CAS 6119-47-7

Cloridrato di chinina diidrato

Descrizione:

Cloridrato di chinina diidrato è un composto chimico derivato dalla corteccia dell'albero della china, noto principalmente per il suo uso come agente antimalarico. È una polvere cristallina bianca o bianco sporco che è solubile in acqua, il che facilita il suo utilizzo in varie formulazioni farmaceutiche. Il composto ha un sapore amaro, caratteristico della chinina, ed è spesso utilizzato nell'acqua tonica e in altre bevande per aromatizzare. Cloridrato di chinina diidrato ha una formula molecolare che include sia chinina che acido cloridrico, insieme a due molecole d'acqua, contribuendo alla sua classificazione come diidrato. Oltre alle sue proprietà antimalariche, è stato studiato per i suoi potenziali effetti analgesici e anti-infiammatori. Il composto agisce interferendo con la capacità del parassita di metabolizzare e utilizzare l'emoglobina, portando infine alla sua morte. Le considerazioni sulla sicurezza e sul dosaggio sono cruciali, poiché un'assunzione eccessiva può portare a effetti collaterali come cinchonismo, caratterizzato da sintomi come acufene e nausea. In generale, Cloridrato di chinina diidrato rimane un composto importante sia in contesti medicinali che culinari.

Formula: C₂₀H₂₄N₂O₂·ClH·2H₂O

InChI: InChI=1S/C20H24N2O2.ClH.2H2O/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18;;;/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3;1H;2*1H2/t13-,14-,19-,20+;;;/m0.../s1

InChI key: InChIKey=MPQKYZPYCSTMEI-FLZPLBAKSA-N

SMILES: [C@@H](O)(C=1C2=C(C=CC(OC)=C2)N=CC1)[C@]3([N@@]4C[C@H](C=C)[C@](C3)(CC4)[H])[H].Cl.O

Sinonimi:

• (4beta,8alpha,9R)-6'-methoxycinchonan-9-ol hydrochloride dihydrate
• (9R)-6'-methoxycinchonan-1'-ium-9-ol chloride dihydrate
• (R)(6-Methoxy-4-quinolyl)(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol hydrochloride
• Cinchonan-9-ol, 6′-methoxy-, hydrochloride, hydrate (1:1:2), (8α,9R)-
• Cinchonan-9-ol, 6′-methoxy-, monohydrochloride, dihydrate, (8α,9R)-
• Quinine Hydrochloride Dihydrate

Quinine Hydrochloride Dihydrate

CAS: 6119-47-7

Formula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 396.91

Ref: 3B-Q0030

Quinine monohydrochloride dihydrate, 99% (total base), may contain up to 10% Dihydroquinine

CAS: 6119-47-7

It is used as pharmaceutical intermediate. Benzoylthiophenes are allosteric enhancers (AE) of agonist activity at the A1 adenosine receptor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to t

Formula: C₂₀H₂₉ClN₂O₄

Purezza: 99%

Colore e forma: Powder or crystalline powder or needles, White to pale cream

Peso molecolare: 396.91

Ref: 02-H33474

Quinine.HCl.dihydrate, 1mg/ml in Ethanol (as free base)

CAS: 6119-47-7

Colore e forma: Single Solution

Ref: LP-QUN-1135-HC-1LE

Quinine.HCl.dihydrate

CAS: 6119-47-7

Colore e forma: Neat

Ref: LP-QUN-1135-HC-10

Quinine Hydrochloride Dihydrate

CAS: 6119-47-7

Quinine and its salts

Formula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Colore e forma: Colorless Needles

Peso molecolare: 396.18159

Ref: 45-1596807

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Formula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Purezza: 99.0 - 101.0 %

Colore e forma: White or almost white crystalline powder

Peso molecolare: 396.91

Ref: 7W-GA8217

Quinine monohydrochloride dihydrate

CAS: 6119-47-7

Quinine monohydrochloride dihydrate

Formula: C₂₀H₂₄N₂O₂·ClH·2H₂O

Purezza: By hplc: 99.6% by area (Typical Value in Batch COA)

Colore e forma: white crystalline powder

Peso molecolare: 396.91g/mol

Ref: 54-BIQ1204

Quinine hydrochloride dihydrate, 10mM (in DMSO)

CAS: 6119-47-7

Quinine hydrochloride dihydrate, 10mM (in DMSO)

Purezza: ≥98%

Peso molecolare: 396.91g/mol

Ref: 54-BUP19126

Quinine Hydrochloride Dihydrate

Prodotto controllato

CAS: 6119-47-7

Formula: C₂₀H₂₄N₂O₂·ClHH₂O

Colore e forma: Neat

Peso molecolare: 396.91

Ref: 86-MM1736.00

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Quinine hydrochloride dihydrate (Quinine HCl Dihydrate) is a white crystalline K+ channel blocker, used to treat malaria.

Formula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Purezza: 99.91%

Colore e forma: White To Light Yellow Crystal Powder

Peso molecolare: 396.91

Ref: TM-T6631

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Formula: C₂₀H₂₉ClN₂O₄

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 396.91

Ref: 10-F222360

Quinidine Hydrochloride Dihydrate

Prodotto controllato

CAS: 6119-47-7

Applications Quinidine Hydrochloride Dihydrate is a salt of Quinidine (Q685000), a dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial.
References Loutfy, M.A., et al.: Anal. Profiles Drug Subs., 12, 483 (1983), Mason, J. W., et al.: Ann. N. Y. Acad. Sci., 432, 162 (1984),

Formula: C₂₀H₂₄N₂O₂·ClH·2H₂O

Colore e forma: White

Peso molecolare: 396.91

Ref: TR-Q685045

Quinine hydrochloride dihydrate

CAS: 6119-47-7

Quinine hydrochloride dihydrate is a natural compound that has been used for centuries as a treatment for malaria. It is an effective anti-malarial agent and is also used to treat nocturnal leg cramps, although it has a low potency. Quinine hydrochloride dihydrate is active against the parasite Plasmodium falciparum in vitro. It binds to hemozoin, which is the pigment that the malaria parasites produce during digestion of hemoglobin from red blood cells. This binding inhibits the growth of the parasite and causes cell death by inhibiting protein synthesis. Quinine hydrochloride dihydrate has been shown to be genotoxic in vivo, but not in vitro. The genotoxic effects may be due to its ability to create reactive oxygen species (ROS) through photochemical reactions with light exposure and other chemical reactions, such as thermal expansion or matrix effects.

Formula: C₂₀H₂₄N₂O₂·HCl·2H₂O

Colore e forma: Powder

Peso molecolare: 396.91 g/mol

Ref: 3D-FQ43018