CAS 61318-91-0

nitrato di sulconazolo

Descrizione:

nitrato di sulconazolo è un agente antifungino utilizzato principalmente nel trattamento delle infezioni dermatologiche, in particolare quelle causate da funghi e lieviti. Appartiene alla classe dei derivati imidazolici, noti per la loro capacità di inibire la sintesi dell'ergosterolo, un componente critico delle membrane cellulari fungine. Questo meccanismo interrompe l'integrità della cellula fungina, portando alla morte cellulare. nitrato di sulconazolo è tipicamente formulato come una crema o soluzione topica, consentendo un trattamento localizzato con un'assorbimento sistemica minima. Il composto è caratterizzato dalla sua relativamente bassa solubilità in acqua, che ne migliora l'efficacia nelle applicazioni topiche. Inoltre, presenta un ampio spettro di attività antifungina contro vari patogeni, rendendolo un'opzione preziosa in contesti clinici. I profili di sicurezza indicano che è generalmente ben tollerato, con effetti collaterali rari e tipicamente lievi. Come per qualsiasi farmaco, è essenziale utilizzare nitrato di sulconazolo come indicato da un professionista sanitario per garantire risultati terapeutici ottimali e ridurre al minimo il rischio di sviluppo di resistenza.

Formula: C₁₈H₁₆Cl₃N₃O₃S

InChI: InChI=1/C18H15Cl3N2S.HNO3/c19-14-3-1-13(2-4-14)11-24-18(10-23-8-7-22-12-23)16-6-5-15(20)9-17(16)21;2-1(3)4/h1-9,12,18H,10-11H2;(H,2,3,4)

InChI key: InChIKey=CRKGMGQUHDNAPB-UHFFFAOYSA-N

SMILES: C(CN1C=CN=C1)(SCC2=CC=C(Cl)C=C2)C3=C(Cl)C=C(Cl)C=C3.N(=O)(=O)O

Sinonimi:

• 1-[2-(4-Chlorobenzylthio)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole nitrate
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, (±)-, mononitrate
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (1:1)
• Exelderm
• Rs 44872
• Rs 44872-00-10-3
• Sulcosyn
• Sulconazole nitrate
• Myk
• rs44872
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate (9CI)
• Sulconazole Nitrate (200 mg)
• 1-(2-(((4-chlorophenyl)methyl)thio)-2-(2,4-dichlorophenyl)ethyl)-1h-imidazol
• SULCONAZOLE NITRATE SALT
• ,mononitrate,(+-)-
• Sulconazole (mononitrate)
• Sulconazole nitrate,cas:61318-91-0
• 1H-IMidazole, 1-[2-[[(4-chlorophenyl)Methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, nitrate
• 1-[2-(P-CHLOROBENZYLTHIO)-2-(2,4-DICHLOROPHENYL)ETHYL]-1H-IMIDAZOLE NITRATE
• Sulconazole nitrate salt,1-(2-[p-Chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1H-imidazole
• Sulconazole nitrate USP/EP/BP
• 1H-Imidazole, 1-[2-[[(4-chlorophenyl)methyl]thio]-2-(2,4-dichlorophenyl)ethyl]-, mononitrate (9CI)
• (+-)-1-(2,4-dichloro-beta-((4-chlorobenzyl)thio)phenethyl)imidazolenitrate
• 1-(2-[p-chlorobenzylthio]-2-[2,4-dichlorophenyl]ethyl)-1h-imidazole
• 1-[2-[(4-chlorophenyl)methylthio]-2-(2,4-dichlorophenyl)ethyl]imidazole

Sulconazole Nitrate

CAS: 61318-91-0

Compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure nesoi

Formula: C₁₈H₁₅Cl₃N₂S

Colore e forma: White Off-White Powder

Peso molecolare: 396.00215

Ref: 45-1623681

SULCONAZOLENITRATE

CAS: 61318-91-0

Formula: C₁₈H₁₆Cl₃N₃O₃S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 460.7619

Ref: IN-DA00IAU9

Sulconazole mononitrate

CAS: 61318-91-0

Sulconazole mononitrate

Purezza: ≥98%

Peso molecolare: 460.76g/mol

Ref: 54-BUP13871

Sulconazole Nitrate

CAS: 61318-91-0

Sulconazole Nitrate

Purezza: 99%

Peso molecolare: 460.75g/mol

Ref: 54-OR1030138

Sulconazole nitrate salt

CAS: 61318-91-0

Formula: C₁₈H₁₅Cl₃N₂S·HNO₃

Purezza: ≥ 98.0%

Colore e forma: White powder

Peso molecolare: 460.76

Ref: 7W-GA8662

Sulconazole Nitrate

CAS: 61318-90-9, 61318-91-0

Formula: C₁₈H₁₅Cl₃N₂S·HNO₃

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 460.75

Ref: 3B-U0112

Sulconazole Nitrate

Prodotto controllato

CAS: 61318-91-0

Formula: C₁₈H₁₅Cl₃N₂S·HNO₃

Colore e forma: Neat

Peso molecolare: 460.76

Ref: 86-MM3674.00

Sulconazole mononitrate

CAS: 61318-91-0

"Sulconazole mononitrate (Exelderm) is a synthetic antifungal imidazole that disrupts fungal cell membranes by inhibiting ergosterol synthesis."

Formula: C₁₈H₁₅Cl₃N₂S·HNO₃

Purezza: 99.75% - 99.92%

Colore e forma: White Crystalline Powder

Peso molecolare: 460.76

Ref: TM-T6686

Sulconazole Nitrate

Prodotto controllato

CAS: 61318-91-0

Applications Sulconazole Nitrate is an antifungal agent which prevents fungal growth by inhibiting sterol synthesis.
References Kinobe, R. et al.: J. Pharmacol. Exp. Ther., 319, 277 (2006); Ooishi, T. et al.: J. Japan. Soc. Hosp. Pharm., 31, 1449 (1995);

Formula: C₁₈H₁₅Cl₃N₂S·HNO₃

Colore e forma: Neat

Peso molecolare: 460.76

Ref: TR-S688940

Sulconazole Nitrate

CAS: 61318-91-0

Sulconazole Nitrate is a broad-spectrum antimicrobial agent that inhibits the growth of fungi by interfering with the synthesis of ergosterol, an important component of fungal cell membranes. Sulconazole Nitrate has been shown to possess in vitro antifungal activity against dimorphic fungi such as Candida albicans and Cryptococcus neoformans. It also has been shown to inhibit the growth of bacteria and other microbes through inhibition of fatty acid synthesis. This drug may be used as an adjuvant therapy for autoimmune diseases or infections caused by resistant strains of bacteria. Sulconazole Nitrate binds to fatty acids in the plasma membrane and prevents their incorporation into the phospholipid bilayer. The disruption of this process results in decreased cell membrane fluidity, which leads to a loss of structural integrity and cell permeability.

Formula: C₁₈H₁₅Cl₃N₂S·HNO₃

Purezza: Min. 95%

Peso molecolare: 460.76 g/mol

Ref: 3D-FS76681