CAS 624-49-7

Fumarato di dimetile

Descrizione:

Fumarato di dimetile (DMF) è un composto organico con la formula molecolare C6H8O4, classificato come un estere di fumarato. Appare come un solido cristallino bianco a temperatura ambiente ed è noto per la sua solubilità in solventi polari come acqua, metanolo ed etanolo. Il DMF è caratterizzato dal suo legame doppio tra gli atomi di carbonio nella parte di fumarato, che contribuisce alla sua reattività e potenziali applicazioni. È utilizzato principalmente nell'industria farmaceutica, in particolare come trattamento per la sclerosi multipla, dove agisce come un immunomodulatore. Inoltre, il DMF ha applicazioni nella produzione di polimeri e come potenziale agente terapeutico in varie condizioni infiammatorie. Il composto è generalmente considerato a bassa tossicità, ma può causare irritazione della pelle e altri effetti avversi in caso di esposizione. La sua stabilità in condizioni normali lo rende adatto per varie formulazioni, anche se deve essere maneggiato con cura per evitare degradazione o reazioni indesiderate.

Formula: C₆H₈O₄

InChI: InChI=1S/C6H8O4/c1-9-5(7)3-4-6(8)10-2/h3-4H,1-2H3/b4-3+

InChI key: InChIKey=LDCRTTXIJACKKU-ONEGZZNKSA-N

SMILES: C(/C=C/C(OC)=O)(OC)=O

Sinonimi:

• (2E)-2-Butenedioic acid dimethyl ester
• (E)-2-Butenedioic acid dimethyl ester
• (E)-But-2-enedioic acid dimethyl ester
• 2-Butenedioic acid (2E)-, 1,4-dimethyl ester
• 2-Butenedioic acid (2E)-, dimethyl ester
• 2-Butenedioic acid (E)-, dimethyl ester
• Allomaleic acid dimethyl ester
• Azl-O 211089
• Bg 00012
• Bg 12
• Boletic acid dimethyl ester
• Dimethyl (E)-2-butenedioate
• Dimethyl (E)-butenedioate
• Dimethyl trans-ethylenedicarboxylate
• Dimethylfumarat
• Dimethylfumarate
• Fumarate De Dimethyle
• Fumarate, Dimethyl
• Fumarato De Dimetilo
• Fumaric acid, dimethyl ester
• Fumarsaeure-Dimethylester
• Methyl fumarate
• Nsc 167432
• Nsc 25942
• Panaclar
• Skilarence
• Tecfidera
• Tecfira
• dimethyl (2E)-but-2-enedioate
• trans-1,2-Ethylenedicarboxylic acid dimethyl ester

Dimethyl Fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purezza: >98.0%(GC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 144.13

Ref: 3B-F0069

Dimethyl Fumarate

CAS: 624-49-7

Colore e forma: White

Ref: 61-FOR3170.00

Dimethyl Fumarate

CAS: 624-49-7

Acyclic polycarboxylic acids and their anhydrides, halides, peroxides and their derivatives, nesoi

Formula: C₆H₈O₄

Colore e forma: White Powder

Peso molecolare: 144.04226

Ref: 45-1210218

(E)-Dimethyl fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 144.1253

Ref: IN-DA003PM2

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate

Purezza: ≥90%

Peso molecolare: 144.13g/mol

Ref: 54-BUP18658

Dimethyl Fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 144.13

Ref: 4Z-F-551

Dimethyl fumarate, min. 99%

CAS: 624-49-7

Formula: C₆H₈O₄

Purezza: min. 99%

Colore e forma: White to off-white crystalline solid

Peso molecolare: 144.12

Ref: 08-06-0040

Dimethyl Fumarate

Prodotto controllato

CAS: 624-49-7

Formula: C₆H₈O₄

Colore e forma: Neat

Peso molecolare: 144.13

Ref: 86-MM3170.00

Fumaric acid-dimethyl ester

CAS: 624-49-7

Formula: C₆H₈O₄

Colore e forma: Neat

Peso molecolare: 144.13

Ref: 04-C13955800

DIMETHYL FUMARATE

CAS: 624-49-7

Purezza: 98%

Peso molecolare: 144.126007080078

Ref: 10-F794923

Fumaric acid-dimethyl ester 1000 µg/mL in Acetonitrile

CAS: 624-49-7

Formula: C₆H₈O₄

Colore e forma: Single Solution

Peso molecolare: 144.13

Ref: 04-A13955800AL-1000

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate

Purezza: 99%

Peso molecolare: 144.13g/mol

Ref: 54-OR9602

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate (DMF) is an orally Nrf2 activator. Dimethyl fumarate has antimicrobial and anti-inflammatory activities. Cost-effective and quality-assured.

Formula: C₆H₈O₄

Purezza: 90.51% - >99.99%

Colore e forma: White To Off-White Powder White Crystalline Powder

Peso molecolare: 144.13

Ref: TM-T0492

Dimethyl fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purezza: ≥ 98.5% (anhydrous basis)

Colore e forma: White crystalline powder or crystals

Peso molecolare: 144.13

Ref: 7W-GK0623

Dimethyl Fumarate

CAS: 624-49-7

Applications Dimethyl fumarate is the methyl ester form of Fumaric Acid (F500380), and is a compound used as a treatment for the relapsing forms of multiple sclerosis and psoriasis. Dimethyl fumarate is effective in treating multiple sclerosis by mediating the activation of the nuclear 1 factor (Nrf2) antioxidant response pathway, resulting in neuroprotective effects. Dimethyl fumarate is also used in cycloaddition reactions involving ylides, benzenes and amino acids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Albrecht, P., et al.: J. Neuroinflammation, 9, 2094 (2012); Chen, X. et al.: J. Am. Chem. Soc., 130, 5652 (2008); Gold, R., et al.: New Engl. J Med., 367, 1098 (2012); Gothelf, A. et al.: Angew. Chem., Int. Ed., 41, 4236 (2002); Schmidt, T., et al.: Bioorg. Med. Chem., 15, 333 (2007)

Formula: C₆H₈O₄

Colore e forma: White

Peso molecolare: 144.13

Ref: TR-D464965

Dimethyl fumarate

CAS: 624-49-7

Dimethyl fumarate (DMF) is a drug that acts as a prodrug for the active metabolite monomethyl fumarate (MMF). It is used in the treatment of psoriasis and other skin diseases, including erythema nodosum leprosum. DMF has been shown to significantly up-regulate the expression of proliferating cell nuclear antigen (PCNA), which is a response element for pdgf-bb. DMF also has antioxidant properties, which may be due to its ability to inhibit reactive oxygen species production. This drug also inhibits the activity of certain enzymes and blocks drug transporters that are involved in bowel disease.

Formula: C₆H₈O₄

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 144.13 g/mol

Ref: 3D-FD15538

Dimethyl fumarate, 99%

CAS: 624-49-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₈O₄

Purezza: 99%

Colore e forma: Crystals or crystalline powder or flakes, White to cream to pale brown

Peso molecolare: 144.13

Ref: 02-A10402

Dimethyl fumarate

CAS: 624-49-7

Formula: C₆H₈O₄

Purezza: 99.0 min. %

Colore e forma: White to off-white crystalline solid

Peso molecolare: 144.12

Ref: 08-D033