CAS 641-38-3

Alternariol

Descrizione:

Alternariol è una micotossina prodotta da varie specie del fungo Alternaria, comunemente trovata in materiale vegetale in decomposizione e in alcuni prodotti alimentari. È classificata come un composto fenolico ed è nota per i suoi potenziali effetti tossicologici, inclusa la mutagenicità e la citotossicità. La struttura molecolare di Alternariol presenta un gruppo idrossile e un anello di lattone, contribuendo alla sua reattività chimica e attività biologica. Questo composto è spesso studiato per le sue implicazioni nella sicurezza alimentare, poiché può contaminare colture come pomodori, frutta e cereali, ponendo rischi per la salute dei consumatori. Oltre alle sue proprietà tossicologiche, Alternariol è stata indagata per le sue potenziali attività antiossidanti, sebbene il suo profilo di sicurezza rimanga una preoccupazione. Le agenzie regolatorie monitorano i suoi livelli nei prodotti alimentari per garantire la sicurezza dei consumatori, e la ricerca in corso mira a comprendere meglio i suoi meccanismi d'azione e gli effetti sulla salute umana. In generale, Alternariol esemplifica la complessa interazione tra tossine naturali e sicurezza alimentare.

Formula: C₁₄H₁₀O₅

InChI: InChI=1S/C14H10O5/c1-6-2-7(15)5-11-12(6)9-3-8(16)4-10(17)13(9)14(18)19-11/h2-5,15-17H,1H3

InChI key: InChIKey=CEBXXEKPIIDJHL-UHFFFAOYSA-N

SMILES: CC1=C2C=3C(C(=O)OC2=CC(O)=C1)=C(O)C=C(O)C3

Sinonimi:

• 3,4,4'-Trihydroxy-6'-methyl-2-biphenylcarboxylic acid, gamma lactone
• 3,7,9-Trihydroxy-1-Methyl-Benzo[C]Chromen-6-One
• 3,7,9-Trihydroxy-1-methyl-6H-dibenzo[b,d]pyran-6-one
• 3,7,9-Trihydroxy-1-methylbenzo[c]chromen-6-one
• 6H-Dibenzo(b,d)pyran-6-one, 1-methyl-3,7,9-trihydroxy-
• 6H-Dibenzo[b,d]pyran-6-one, 3,7,9-trihydroxy-1-methyl-
• AOH
• Alternariol
• Brn 0244839
• Ccris 6734
• NSC 638263

Alternariol

CAS: 641-38-3

Alternariol

Formula: C₁₄H₁₀O₅

Purezza: 99%

Colore e forma: off-white to slightly yellow powder

Peso molecolare: 258.23g/mol

Ref: 54-BIA2301

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Purezza: 95%~99%

Peso molecolare: 258.229

Ref: BP-SBP03513

Alternariol (Standard)

CAS: 641-38-3

Alternariol (Standard) is the standard substance of Alternariol, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Alternariol (AOH), a mycotoxin synthesized by Alternaria species, displays numerous therapeutic and biological effects, including phytotoxic, cytotoxic, anti-HIV, anti-cancer, and anti-microbial properties. It functions by inhibiting the catalytic activity of topoisomerase I and II enzymes.

Formula: C₁₄H₁₀O₅

Colore e forma: Solid

Peso molecolare: 258.23

Ref: TM-TMSM-0403

Alternariol

CAS: 641-38-3

Alternariol, a natural product from Etoac, demonstrates anti-inflammatory activity and modulates TLR signaling and apoptotic proteins while being inactive against methyltransferases.

Formula: C₁₄H₁₀O₅

Purezza: 99.57%

Colore e forma: Solid

Peso molecolare: 258.23

Ref: TM-T14196

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Purezza: ≥ 98.0%

Colore e forma: White to brown solid

Peso molecolare: 258.23

Ref: 7W-GW2387

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Peso molecolare: 258.23

Ref: 4Z-A-252001

Alternariol-d4

CAS: 641-38-3

Formula: C₁₄H₆D₄O₅

Colore e forma: White To Off-White Solid

Peso molecolare: 262.25

Ref: 4Z-A-252002

Alternariol

CAS: 641-38-3

Alternariol is a natural product that is extracted from the plant Etoac. It has been shown to have anti-inflammatory properties in vitro and in vivo in murine hepatoma cells, as well as in human serum. Alternariol also has an effect on toll-like receptor signaling and pro-apoptotic protein expression. Alternariol was found to be inactive against methyl transferase enzymes, which can lead to its enzymatic inactivation. The LC-MS/MS method for the detection of alternariol was developed using a surface methodology.

Formula: C₁₄H₁₀O₅

Purezza: Min. 95%

Colore e forma: Off-White To Beige To Light Brown Solid

Peso molecolare: 258.23 g/mol

Ref: 3D-FA17330

Alternariol

CAS: 641-38-3

Formula: C₁₄H₁₀O₅

Peso molecolare: 258.23

Ref: ST-EA-CP-A297000

Alternariol

CAS: 641-38-3

Stability Hygroscopic
Applications Alternariol is an alternaria mycotoxin and genotoxin, found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Asam S et al. J Agric Food Chem. 2009 Jun 24;57(12):5152-60.Fehr M et al. Mol Nutr Food Res. 2009 Apr;53(4):441-51Vejdovszky K. et al. Toxicol Lett. 2017 Feb 5;267:45-52.

Formula: C₁₄H₁₀O₅

Colore e forma: Light Brown

Peso molecolare: 258.23

Ref: TR-A575760

Alternariol-d2

Prodotto controllato

CAS: 641-38-3

Applications Alternariol-d2 is labelled version of Alternariol (A575760), an alternaria mycotoxin and genotoxin found in common edible crops. It inhibits the activity of various DNA-topoisomerases, increasing the rate of DNA strand breaks.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Asam, S., et al.: J. Agric. Food Chem., 57, 5152 (2009); Fehr, M., et al.: Mol. Nut. Food Res., 53, 441 (2009); Tiemann, U., et al.: Toxicol. Lett., 186, 139 (2009)

Formula: C₁₄H₈D₂O₅

Colore e forma: Off-White To Dark Brown

Peso molecolare: 260.24

Ref: TR-A575762