CAS 64-72-2

Clortetraciclina cloridrato

Descrizione:

Clortetraciclina cloridrato è un antibiotico ad ampio spettro appartenente alla classe delle tetracicline, utilizzato principalmente in medicina veterinaria e in alcune applicazioni umane. È caratterizzato dalla sua apparente cristallina gialla ed è solubile in acqua, il che facilita il suo utilizzo in varie formulazioni. Il composto presenta proprietà antibatteriche inibendo la sintesi proteica nei batteri, rendendolo efficace contro un'ampia gamma di organismi Gram-positivi e Gram-negativi. Clortetraciclina cloridrato è spesso utilizzato nel trattamento delle infezioni, così come in contesti agricoli per promuovere la crescita del bestiame. Il suo meccanismo d'azione implica il legame con la subunità ribosomiale 30S, impedendo l'attacco dell'aminoacil-tRNA, interrompendo così il processo di traduzione. Sebbene generalmente ben tollerato, può causare effetti collaterali come disturbi gastrointestinali e fotosensibilità. Inoltre, l'uso delle tetracicline ha sollevato preoccupazioni riguardo alla resistenza agli antibiotici, rendendo necessaria una considerazione attenta della sua applicazione sia in medicina umana che veterinaria.

Formula: C₂₂H₂₃ClN₂O₈·ClH

InChI: InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15-,21-,22-;/m0./s1

InChI key: InChIKey=CBHYYLPALVVVEY-MRFRVZCGSA-N

SMILES: O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C([C@@]3(C)O)=C(Cl)C=CC4O)[H])[H].Cl

Sinonimi:

• (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• (2Z,4S,4aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
• 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
• 7-Chlorotetracycline hydrochloride
• 7-Chlorotetracycline monohydrochloride
• Aureociclina
• Aureocycline
• Aureomycin monohydrochloride
• Aureovit 12C80
• Aurofac 100
• Biomycin hydrochloride
• Chlortetracycline hydrochloride
• Chlortetracyclinium chloride
• Fermycin Soluble
• Isphamycin

Chlortetracycline-13C-d3 Hydrochloride (Technical Grade, may contain up to 1.5% d0)

Prodotto controllato

CAS: 64-72-2

Formula: C₂₁CH₂₀D₃ClN₂O₈·HCl

Colore e forma: Neat

Peso molecolare: 534.386

Ref: TR-C426510

Chlortetracycline Hydrochloride

Prodotto controllato

CAS: 64-72-2

Applications Chlortetracycline is an antibiotic substance isolated from the substrate of Streptomyces aureofaciens. Chlortetracycline is an antimicrobial and antibacterial.Chlortetracycline contains an undetermined amount of epi-chlortetracycline.
References Skaletzki, B., et al.: Pharmazie, 29, 424 (1974), Martinez, M., et al.: Biochemistry, 40, 11965 (2001), Davidson, P., et al.: Food Technol., 55, 69 (2002), de la Fuente, R., et al.: Br. J. Pharmacol., 149, 551 (2006),

Formula: C₂₂H₂₃ClN₂O₈·ClH

Colore e forma: Neat

Peso molecolare: 515.34

Ref: TR-C426500

Chlortetracycline-13C-d3 Hydrochloride (Technical Grade)

Prodotto controllato

CAS: 64-72-2

Applications Chlortetracycline-13C-d3 Hydrochloride is a labelled analog of Chlortetracycline Hydrochloride (C426500), which is an antibiotic substance isolated from the substrate of Streptomyces aureofaciens. Chlortetracycline is an antimicrobial and antibacterial.
References Skaletzki, B., et al.: Pharmazie, 29, 424 (1974), Martinez, M., et al.: Biochemistry, 40, 11965 (2001), Davidson, P., et al.: Food Technol., 55, 69 (2002), de la Fuente, R., et al.: Br. J. Pharmacol., 149, 551 (2006),

Formula: C₂₁CH₂₀D₃ClN₂O₈·HCl

Colore e forma: Neat

Peso molecolare: 519.35

Ref: TR-C426504

Chlorotetracycline monohydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-72-2

Chlorotetracycline monohydrochloride is an antibiotic designed for culture media use. It is derived from the bacterium *Streptomyces aureofaciens*, and functions primarily by inhibiting bacterial protein synthesis. This action prevents the attachment of aminoacyl-tRNA to the ribosomal acceptor site, effectively halting the growth of bacteria by disrupting protein production, which is essential for their survival and replication.

Formula: C₂₂H₂₄Cl₂N₂O₈

Purezza: (Chlortetracycline Hcl) Min. 89.5%

Peso molecolare: 515.34 g/mol

Ref: 3D-C-5490

Chlorotetracycline monohydrochloride, Antibiotic for Culture Media Use Only

CAS: 64-72-2

Chlorotetracycline monohydrochloride is an antibiotic compound specifically designed for culture media use. It is derived from a naturally occurring tetracycline produced by the bacterium *Streptomyces aureofaciens*. As a broad-spectrum antibiotic, chlorotetracycline functions by inhibiting protein synthesis in susceptible bacteria. It binds to the 30S subunit of the bacterial ribosome, blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor site, which effectively halts translational elongation.

Formula: C₂₂H₂₄Cl₂N₂O₈

Purezza: (Chlortetracycline Hcl) Min. 89.5%

Colore e forma: Yellow Powder

Peso molecolare: 515.34 g/mol

Ref: 3D-AC162429

Chlortetracycline hydrochloride

CAS: 64-72-2

Chlortetracycline hydrochloride is a broad-spectrum antibiotic, which is derived from the bacterium *Streptomyces aureofaciens*. It operates by inhibiting protein synthesis in susceptible bacteria through binding to the 30S ribosomal subunit. This mechanism effectively blocks the attachment of aminoacyl-tRNA to the mRNA-ribosome complex, thereby preventing the addition of new amino acids to the nascent peptide chain.

Formula: C₂₂H₂₄Cl₂N₂O₈

Purezza: Min. 89.5%

Colore e forma: Yellow Powder

Peso molecolare: 515.34 g/mol

Ref: 3D-AC20413

Lymecycline EP Impurity G

CAS: 64-72-2

Formula: C₂₂H₂₃ClN₂O₈HCl

Peso molecolare: 478.88 : 36.46

Ref: ST-EA-CP-L64007