CAS 6456-44-6

Pyridinium, 3-(aminocarbonil)-1-metil-, ioduro (1:1)

Descrizione:

Pyridinium, 3-(aminocarbonil)-1-metil-, ioduro (1:1), comunemente noto come un sale di piridinio, è un composto di ammonio quaternario caratterizzato dalla sua struttura ad anello di piridina sostituita con un gruppo aminocarbonile e un gruppo metile. Questo composto presenta tipicamente un aspetto cristallino bianco a bianco sporco ed è solubile in solventi polari come acqua e alcoli a causa della sua natura ionica. La presenza dell'ione ioduro contribuisce alla sua solubilità e può influenzare la sua reattività e stabilità. I sali di piridinio sono noti per la loro capacità di agire come forti elettrofili, rendendoli utili in varie reazioni di sintesi organica. Inoltre, il gruppo aminocarbonile può partecipare a legami idrogeno, migliorando le interazioni del composto con altre molecole. Le proprietà del composto, inclusi il punto di fusione, il punto di ebollizione e la reattività, possono variare in base alle condizioni ambientali e alla presenza di altre specie chimiche. In generale, questa sostanza è di interesse sia nella chimica organica sintetica che in potenziali applicazioni in farmacologia.

Formula: C₇H₉N₂O·I

InChI: InChI=1S/C7H8N2O.HI/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H

InChI key: InChIKey=IWEIZMCTGMHCRE-UHFFFAOYSA-N

SMILES: C(N)(=O)C1=C[N+](C)=CC=C1.[I-]

Sinonimi:

• 3-(Aminocarbonyl)-1-methylpyridinium iodide
• 3-Carbamoyl-1-Methylpyridinium
• 3-Carbamoyl-1-methylpyridinium iodide
• N'-{3-[(2,3-dihydro-1H-inden-5-yloxy)methyl]benzoyl}-2,6-dimethoxybenzohydrazide
• Nicotinamide methiodide
• Nsc 23359
• Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide
• Pyridinium, 3-(aminocarbonyl)-1-methyl-, iodide (1:1)
• Pyridinium, 3-carbamoyl-1-methyl-, iodide
• Pyridinium, 3-carbamoyl-1-methyl-, iodide (8CI)
• Pyridinium, 3-carbamyl-1-methyl-, iodide
• 1-Methylnicotinamide iodide
• 3-(aminocarbonyl)-1-methylpyridiniumiodide
• 1-methylpyridine-5-carboxamide iodide
• 1-Methyl-3-carbamoylpyridinium·iodide
• nicotinamidemethiodide
• N-METHYLNICOTINAMIDE IODIDE
• 1-METHYLNICOTINAMIDE IODIDE SALT
• 1-METHYL-NICOTINAMIDE IODIDE
• 3-carbamoyl-1-methylpyridiniumiodide
• 3-(aminocarbonyl)-1-methyl-pyridiniuiodide
• LABOTEST-BB LT00233117
• N-METHYLNICOTINIC ACID AMIDE IODIDE SALT

4-Iodo-1-methyl-1,2-dihydropyridine-3-carboxamide

CAS: 6456-44-6

Formula: C₇H₉IN₂O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 264.0636

Ref: IN-DA003EIR

1-Methylnicotinamide-13C-d3 Iodide

CAS: 6456-44-6

Formula: C₆₁₃CH₆D₃N₂O·I

Colore e forma: Pale Yellow Solid

Peso molecolare: 141.17 126.91

Ref: 4Z-N-133004

3-Carbamoyl-1-methylpyridin-1-ium iodide

CAS: 6456-44-6

3-Carbamoyl-1-methylpyridin-1-ium iodide

Purezza: 98%

Peso molecolare: 264.06g/mol

Ref: 54-OR92560

1-Methylnicotinamide Iodide

CAS: 6456-44-6

Formula: C₇H₉N₂O·I

Colore e forma: Pale Yellow Solid

Peso molecolare: 137.16 126.91

Ref: 4Z-N-133003

1-Methylnicotinamide Iodide

Prodotto controllato

CAS: 6456-44-6

Formula: C₇H₉N₂O·I

Colore e forma: Neat

Peso molecolare: 264.06

Ref: 86-MM0552.05

1-Methyl-nicotinamide Iodide

Prodotto controllato

CAS: 6456-44-6

Applications A nicotinic acid derivative which shows a dopaminergic neurotoxicity.
References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),

Formula: C₇H₉IN₂O

Colore e forma: Neat

Peso molecolare: 264.06

Ref: TR-M323235

1-Methylnicotinamide-d3 Iodide

Prodotto controllato

CAS: 6456-44-6

Applications 3-(Aminocarbonyl)-1-methylpyridinium-d3 Iodide is the isotope labelled derivative of 1-Methylnicotinamide (M323235), a nicotinic acid derivative which shows a dopaminergic neurotoxicity.
References Rollema, H., et al.: J. Med. Chem., 33, 2221 (1990),

Formula: C₇H₆D₃IN₂O

Colore e forma: Light Yellow

Peso molecolare: 267.08

Ref: TR-M323237

3-Carbamoyl-1-methylpyridin-1-ium iodide

CAS: 6456-44-6

Purezza: 98%

Peso molecolare: 264.0660095

Ref: 10-F791031

1-Methyl-nicotinamide iodide

CAS: 6456-44-6

1-Methyl-nicotinamide iodide is a drug that has been used in clinical trials for the treatment of type 2 diabetes mellitus. It is thought to work by increasing the sensitivity of cells to insulin, which may be related to its ability to bind to protein amide groups and form hydrogen bonds with the amino acid side chains. The compound also has been shown to increase the activity of the enzyme glycogen synthase in rats. 1-Methyl-nicotinamide iodide is soluble in water and human serum, and shows low solubility in ethanol. It has not been studied in humans, but animal studies have shown that it can be absorbed orally and metabolized into hippuric acid, which is excreted as a metabolic product through urine. Animal studies also showed that 1-methyl-nicotinamide iodide inhibits glucose production by pancreatic beta cells, which may lead to an increased insulin response after eating.

Formula: C₇H₉IN₂O

Purezza: Min. 95%

Colore e forma: Off-White Powder

Peso molecolare: 264.06 g/mol

Ref: 3D-FM25888

3-Carbamoyl-1-methylpyridin-1-ium iodide monohydrate

CAS: 6456-44-6

Formula: C₇H₉IN₂O

Purezza: 96%

Peso molecolare: 264.066

Ref: 10-F181849

1-Methylnicotinamide Iodide

CAS: 6456-44-6

Colore e forma: Neat

Ref: 61-FOR0552.05