CAS 63234-80-0

3-(2-cloroetil)-6,7,8,9-tetraidro-2-metil-4H-pirido[1,2-a]pirimidin-4-one

Descrizione:

3-(2-cloroetil)-6,7,8,9-tetraidro-2-metil-4H-pirido[1,2-a]pirimidin-4-one, con il numero CAS 63234-80-0, è un composto chimico che appartiene alla classe delle pirido-pirimidine. Questa sostanza presenta una complessa struttura biciclica che include un anello di piridina e un anello di pirimidina, contribuendo alle sue uniche proprietà chimiche. La presenza di un gruppo cloroetile aumenta la sua reattività, rendendolo potenzialmente utile in varie reazioni chimiche, comprese le sostituzioni nucleofile. La configurazione tetraidro indica che il composto è saturo in alcune posizioni, il che può influenzare la sua attività biologica e solubilità. Inoltre, il gruppo metile attaccato all'anello di piridina può influenzare le proprietà steriche ed elettroniche del composto. Questo composto può mostrare attività farmacologiche, sebbene siano necessari dati biologici specifici per accertare le sue potenziali applicazioni in chimica medicinale. In generale, le sue caratteristiche strutturali suggeriscono che potrebbe essere di interesse nello sviluppo di nuovi agenti terapeutici o come blocco di costruzione nella sintesi organica.

Formula: C₁₁H₁₅ClN₂O

InChI: InChI=1/C11H15ClN2O/c1-8-9(5-6-12)11(15)14-7-3-2-4-10(14)13-8/h2-7H2,1H3

InChI key: InChIKey=CMWCQQUYLPYOMY-UHFFFAOYSA-N

SMILES: O=C1N2C(=NC(C)=C1CCCl)CCCC2

Sinonimi:

• 3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido-(1,2-A) Pyrimidin-4-One
• 4H-Pyrido[1,2-a]pyrimidin-4-one, 3-(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-
• 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one
• 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-A]pyrimidin-4-one
• 3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2
• 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]-pyrididine-4-one (intermediate of Risperidone)
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]-PYRIMIDIN-4-ONE(RISPERIDONEINTERMEDIATE)
• -a]pyrimidin-4-one
• 3-2(2-chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-alpha]pyrimnidin-4-one
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDINO[1,2-A]PYRIMIDINE-4-ONE
• 8-(CHLOROETHYL)-9-METHYL-6,10-DIAZABICYCLO[4.4.0]DECA-8,10-DIEN-7-ONE
• 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1, 2-A]-PYRIMIDIN-4-ONE ( RISPERIDONE INTERMEDIATE ).
• 3-2(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO[1,2-A]PYRIMDIN-4-ONE
• 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-A]-PYRIDIDINE-4-ONE
• 3-(2-CHLORO-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]PYRIMIDIN-4-ONE
• 3-(2-Chloroethyl)-2-Methyl-6,7,8,9-tetrahydro-4H-pyrimidine-4-one
• 3-(2-CHLOROETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-4H-PYRIDO[1,2-ALPHA]PYRIMIDIN-4-ONE
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRLDO[1,2-A]PYRIMDIN-4-ONE
• 3-(2-CHLOROETHYL)-6,7,8,9-TETRAHYDRO-2-METHYL-4H-PYRIDO(1,2A)PYRIMIDINE-4-ONE

3-(2-Chloroethyl)-6,7,8,9-tetrahydro-2-methyl-4H-pyrido[1,2-a]pyrimidin-4-one

CAS: 63234-80-0

Formula: C₁₁H₁₅ClN₂O

Purezza: >98.0%(GC)(T)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 226.70

Ref: 3B-C2433

Risperidone Pyridopyrimidinone Analog (3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one)

CAS: 63234-80-0

Compounds containing a pyrimidine ring, whether or not hydrogenated, or piperazine ring in the structure, nesoi

Formula: C₁₁H₁₅ClN₂O

Colore e forma: Off-White Solid

Peso molecolare: 226.08729

Ref: 45-1A11420

Risperidone EP Impurity L

CAS: 63234-80-0

Formula: C₁₁H₁₅ClN₂O

Colore e forma: White To Off-White Solid

Peso molecolare: 226.70

Ref: 4Z-R-0633

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One

CAS: 63234-80-0

3-(2-Chloroethyl)-6,7,8,9-Tetrahydro-2-Methyl-4H-Pyrido[1,2-a]Pyrimidin-4-One

Purezza: 98%

Peso molecolare: 226.70g/mol

Ref: 54-OR1010638

Risperidone EP Impurity L

CAS: 63234-80-0

Formula: C₁₁H₁₅ClN₂O

Peso molecolare: 263.16

Ref: ST-EA-CP-R15012

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

Prodotto controllato

CAS: 63234-80-0

Impurity Risperidone EP Impurity L
Applications 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one (Risperidone EP Impurity L) is an intermediate in the synthesis of Risperidone (R525000), which is a combined serotonin (5-HT2) and dopamine (D2) receptor antagonist.
References Jannssen, P.A.J., et al.: J. Pharmacol. Exp. Ther., 244, 685 (1988), Gelders, Y.G., et al.: Pharmacopsychiatry, 23, 206 (1990), Green, B.: Curr. Med. Res. Opin., 16, 57 (2000)

Formula: C₁₁H₁₅ClN₂O

Colore e forma: Neat

Peso molecolare: 226.70

Ref: TR-C366155

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS: 63234-80-0

3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4-one is an antibacterial agent that inhibits bacterial growth by binding to the 50S ribosomal subunit. It is a white crystalline powder that is soluble in methanol and acetonitrile. 3-(2-Chloroethyl)-2-methyl-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidin-4 - one binds to the ribosome and interferes with protein synthesis by inhibiting the release of aminoacyl tRNA from the ribosome. The drug has been shown to have antibacterial activity against Gram positive and Gram negative bacteria. 3-(2) Chloroethyl)-2-methyl 6,7

Formula: C₁₁H₁₅ClN₂O

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 226.7 g/mol

Ref: 3D-FC20229

3-(2-CHLORO-ETHYL)-2-METHYL-6,7,8,9-TETRAHYDRO-PYRIDO[1,2-A]PYRIMIDIN-4-ONE

CAS: 63234-80-0

Formula: C₁₁H₁₅ClN₂O

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 226.7

Ref: 10-F300981