CAS 61477-96-1

Piperacillina

Descrizione:

Piperacillina è un antibiotico penicillinico semisintetico che viene utilizzato principalmente per trattare una varietà di infezioni batteriche. È efficace contro un ampio spettro di batteri gram-positivi e gram-negativi, inclusa Pseudomonas aeruginosa. Piperacillina agisce inibendo la sintesi della parete cellulare batterica, portando alla lisi cellulare e alla morte. Il composto viene tipicamente somministrato per iniezione, poiché non viene ben assorbito se assunto per via orale. La sua struttura chimica include un anello beta-lattamico, che è caratteristico delle penicilline, e una catena laterale che ne migliora l'attività contro alcuni batteri resistenti. Piperacillina è spesso combinato con un inibitore della beta-lattamasi, come il tazobactam, per estendere la sua efficacia contro organismi produttori di beta-lattamasi. Gli effetti collaterali comuni possono includere reazioni allergiche, disturbi gastrointestinali e potenziali impatti sulla funzione renale. A causa della sua attività ad ampio spettro, Piperacillina è frequentemente utilizzato in contesti ospedalieri per infezioni gravi, in particolare in pazienti immunocompromessi.

Formula: C₂₃H₂₇N₅O₇S

InChI: InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1

InChI key: InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N

SMILES: N(C([C@H](NC(=O)N1C(=O)C(=O)N(CC)CC1)C2=CC=CC=C2)=O)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]

Sinonimi:

• (2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
• 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-
• Pipracil
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsaure
• [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
• acide [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazine-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique
• acido [2S-[2α,5α,6β(S*)]]-6-[[[[(4-etil-2,3-dioxopiperazin-1-il)carbonil]amino]fenilacetil]amino]-3,3-dimetil-7-oxo-4-tia-1-azabiciclo[3.2.0]heptano-2-carboxilico
• Piperacillin

Piperacillin Sodium Salt

CAS: 59703-84-3, 61477-96-1

Formula: C₂₃H₂₆N₅NaO₇S

Purezza: >98.0%(N)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 539.54

Ref: 3B-P1774

Piperacillin, 95%

CAS: 61477-96-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₃H₂₆N₅NaO₇S

Purezza: 95%

Colore e forma: White, Powder or crystals or crystalline powder

Peso molecolare: 539.54

Ref: 02-J66143

Piperacillin

CAS: 61477-96-1

Colore e forma: Neat

Ref: 61-FOR0295.00

(2S,5R,6R)-6-[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-phenylacetamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 517.5548

Ref: IN-DA00IAVJ

Piperacillin

CAS: 61477-96-1

Purezza: ≥ 95.0%

Colore e forma: White to off-white powder

Peso molecolare: 517.56

Ref: 7W-GA9881

Piperacillin-d5 (N-ethyl-d5)

CAS: 61477-96-1

Formula: C₂₃H₂₂D₅N₅O₇S

Colore e forma: White To Off-White Solid

Peso molecolare: 522.59

Ref: 4Z-P-7410

Piperacillin

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Colore e forma: White To Off-White Solid

Peso molecolare: 517.56

Ref: 4Z-P-7421

piperacillin

CAS: 61477-96-1

piperacillin

Purezza: ≥98%

Peso molecolare: 517.55g/mol

Ref: 54-BUP16669

PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile

CAS: 10206-21-0, 104557-24-6, 113-98-4, 118443-89-3, 132-98-9, 13412-64-1, 1385046-35-4, 23325-78-2, 24356-60-3, 27164-46-1, 50370-12-2, 56238-63-2, 61336-70-7, 61477-96-1, 62893-20-3, 63358-49-6, 68373-14-8, 7081-44-9, 7177-48-2, 7240-38-2, 80370-57-6, 89786-04-9, 985-16-0

Colore e forma: Mixture

Ref: 04-A30000036WL

Piperacillin

Prodotto controllato

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Colore e forma: Neat

Peso molecolare: 517.55

Ref: 86-MM0295.00

Piperacillin

Prodotto controllato

CAS: 61477-96-1

Formula: C₂₃H₂₇N₅O₇S

Colore e forma: Neat

Peso molecolare: 517.55

Ref: 04-C16218900

piperacillin

CAS: 61477-96-1

Piperacillin (Pipercillin) is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains)

Formula: C₂₃H₂₇N₅O₇S

Purezza: 98.32% - 98.51%

Colore e forma: Solid

Peso molecolare: 517.55

Ref: TM-T8620

Piperacillin-d5 (phenyl-d5)

CAS: 61477-96-1

Formula: C₂₃H₂₂D₅N₅O₇S

Peso molecolare: 522.59

Ref: 4Z-P-749

Piperacillin

Prodotto controllato

CAS: 61477-96-1

Applications Broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial.
References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);

Formula: C₂₃H₂₇N₅O₇S

Colore e forma: White

Peso molecolare: 517.55

Ref: TR-P479950

Piperacillin-d5

Prodotto controllato

CAS: 61477-96-1

Formula: C₂₃₂H₅H₂₂N₅O₇S

Colore e forma: Off-White

Peso molecolare: 522.59

Ref: TR-P479952

Piperacillin

CAS: 61477-96-1

Piperacillin is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls by binding to penicillin-binding proteins. It is used for the treatment of serious infections caused by gram-negative organisms such as Aerogenes, Enterobacter, and Klebsiella. Piperacillin has a high MIC90 value against Staphylococcus and other gram-positive bacteria, but it is not active against β-lactamase producing strains of bacteria such as E. coli or Klebsiella pneumoniae. The MIC90 values are determined through an analytical method on different strains of bacteria and validated with a sample preparation before use in clinical trials.

Formula: C₂₃H₂₇N₅O₇S

Purezza: Min. 95 Area-%

Colore e forma: White Powder

Peso molecolare: 517.56 g/mol

Ref: 3D-FE27060

Piperacillin-d5

CAS: 61477-96-1

Piperacillin-d5 is a stable isotopically labeled antibiotic, which is synthesized chemically to incorporate deuterium atoms. It is derived from the β-lactam group of antibiotics, sharing properties with its non-labeled counterpart, piperacillin. The incorporation of five deuterium atoms allows researchers to use it as a tracer in various pharmacokinetic and metabolic studies without altering its biological activity.

Formula: C₂₃H₂₂D₅N₅O₇S

Purezza: Min. 95%

Peso molecolare: 522.59 g/mol

Ref: 3D-AP184289