CAS 63-89-8

1,2-Dipalmitoil-sn-glicero-3-fosfocolina

Descrizione:

1,2-Dipalmitoil-sn-glicero-3-fosfocolina (DPPC) è un fosfolipide comunemente usato in biochimica e biofisica, in particolare in studi che coinvolgono membrane cellulari e liposomi. È caratterizzato dalle sue due catene di acido palmitico, che sono acidi grassi saturi, contribuendo alla sua stabilità strutturale e rigidità a temperature fisiologiche. Il DPPC ha uno scheletro di glicerolo con un gruppo fosfato attaccato al terzo carbonio, che è ulteriormente legato a un gruppo colina, rendendolo una molecola zwitterionica. Questa struttura unica consente al DPPC di formare bilayer in ambienti acquosi, mimando membrane biologiche. Mostra una temperatura di transizione di fase, al di sotto della quale si trova in uno stato gelatinoso e al di sopra della quale transita a uno stato fluido, influenzando la fluidità e la permeabilità della membrana. Il DPPC è anche utilizzato in sistemi di somministrazione di farmaci e come tensioattivo in varie formulazioni farmaceutiche grazie alla sua capacità di stabilizzare emulsioni e migliorare la solubilità di composti idrofobici. Il suo numero CAS è 63-89-8, che indica la sua identificazione unica nei database chimici.

Formula: C₄₀H₈₀NO₈P

InChI: InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

InChI key: InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N

SMILES: [C@H](OC(CCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O

Sinonimi:

• (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid
• (R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide
• (R)-2,3-Bis(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
• 1,2-<span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylcholine
• 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
• 1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phophocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dihexadecanoyl-sn-glycerol-3-phosphorylcholine
• 1,2-Dipalmitoyl-3-Sn-Phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-3-phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-lecithin
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-lecithin
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• 1,2-Dipalmitoyl-L-3-phosphatidylcholine
• 1,2-Dipalmitoyl-L-lecithin
• 1,2-Dipalmitoyl-L-phosphatidylcholine
• 1,2-Dipalmitoyl-L-α-lecithin
• 1,2-Dipalmitoyl-L-α-phosphatidylcholine
• 1,2-Dipalmitoyl-sn-3-glycerophosphocholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate
• 1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dipalmitoyl-sn-glycerol-3-phosphocholine
• 1,2-Dipalmitoyl-sn-glycerophosphocholine
• 1,2-Dipalmitoyl-sn-glycerophosphorylcholine
• 1,2-Dipalmitoyl-sn-glyceryl-3-phosphocholine
• 1,2-Dipalmitoyl-sn-phosphatidylcholine
• 1,2-Dipalmitoylglycero-3-phosphocholine
• 1,2-Dispalmitoyl-sn-phosphatidylcholine
• 1,2-L-α-Dipalmitoylphosphatidylcholine
• 1,2-Palmitoyl-sn-glycero-3-phosphocholine
• 1,2-dipalmitoyl-L-alpha-phosphatidylcholine
• 129Y83
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, hydroxide, inner salt, 4-oxide, (R)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (R)-
• 4-oxido de (R)-(4-oxido-10-oxo-7-palmitoil-3,5,9-trioxa-4-fosfapentacosil)trimetilamonio
• 4-oxyde de (R)-(4-oxydo-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium
• 55: PN: WO2017201317 SEQID: 128 claimed RNA
• <span class="text-smallcaps">L</span>-1,2-Dipalmitoyl-α-lecithin
• <span class="text-smallcaps">L</span>-1,2-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-DPPC
• <span class="text-smallcaps">L</span>-Dipalmitoyl lecithin
• <span class="text-smallcaps">L</span>-Dipalmitoyl phosphatidylcholine
• <span class="text-smallcaps">L</span>-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-1,2-Dipalmitoyl lecithin
• <span class="text-smallcaps">L</span>-α-DPPC
• <span class="text-smallcaps">L</span>-α-Dipalmitoylecithin
• <span class="text-smallcaps">L</span>-α-Dipalmitoyllecithin
• <span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-Lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-phosphatidylcholine
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoylphosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipalmitin, <span class="text-smallcaps">L</span>-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipalmitin, L-
• Colfosceril Palmitate
• Dihexadecanoyl-sn-glycero-3-phosphocholine
• Dipalmitoyl L-α-phosphatidylcholine
• Dipalmitoyl-<span class="text-smallcaps">L</span>-3-glycerylphosphorylcholine
• Dipalmitoyl-<span class="text-smallcaps">L</span>-lecithin
• Dipalmitoyl-<span class="text-smallcaps">L</span>-α-lecithin
• Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• Dipalmitoyl-L-3-glycerylphosphorylcholine
• Dipalmitoyl-L-α-lecithin
• Dipalmitoyl-sn-3-phosphatidylcholine
• Dipalmitoyl-sn-glycero-3-phosphocholine
• Dipalmitoylphosphatidylcholine
• Dppc
• L-1,2-Dipalmitoyl-α-lecithin
• L-1,2-Dipalmitoylphosphatidylcholine
• L-A-phosphatidylcholine dipalmitoyl*synthetic
• L-Dipalmitoyl lecithin
• L-Dppc
• L-a-Dipalmitoyl Lecithin
• L-a-Lecitin-dipalmitoyl
• L-α-1,2-Dipalmitoyl lecithin
• L-α-DPPC
• L-α-Dipalmitoylecithin
• L-α-Dipalmitoyllecithin
• L-α-Dipalmitoylphosphatidylcholine
• L-α-Lecithin
• L-β,γ-Dipalmitoyl-α-lecithin
• L-β,γ-Dipalmitoyl-α-phosphatidylcholine
• L-β,γ-Dipalmitoylphosphatidylcholine
• Palmitin, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-
• [(2R)-2,3-Di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• sn-3-Dipalmitoyllecithin
• β,γ-Dipalmitoyl <span class="text-smallcaps">L</span>-α-phosphatidylcholine
• β,γ-Dipalmitoyl L-α-phosphatidylcholine
• β,γ-Dipalmitoyl-<span class="text-smallcaps">L</span>-(α)-lecithin
• β,γ-Dipalmitoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• β,γ-Dipalmitoyl-L-(α)-lecithin
• β,γ-Dipalmitoyl-L-phosphatidylcholine

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Formula: C₄₀H₈₀NO₈P

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 734.05

Ref: 3B-D3925

DPPC

CAS: 63-89-8

Purezza: 97%

Peso molecolare: 734.052978515625

Ref: 10-F601359

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Bachem ID: 4004249.

Formula: C₄₀H₈₀NO₈P

Purezza: > 99%

Colore e forma: White Powder

Peso molecolare: 734.05

Ref: 01-4004249

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

Formula: C₄₀H₈₀NO₈P

Purezza: By hplc: 98% (Typical Value in Batch COA)

Colore e forma: white solid

Peso molecolare: 734.04g/mol

Ref: 54-BIB6043

DPPC

CAS: 63-89-8

DPPC

Purezza: ≥98%

Peso molecolare: 734.04g/mol

Ref: 54-BUP15935

DPPC (Dipalmitoylphosphatidylcholine)

CAS: 63-89-8

Formula: C₄₀H₈₀NO₈P

Colore e forma: White To Off-White Solid

Peso molecolare: 734.05

Ref: 4Z-C-594

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Formula: C₄₀H₈₀NO₈P

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 734.04

Ref: 7W-GL3400

1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 63-89-8

Formula: C40H80NO8P

Purezza: >99%

Colore e forma: Solid

Peso molecolare: 734.04

Ref: 48-37-1600

Succinyl Monocholine-d4 Chloride

CAS: 63-89-8

Formula: C₉H₁₄D₄ClNO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 243.72

Ref: 4Z-C-5947

DPPC

CAS: 63-89-8

DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.

Formula: C₄₀H₈₀NO₈P

Purezza: 99.33% - 99.5%

Colore e forma: Solid

Peso molecolare: 734.04

Ref: TM-T7773

1,​2-​Dipalmitoyl-​sn-​glycero-​3-​phosphocholine (Colfosceril Palmitate)

Prodotto controllato

CAS: 63-89-8

Stability Hygroscopic
Applications Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),

Formula: C₄₀H₈₀NO₈P

Colore e forma: Neat

Peso molecolare: 734.04

Ref: TR-C640500

Colfosceril-d9 Palmitate

Prodotto controllato

CAS: 63-89-8

Applications Labelled Colfosceril Palmitate (C640500). Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),

Formula: C₄₀D₉H₇₁NO₈P

Colore e forma: Neat

Peso molecolare: 743.094

Ref: TR-C640502

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) is a sodium salt that has the ability to form surfactant bilayers. DPPC is a model system for studying biochemical reactions and the phase transition of lipid bilayers. This compound has been used to study the effects of various drugs on cell membranes in biochemical research. In addition, DPPC has been shown to have hypoglycemic effects in animal models as well as having an anti-inflammatory effect.

Formula: C₄₀H₈₀NO₈P

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 734.04 g/mol

Ref: 3D-FD46765