CAS 64987-85-5

Succinimidil 4-(N-maleimidometil) cicloesanocarboxilato

Descrizione:

Succinimidil 4-(N-maleimidometil) cicloesanocarboxilato, con il numero CAS 64987-85-5, è un composto chimico comunemente utilizzato in applicazioni di bioconjugazione e etichettatura delle proteine. Presenta un gruppo funzionale di estere succinimidile, noto per la sua capacità di reagire con gruppi amminici sulle proteine, facilitando la formazione di legami ammidici stabili. La presenza di un gruppo maleimide consente la coniugazione selettiva a gruppi tiol, rendendolo particolarmente utile nella creazione di bioconjugati mirati. Questo composto è tipicamente caratterizzato dal suo stato solido a temperatura ambiente ed è solubile in solventi organici come il dimetilsolfossido (DMSO) e il dimetilformammide (DMF). La sua reattività e specificità lo rendono prezioso in vari campi, inclusi biochimica e biologia molecolare, per applicazioni come la somministrazione di farmaci, saggi diagnostici e lo sviluppo di agenti terapeutici. Le condizioni di manipolazione e stoccaggio adeguate sono essenziali per mantenere la sua stabilità e reattività, poiché potrebbe essere sensibile all'umidità e alla luce.

Formula: C₁₆H₁₈N₂O₆

InChI: InChI=1S/C16H18N2O6/c19-12-5-6-13(20)17(12)9-10-1-3-11(4-2-10)16(23)24-18-14(21)7-8-15(18)22/h5-6,10-11H,1-4,7-9H2

InChI key: InChIKey=JJAHTWIKCUJRDK-UHFFFAOYSA-N

SMILES: C(N1C(=O)C=CC1=O)C2CCC(C(ON3C(=O)CCC3=O)=O)CC2

Sinonimi:

• (2,5-Dioxopyrrolidin-1-yl) 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carboxylate
• 1-[(4-{[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl}cyclohexyl)methyl]-1H-pyrrole-2,5-dione
• 1H-Pyrrole-2,5-dione, 1-[[4-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]cyclohexyl]methyl]-
• 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexancarboxylate
• 2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate
• 4-(N-Maleimidomethyl)cyclohexane-1-carboxylic acid N-hydroxysuccinimide ester
• 4-(N-Maleimidomethyl)cyclohexanecarboxylic acid N-hydroxysuccinimide ester
• Cyclohexanecarboxylic acid, 4-[(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)methyl]-, 2,5-dioxo-1-pyrrolidinyl ester
• N-Hydroxysuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
• N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate
• N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate
• N-Succinimidyl 4-(maleimidomethyl)cyclohexanecarboxylate
• N-Succinimidyl4-(N-maleimidomethyl)cyclohexane-1-carboxylate
• NSC 344483
• Smcc
• Succinimidyl 4-(N-maleimidomethyl)cyclohexanecarboxylate
• Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate
• Succinimidyl 4-[maleimidomethyl]cyclohexan-1-carboxylate

N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

Formula: C₁₆H₁₈N₂O₆

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 334.3239

Ref: IN-DA0038KF

SMCC

CAS: 64987-85-5

SMCC

Purezza: ≥98%

Peso molecolare: 334.32g/mol

Ref: 54-BUP16020

N-Succinimidyl 4-(N-Maleimidomethyl)cyclohexanecarboxylate

CAS: 64987-85-5

Formula: C₁₆H₁₈N₂O₆

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 334.33

Ref: 3B-S0853

Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

Succinimidyl-4-(N-maleimidomethyl)cyclohexane-1-carboxylate

Formula: C₁₆H₁₈N₂O₆

Purezza: By hplc: 99.8% (Typical Value in Batch COA)

Colore e forma: white solid

Peso molecolare: 334.32g/mol

Ref: 54-BICL206

SMCC

CAS: 64987-85-5

SMCC (N-Succinimidyl 4-(N-maleimidomethyl)cycl) is a heterobifunctional protein crosslinker.

Formula: C₁₆H₁₈N₂O₆

Purezza: 98.96% - 99.53%

Colore e forma: White Crystalline Solid

Peso molecolare: 334.32

Ref: TM-T9116

N-Succinimidyl 4-(Maleimidomethyl)cyclohexane-1-carboxylate

Prodotto controllato

CAS: 64987-85-5

Applications A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. It conjugates anti-digoxin F(ab’)2 fragments to ß-galactosidase. Conjugates hIgG to alkaline phosphatase.Spacer Arm: 11.6 Angstroms
References Maham, D.G., et al.: Anal. Biochem., 162, 163 (1987), Yoshitake, S., et al.: Eur. J. Biochem., 101, 395 (1979), Freytag, J.W., et al.: Clin. Chem., 30(9), 1494 (1984), Mahan, D.E., et al.: Anal. Biochem., 162, 163 (1987), Peeters, J.M., et al.: J. Immunol. Meth., 120, 133 (1989),

Formula: C₁₆H₁₈N₂O₆

Colore e forma: Neat

Peso molecolare: 334.32

Ref: TR-S690400

N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate

CAS: 64987-85-5

N-Succinimidyl 4-(maleimidomethyl)cyclohexane-1-carboxylate is a versatile compound with a wide range of applications. It is commonly used in research settings as a cross-linking agent and can be utilized in the synthesis of various compounds such as ribavirin, farnesene, temozolomide, gliclazide, and more.

Formula: C₁₆H₁₈N₂O₆

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 334.32 g/mol

Ref: 3D-FS27894

2,5-Dioxopyrrolidin-1-yl 4-((2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl)cyclohexanecarboxylate

CAS: 64987-85-5

Formula: C₁₆H₁₈N₂O₆

Purezza: 95%

Colore e forma: Solid, White powder

Peso molecolare: 334.328

Ref: 10-F214622

Succinimidyl-4-(N- (N-maleimidomethyl) cyclohexane-1-carboxylate (SMCC), 98%

CAS: 64987-85-5

Formula: C₁₆H₁₈N₂O₆

Purezza: min. 98%

Colore e forma: White, Crystalline powder

Peso molecolare: 334.32

Ref: SR-24088