CAS 6190-39-2

Mesilato di diidroergotamina

Descrizione:

Mesilato di diidroergotamina è un derivato semisintetico degli alcaloidi dell'ergot, utilizzato principalmente nel trattamento dell'emicrania e delle cefalee a grappolo. Agisce come un vasocostrittore, mirando ai recettori della serotonina per alleviare i sintomi del mal di testa. La sostanza viene tipicamente somministrata per via intranasale o endovenosa, consentendo un rapido inizio d'azione. Mesilato di diidroergotamina è caratterizzato dalla sua relativamente bassa solubilità in acqua, che può influenzare la sua formulazione e i metodi di somministrazione. La forma di sale mesilato ne migliora la stabilità e la biodisponibilità. Gli effetti collaterali comuni possono includere nausea, vertigini e potenziali effetti cardiovascolari a causa delle sue proprietà vasocostrittrici. È controindicato in pazienti con determinate condizioni cardiovascolari e deve essere usato con cautela in coloro che hanno una storia di ipertensione. Come per tutti i farmaci, è essenziale seguire le linee guida per il dosaggio e monitorare le reazioni avverse. In generale, Mesilato di diidroergotamina è un agente terapeutico prezioso nella gestione degli attacchi acuti di emicrania, offrendo sollievo a molti pazienti quando usato correttamente.

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

InChI: InChI=1S/C33H37N5O5.CH4O3S/c1-32(35-29(39)21-15-23-22-10-6-11-24-28(22)20(17-34-24)16-25(23)36(2)18-21)31(41)38-26(14-19-8-4-3-5-9-19)30(40)37-13-7-12-27(37)33(38,42)43-32;1-5(2,3)4/h3-6,8-11,17,21,23,25-27,34,42H,7,12-16,18H2,1-2H3,(H,35,39);1H3,(H,2,3,4)/t21-,23-,25-,26+,27+,32-,33+;/m1./s1

InChI key: InChIKey=ADYPXRFPBQGGAH-UMYZUSPBSA-N

SMILES: O[C@@]12N([C@@H](CC3=CC=CC=C3)C(=O)N4[C@]1(CCC4)[H])C(=O)[C@@](NC(=O)[C@@H]5C[C@@]6(C=7C=8C(C[C@]6(N(C)C5)[H])=CNC8C=CC7)[H])(C)O2.S(C)(=O)(=O)O

Sinonimi:

• (2'Ξ,5'Α,12'Ξ)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (Salt)
• (5'Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (Salt)
• (5'Alpha,10Alpha)-5'-Benzyl-12'-Hydroxy-2'-Methyl-3',6',18-Trioxo-9,10-Dihydroergotaman Methanesulfonate (1:1)
• 9,10-Dihydroergotamine mesylate
• Agit
• Angionorm
• Dergotamine
• Detms
• Dhe 45
• Diergo
• Dihydergot
• Dihydroergotamine Mesilate
• Dihydroergotamine Methanesulfonate
• Dihydroergotamine methanesulphonate
• Dihydroergotamine monomethanesulfonate
• Dihydroergotaminmesilat
• Dihytamine
• Dirgotarl
• Endophleban
• Ergomimet
• Ergont
• Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-, methanesulfonate (1:1)
• Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-, monomethanesulfonate (salt)
• Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-, methanesulfonate (1:1)
• Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-, monomethanesulfonate (salt)
• Ergotamine, 9,10-dihydro-, monomethanesulfonate (salt)
• Ergotonin
• Ikaran
• Mesilate De Dihydroergotamine
• Mesilato De Dihidroergotamina
• Migranal
• Morena
• Orstanorm
• Seglor
• Tonopres
• Verladyn
• (2'ξ,5'α,12'ξ)-5'-benzyl-12'-hydroxy-2'-methyl-3',6',18-trioxo-9,10-dihydroergotaman methanesulfonate (salt)

Dihydroergotamine methanesulfonate

CAS: 6190-39-2

Agonist at vascular serotonin receptors; partial agonist at alpha-adrenergic and dopamine D2 receptors This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aes

Formula: C₃₄H₄₁N₅O₈S

Colore e forma: Powder or crystals or crystalline powder, White to pale yellow to pale red

Peso molecolare: 679.79

Ref: 02-J63840

Dihydroergotamine Mesilate

CAS: 6190-39-2

Colore e forma: Neat

Ref: 61-FOR0808.00

DIHYDROERGOTAMINE FOR PEAK IDENTIFICATION CRS

CAS: 6190-39-2

DIHYDROERGOTAMINE FOR PEAK IDENTIFICATION CRS

Formula: C₃₄H₄₁N₅O₈S

Peso molecolare: 679.783

Ref: 41-Y0000831

DIHYDROERGOTAMINE MESILATE CRS

CAS: 6190-39-2

DIHYDROERGOTAMINE MESILATE CRS

Formula: C₃₄H₄₁N₅O₈S

Colore e forma: Crystalline Powder. White. Colourless Crystals. Powder.

Peso molecolare: 679.783

Ref: 41-D1950000

Dihydroergotamine Mesylate

CAS: 6190-39-2

Alkaloids of rye ergot and their derivatives; salts thereof, nesoi

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

Colore e forma: White Off-White Powder

Peso molecolare: 679.26758

Ref: 45-1202005

Dihydro Ergotamine Mesylate

CAS: 6190-39-2

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

Peso molecolare: 583.69 96.11

Ref: 4Z-E-614

Dihydroergotamine Mesylate

CAS: 6190-39-2

Dihydroergotamine Mesylate

Purezza: >97.0%

Ref: 54-OR1078394

Dihydroergotamine methanesulfonate salt

CAS: 6190-39-2

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

Colore e forma: White to pale-yellow or pale-red powder or crystals

Peso molecolare: 679.78

Ref: 7W-GL5120

Dihydroergotamine Mesylate

CAS: 6190-39-2

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

Purezza: >97.0%(HPLC)

Colore e forma: White to Light yellow to Light red powder to crystal

Peso molecolare: 679.79

Ref: 3B-D2633

Dihydroergotamine Mesylate

Prodotto controllato

CAS: 6190-39-2

Applications α-Androgenic blocker with selective venoconstrictor properties. Also binds to serotonin 5HT1-receptors. Antimigraine.
References de Marees, et al.: Eur. J. Clin. Pharmacol., 30, 685 (1986), McCarthy, B.G., et al.: Headache, 29, 420 (1989), Ziegler, D., et al.: Neurology, 44, 447 (1994),

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

Colore e forma: White To Off-White

Peso molecolare: 679.78

Ref: TR-D449080

Dihydro ergotamine mesylate

Prodotto controllato

CAS: 6190-39-2

Dihydroergotamine mesylate is a medication that is used in the treatment of migraines. It belongs to the group of drugs called ergot alkaloids and has been shown to have high values in cerebral metabolism. Dihydroergotamine mesylate has also been shown to have an effect on dopamine levels in human serum, which may be due to its ability to inhibit neuronal death. Dihydroergotamine mesylate is administered intravenously, orally or intramuscularly for the treatment of acute migraine attacks. The drug can also be given rectally for the prevention of chronic migraine episodes. This drug may cause side effects such as nausea, vomiting and dizziness.

Formula: C₃₄H₄₁N₅O₈S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 679.78 g/mol

Ref: 3D-FD21918

Dihydroer GOtamine mesylate

CAS: 6190-39-2

Formula: C₃₄H₃₉N₅O₇S

Colore e forma: Solid

Peso molecolare: 661.7678

Ref: IN-DA003PIX

Dihydroergotamine mesylate

Prodotto controllato

CAS: 6190-39-2

Formula: C₃₃H₃₇N₅O₅·CH₄O₃S

Colore e forma: Neat

Peso molecolare: 679.78

Ref: 04-C12634549