CAS 65-31-6

Idrogeno di nicotina (-)-tartrato (+)

Descrizione:

Idrogeno di nicotina (-)-tartrato (+), con il numero CAS 65-31-6, è un sale formato dall'alcaloide nicotina e dall'acido tartarico. Questo composto è caratterizzato dalla sua natura chirale, poiché contiene sia la (-)-nicotina, che è l'enantiomero che si verifica naturalmente, sia l'ione (+)-tartrato. Appare tipicamente come un solido cristallino bianco ed è solubile in acqua, una proprietà comune a molti sali. Il composto mostra attività farmacologica, principalmente a causa della presenza di nicotina, che agisce come uno stimolante che influisce sul sistema nervoso centrale. Le sue applicazioni si trovano spesso in contesti di ricerca, in particolare in studi relativi agli effetti della nicotina sulla neurotrasmissione e sulla dipendenza. Inoltre, la presenza del gruppo tartrato può influenzare la stabilità e la solubilità del composto, rendendolo rilevante nella formulazione di prodotti farmaceutici. In generale, Idrogeno di nicotina (-)-tartrato (+) funge da composto importante sia nella ricerca chimica che nelle potenziali applicazioni terapeutiche.

Formula: C₁₈H₂₆N₂O₁₂

InChI: InChI=1/C10H14N2.C4H6O6/c1-12-7-3-5-10(12)9-4-2-6-11-8-9;5-1(3(7)8)2(6)4(9)10/h2,4,6,8,10H,3,5,7H2,1H3;1-2,5-6H,(H,7,8)(H,9,10)/t10-;/m0./s1

InChI key: InChIKey=QLDPCHZQQIASHX-LDGFUSNJSA-N

SMILES: [C@@H]([C@H](C(O)=O)O)(C(O)=O)O.CN1[C@@H](CCC1)C=2C=CC=NC2

Sinonimi:

• (-)-Nicotine ditartrate
• (-)-Nicotine hydrogen (+)-tartrate
• 3-(1-Methylpyrrolidin-2-Yl)Pyridine 2,3-Dihydroxybutanedioate (1:1)
• 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine 2,3-dihydroxybutanedioate (salt)
• 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine bis(2,3-dihydroxybutanedioate) (salt)
• NSC 97238
• Nicotine acid tartrate
• Nicotine bitartrate
• Nicotine tartrate
• Nicotine, tartrate (1:2)
• Np002
• Pyridine, 3-(1-methyl-2-pyrrolidinyl)-, (S)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (1:2)
• Pyridine, 3-[(2S)-1-methyl-2-pyrrolidinyl]-, (2R,3R)-2,3-dihydroxybutanedioate (1:2)
• S-(-)-Nicotine hydrogen-(+)-tartrate
• pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutanedi
• nicotinehydrogentartrate
• tartratedenicotine
• (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE TARTRATE SALT
• (-)-NICOTINE TARTRATE SALT
• (-)-1-METHYL-2-[3-PYRIDYL]PYRROLIDINE DI-(+) TARTRATE SALT
• nicotineacidtartrate
• pyridine,3-(1-methyl-2-pyrrolidinyl)-,(s)-,(r-(r*,r*))-2,3-dihydroxybutane
• NICOTINE HYDROGEN-L-TARTRATE
• (-)-NICOTINE HYDROGEN TARTRATE SALT
• (-)-nicotinehydrogentartrate
• nikotinbitartrat
• (S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE TARTRATE SALT
• (S)-3-(1-METHYL-2-PYRROLIDINYL)PYRIDINE, DI-D-TARTRATE
• (S)-3-(1-METHYL-2-PYRROLINDINYL)PYRIDINE, DI-D-TARTRATE

Nicotine Bi-L-(+)-tartrate Dihydrate

CAS: 2624-48-8, 6019-06-3, 65-31-6

Formula: C₁₀H₁₄N₂·2C₄H₆O₆·2H₂O

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 498.44

Ref: 3B-N0080

NICOTINE DITARTRATE CRS

CAS: 65-31-6

NICOTINE DITARTRATE CRS

Formula: C₁₈H₂₆N₂O₁₂

Peso molecolare: 462.4052

Ref: 41-N0590200

(-)-Nicotine hydrogen tartrate salt

CAS: 65-31-6

Formula: C₁₀H₁₄N₂·2C₄H₆O₆(anhydrous)

Purezza: (HPLC) 98.5 - 101.5 % (anhydrous basis)

Colore e forma: White to almost white powder

Peso molecolare: 462.41 (anhydrous)

Ref: 7W-GL9693

Nicotine ditartrate

Prodotto controllato

CAS: 65-31-6

Formula: C₁₀H₁₄N₂C₄H₆O₆

Colore e forma: Neat

Peso molecolare: 462.41

Ref: 04-C15520200

(-)-Nicotine Ditartrate

CAS: 65-31-6

Formula: C₁₀H₁₄N₂C₄H₆O₆

Peso molecolare: 162.24 2*150.09

Ref: 4Z-N-0690

Nicotine ditartrate

CAS: 65-31-6

Natural alkaloid

Formula: C₁₀H₁₄N₂C₄H₆O₆

Purezza: ≥ 95.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 462.41

Ref: 5G-80224

(-)-Nicotine Ditartrate

CAS: 65-31-6

Applications (-)-Nicotine ditartrate is a potent agonist of AChR.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Rodriguez, J. et al.: Psychopharmacol., 231, 4455 (2014);

Formula: C₁₀H₁₄N₂·2C₄H₆O₆

Colore e forma: Off-White

Peso molecolare: 462.41

Ref: TR-N424598

(-)-Nicotine ditartrate

CAS: 65-31-6

(-)-Nicotine ditartrate is a polymorphic form of nicotine. It is a hydrogen tartrate salt with the chemical formula C10H14N2O4·H2O. (-)-Nicotine ditartrate has been shown to improve locomotor activity and reduce cortisol concentration in mice. In addition, this compound has been shown to inhibit oxidative injury in mice by reducing reactive oxygen species production. (-)-Nicotine ditartrate is also able to inhibit glutamate release from nerve terminals, which may be due to its ability to stimulate nicotinic acetylcholine receptors (nAChRs). Further, it can induce apoptosis in cancer cells through activation of the MCL-1 protein and inhibition of cholinergic neurotransmission. This drug can also be used as an electrochemical impedance spectroscopy probe for the detection of reactive oxygen species.

Formula: C₁₀H₁₄N₂·2C₄H₆O₆

Purezza: Min. 95%

Peso molecolare: 462.41 g/mol

Ref: 3D-AAA06531