7W-GL0912

(R)-(-)-Phenylephrine hydrochloride

CAS: 61-76-7

Formula: C₉H₁₃NO₂·HCl

Purezza: (Titration) ≥ 99.0% (dried basis)

Colore e forma: White to off-white powder

Peso molecolare: 203.67

Ref: 7W-GL9617

Phenylephrine Hydrochloride

CAS: 61-76-7

Colore e forma: Neat

Ref: 86-MM0081.00

Phenylephrine Hydrochloride

CAS: 61-76-7

Formula: C₉H₁₃NO₂HCl

Peso molecolare: 167.21 : 36.46

Ref: ST-EA-CP-P12016

(R)-Phenylephrine Hydrochloride

CAS: 61-76-7

Stability Hygroscopic
Applications (R)-Phenylephrine Hydrochloride is an α-Adrenergic agonist. Mydriatic; decongestant.
References Warren, M.R., et al.: J. Pharmacol. Exp. Ther., 86, 284 (1946); Gaglia, C.A., et al.: Anal. Profiles Drug Subs., 3, 483 (1974);

Formula: C₉H₁₃NO₂·ClH

Colore e forma: White To Off-White

Peso molecolare: 203.67

Ref: TR-P320640

Phenylephrine hydrochloride

CAS: 61-76-7

(R)-Phenylephrine hydrochloride is a non selective alpha adrenergic agonist that can be used as a bronchodilator or vasopressor. Some research studies in rat liver microsomes has shown that (R)-phenylephrine can be converted to phenylephrine by alcohol dehydrogenase at a rate constant of around 1.8x103 M-1s-1 at 37°C. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle and increase blood pressure by stimulating alpha-adrenergic receptors in the body. This drug is also used in chromatography for control analysis and detection of adulteration with other compounds, such as norepinephrine, with the help of benzalkonium chloride.In ophthalmology, phenylephrine hydrochloride formulations are used for the treatment of eye disorders such as myopia, hypermetropia and astigmatism. It increases the outflow of aqueous humour from the eye by acting on alpha receptors in the ciliary body, and seems to be effective in controlling symptoms of allergic rhinitis and chronic urticaria.

Formula: C₉H₁₄NO₂Cl

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 203.67 g/mol

Ref: 3D-FP26956

(R)-Phenylephrine HCl - Bio-X ™

CAS: 61-76-7

(R)-Phenylephrine is a non-selective α1-adrenoceptor agonist that can be used as a bronchodilator or vasopressor. The biological effects of this compound are due to its ability to cause relaxation of smooth muscle cells and increase blood pressure by stimulating alpha-adrenergic receptors in the body. Also, this drug is used to relieve nasal discomfort caused by colds and allergies and is used to relieve sinus congestion and pressure.

Formula: C₉H₁₃NO₂•HCl

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 203.67 g/mol

Ref: 3D-BP166231