CAS 63-92-3

Cloridrato di fenossibenzamina

Descrizione:

Cloridrato di fenossibenzamina è un antagonista alfa-adrenergico non selettivo utilizzato principalmente nel trattamento di condizioni come il feocromocitoma, un tipo di tumore che può causare un'eccessiva liberazione di catecolamine. È caratterizzato dalla sua capacità di legarsi in modo irreversibile ai recettori alfa-adrenergici, portando a una vasodilatazione prolungata e a una diminuzione della pressione sanguigna. Il composto viene tipicamente somministrato per via orale ed è noto per la sua durata d'azione relativamente lunga grazie al suo meccanismo di legame irreversibile. Cloridrato di fenossibenzamina è una polvere cristallina bianca o quasi bianca, solubile in acqua e alcol, e ha un intervallo di pH che è generalmente neutro. I suoi effetti farmacologici possono includere effetti collaterali come ipotensione ortostatica, tachicardia e congestione nasale. A causa del suo meccanismo d'azione, è importante monitorare attentamente i pazienti per le risposte cardiovascolari. Come con qualsiasi farmaco, deve essere utilizzato sotto la guida di un professionista sanitario, considerando possibili interazioni e controindicazioni.

Formula: C₁₈H₂₂ClNO·ClH

InChI: InChI=1S/C18H22ClNO.ClH/c1-16(15-21-18-10-6-3-7-11-18)20(13-12-19)14-17-8-4-2-5-9-17;/h2-11,16H,12-15H2,1H3;1H

InChI key: InChIKey=VBCPVIWPDJVHAN-UHFFFAOYSA-N

SMILES: C(N(C(COC1=CC=CC=C1)C)CCCl)C2=CC=CC=C2.Cl

Sinonimi:

• 2-(N-benzyl-2-chloroethylamino)-1-phenoxypropane hydrochloride
• Bensylyt Nen
• Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
• Benzenemethanamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride (1:1)
• Benzyl(2-Chloroethyl)(1-Methyl-2-Phenoxyethyl)Amine Hydrochloride
• Benzylamine, N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)-, hydrochloride
• Dibenzylin
• Dibenzyline chloride
• Dibenzyline hydrochloride
• Dibenzyran
• Fenoxybenzamin
• N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzenemethanamine hydrochloride
• N-(2-chloroethyl)-N-(1-methyl-2-phenoxyethyl)benzylamine hydrochloride
• N-2-Phenoxyisopropyl-N-benzyl-β-chloroethylamine hydrochloride
• N-2-phenoxyisopropyl-N-benzyl-chloroethylamine hydrochloride
• N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium
• N-benzyl-N-(2-chloroethyl)-1-phenoxypropan-2-aminium chloride
• N-phenoxyisopropyl-N-benzyl-beta-chloroethylamine hydrochloride
• NSC 37448
• Phenoxybenzamide Hydrochloride
• Phenoxybenzamide, HCl
• Phenoxybenzamine HCL

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Formula: C₁₈H₂₂ClNO·HCl

Purezza: >98.0%(T)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 340.29

Ref: 3B-D0158

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Selective alpha adrenergic blocking agent. Irreversible calmodulin inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or

Formula: C₁₈H₂₃Cl₂NO

Colore e forma: White to off-white, Powder

Peso molecolare: 340.29

Ref: 02-J61900

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Colore e forma: Neat

Ref: 61-FOR0778.00

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride

Formula: C₁₈H₂₂CINOHCl

Purezza: 97.0%

Colore e forma: White

Peso molecolare: 443.05129

Ref: 47-1072

PHENOXYBENZAMINE HYDROCHLORIDE CRS

CAS: 63-92-3

PHENOXYBENZAMINE HYDROCHLORIDE CRS

Ref: 41-Y0002282

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Aromatic drugs of amino-alcohols, other than those contg > one kind of oxygen function, their ethers and esters; salts thereof, nesoi

Formula: C₁₈H₂₂ClNO·HCI

Colore e forma: White Off-White Powder

Peso molecolare: 340.29 g/mol

Ref: 45-1526007

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride: non-selective, irreversible alpha-blocker; antihypertensive, vasodilator, may cause tachycardia, potential carcinogen.

Formula: C₁₈H₂₃Cl₂NO

Purezza: 98.04% - >99.99%

Colore e forma: Antihypertensive Drug

Peso molecolare: 340.3

Ref: TM-T1158

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Formula: C₁₈H₂₂ClNO·HCl

Peso molecolare: 340.29

Ref: 7W-GL1636

Phenoxybenzamine HCl

CAS: 63-92-3

Formula: C₁₈H₂₂ClNO·HCl

Peso molecolare: 303.83 36.46

Ref: 4Z-P-0812

Phenoxybenzamine HCl

CAS: 63-92-3

Phenoxybenzamine HCl

Purezza: 98%

Peso molecolare: 340.30g/mol

Ref: 54-OR1014632

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride

Purezza: ≥98%

Peso molecolare: 340.3g/mol

Ref: 54-BUP18326

Phenoxybenzamine Hydrochloride

CAS: 63-92-3

Formula: C₁₈H₂₂ClNO·ClH

Colore e forma: Neat

Peso molecolare: 340.29

Ref: 86-MM0778.00

Phenoxybenzamine hydrochloride

CAS: 63-92-3

Phenoxybenzamine hydrochloride is a drug with pharmacological properties, which is used in the treatment of carcinoid syndrome. It is a combination therapy group that can be used to treat patients with neurological disorders. Phenoxybenzamine inhibits the activity of the 5-HT2 receptors and has been shown to reduce neuronal death. In addition, it has been shown to increase chemiluminescence in cells infected with HIV. Phenoxybenzamine also has effects on cardiac function and can be used to treat congestive heart failure as well as high levels of natriuretic peptides in maternal blood during pregnancy. It has also been shown to be effective against infectious diseases, such as tuberculosis and malaria.

Formula: C₁₈H₂₃Cl₂NO

Purezza: Min. 90 Area-%

Colore e forma: Powder

Peso molecolare: 340.29 g/mol

Ref: 3D-FP26891

Phenoxybenzamine.HCl

CAS: 63-92-3

M02323 - Phenoxybenzamine.HCl

Formula: C₁₈H₂₃Cl₂NO

Purezza: 98%+(HPLC);RG

Colore e forma: Solid

Peso molecolare: 340.29

Ref: 10-M02323

Phenoxybenzamine Hydrochloride

Prodotto controllato

CAS: 63-92-3

Applications An irreversible α-antagonist. Used in the treatment of hypertension, it has a relatively slow onset and prolonged effect when compared to alternative α-blockers.
References Glass, B., et al.: J. Pharm. Pharm. Sci., 9, 398 (2006), Huang, R., et al.: Chem. Res. Toxicol., 21, 659 (2008), Gohil, V., et al.: Nat. Biotechnol., 28, 249 (2010),

Formula: C₁₈H₂₂ClNO·ClH

Colore e forma: Neat

Peso molecolare: 340.29

Ref: TR-P227990