CAS 6160-80-1

4-Metilumbelliferil β-D-glucuronide

Descrizione:

4-Metilumbelliferil β-D-glucuronide (MUG) è un composto sintetico comunemente usato come substrato in saggi biochimici, in particolare per la rilevazione dell'attività della β-glucuronidasi. È un solido cristallino incolore solubile in acqua e solventi organici. Il composto è caratterizzato dalle sue proprietà fluorescenti; dopo idrolisi da parte della β-glucuronidasi, rilascia 4-metilumbelliferone, che emette una forte fluorescenza blu quando eccitato dalla luce ultravioletta. Questa proprietà rende il MUG uno strumento prezioso in varie applicazioni, inclusa la microbiologia per la rilevazione di E. coli e altri batteri che producono β-glucuronidasi. Il MUG è stabile in condizioni normali di laboratorio, ma deve essere conservato in un luogo fresco e asciutto, lontano dalla luce, per mantenere la sua integrità. Devono essere adottate precauzioni di sicurezza quando si maneggia questo composto, come con qualsiasi sostanza chimica, per evitare potenziali pericoli. In generale, 4-Metilumbelliferil β-D-glucuronide è un reagente importante in saggi enzimatici e ricerche che coinvolgono processi di glucuronidazione.

Formula: C₁₆H₁₆O₉

InChI: InChI=1S/C16H16O9/c1-6-4-10(17)24-9-5-7(2-3-8(6)9)23-16-13(20)11(18)12(19)14(25-16)15(21)22/h2-5,11-14,16,18-20H,1H3,(H,21,22)/t11-,12-,13+,14-,16+/m0/s1

InChI key: InChIKey=ARQXEQLMMNGFDU-JHZZJYKESA-N

SMILES: CC=1C=2C(=CC(O[C@@H]3O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]3O)=CC2)OC(=O)C1

Sinonimi:

• (2S,3R,4S,5R,6S)-3,4,5-trihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• (2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[(4-methyl-2-oxo-2H-chromen-7-yl)oxy]tetrahydro-2H-pyran-2-carboxylate (non-preferred name)
• 2H-1-Benzopyran-2-one, 7-(beta-D-glucopyranuronosyloxy)-4-methyl-
• 4-Methyl-2-oxo-2H-1-benzopyran-7-yl β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• 4-Methyl-2-oxo-2H-chromen-7-yl beta-D-glucopyranosiduronic acid
• 4-Methylumbelliferone glucuronide
• 4-Methylumbelliferone β-<span class="text-smallcaps">D</span>-glucuronide
• 4-Methylumbelliferyl glucuronide
• 4-Methylumbelliferyl-Beta-D-Glucuronide
• 4-Methylumbelliferyl-β-<span class="text-smallcaps">D</span>-glucuronic acid
• 4-Mug
• Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, β-<span class="text-smallcaps">D</span>-
• Hymecromon-7-O-4-β-<span class="text-smallcaps">D</span>-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl
• β-D-Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl
• 4-Methylumbelliferyl β-D-glucuronide
• Glucopyranosiduronic acid, 4-methyl-2-oxo-2H-1-benzopyran-7-yl, β-D-

4-Methylumbelliferyl-β-D-glucuronide, 98%

CAS: 6160-80-1

It is a fluorogenic substrate for measuring of -glucoronidiase activity, for rapid sensitive identification of Escherichia coli. MUG is a substrate for glucuronidase. It is ideal for plant molecular study as a way to examine gene expression under various promoters. And while it works well for measur

Formula: C₁₆H₁₆O₉

Purezza: 98%

Colore e forma: White, Crystals or powder or crystalline powder

Peso molecolare: 352.30

Ref: 02-B21190

4-Methylumbelliferyl--D-glucuronide

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 352.2928

Ref: IN-DA003LT2

4-Methylumbelliferyl b-D-glucuronide hydrate

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉·xH₂O

Purezza: ≥ 99%

Colore e forma: White crystalline powder

Peso molecolare: 352.29 (anhydrous)

Ref: 7W-GC5027

4-Methylumbelliferyl-β-D-glucuronide trihydrate

CAS: 6160-80-1

4-Methylumbelliferyl-β-D-glucuronide trihydrate

Formula: C₁₆H₁₆O₉·3H₂O

Purezza: >98%

Colore e forma: white crystalline powder

Peso molecolare: 406.34g/mol

Ref: 54-BIMB1003

Hymecromone-β-D-Glucuronide

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉

Peso molecolare: 352.30

Ref: 4Z-H-092004

4-Methylumbelliferyl b-D-Glucuronide

Prodotto controllato

CAS: 6160-80-1

Stability Hygroscopic
Applications 4-Methylumbelliferyl β-D-Glucuronide is a substrate for glucuronidase. Also used as a test for coliform bacteria in water.Fluorescence: max. Abs. 316nm; max. Em. 375nm; e x 10-3: 12
References US Federal Register, 57, 24744 (1992)

Formula: C₁₆H₁₆O₉

Colore e forma: Neat

Peso molecolare: 352.29

Ref: TR-M334550

4-Methylumbelliferyl β-D-glucuronide Dihydrate

Prodotto controllato

CAS: 6160-80-1, 881005-91-0

Applications 4-Methylumbelliferyl β-D-glucuronide dihydrate is a useful building block and a fluorophore.
References Santocki, M.; et al.: Folia Biologia, 64, 122 (2016).

Formula: C₁₆H₁₆O₉·2H₂O

Colore e forma: Neat

Peso molecolare: 352.29

Ref: TR-M849655

4-Methylumbelliferyl β-D-glucuronide

CAS: 6160-80-1

Fluorogenic substrate for b-glucuronidase GUS

Formula: C₁₆H₁₆O₉

Purezza: Min. 95%

Peso molecolare: 352.29 g/mol

Ref: 3D-EM58443

Hymecromone-β-D-Glucuronide

CAS: 6160-80-1

Formula: C₁₆H₁₆O₉

Peso molecolare: 352.30

Ref: ST-EA-CP-H32003