CAS 65-49-6

Acido 4-aminosalicilico

Descrizione:

Acido 4-aminosalicilico, noto anche come acido para-aminosalicilico (PAS), è un composto aromatico con la formula molecolare C7H9NO3. Presenta sia un gruppo amminico (-NH2) che un gruppo acido carbossilico (-COOH) attaccati a una struttura di acido salicilico, rendendolo un membro della famiglia dei salicilati. Questo composto appare come una polvere cristallina bianca o bianco sporco ed è solubile in acqua, il che ne migliora la biodisponibilità. Acido 4-aminosalicilico è principalmente conosciuto per il suo utilizzo come agente antitubercolare, in particolare nel trattamento della tubercolosi, specialmente nei casi resistenti ad altri farmaci. Il suo meccanismo d'azione implica l'inibizione della sintesi dell'acido folico nei batteri, ostacolando così la loro crescita. Inoltre, è stato studiato per le sue potenziali proprietà antiossidanti. Sebbene generalmente ben tollerato, può causare effetti collaterali come disturbi gastrointestinali e reazioni di ipersensibilità. Come per qualsiasi composto farmaceutico, una corretta gestione e dosaggio sono cruciali per garantire sicurezza ed efficacia nelle applicazioni terapeutiche.

Formula: C₇H₇NO₃

InChI: InChI=1/C7H7NO3/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,9H,8H2,(H,10,11)

InChI key: InChIKey=WUBBRNOQWQTFEX-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(O)C=C(N)C=C1

Sinonimi:

• 2-Hydroxy-4-aminobenzoic acid
• 3-Hydroxy-4-carboxyaniline
• 4-Amino-2-hydroxybenzoic acid
• 4-Aminosalicylsaure
• 4-Asa
• 4-Carboxy-3-hydroxyaniline
• Acide 4-aminosalicylique
• Acido 4-Aminosalicilico
• Amino-PAS
• Aminosalicylic Acid
• Apacil
• Apas
• Benzoic acid, 4-amino-2-hydroxy-
• Deapasil
• Entepas
• Euteropas
• Gabbropas
• Granupas
• Monopass
• Nsc 2083
• Nsc 211698
• Osacyl
• PAS
• PAS (acid)
• Pamacyl
• Pamisyl
• Para-Pas
• Para-aminosalicylic acid
• Paramycin
• Parasal
• Parasalicil
• Parasalindon
• Pasa
• Pasalon
• Pasara
• Pasem
• Paser
• Pask
• Pasmed
• Pasnodia
• Pasolac
• Propasa
• Rezipas
• Salicylic acid, 4-amino-
• Sanipirol-4
• p-Aminosalicylic acid
• SCHIFF REAGENT
• SCHIFF REAGENT, HOTCHKISS/MCMANUS
• SCHIFF'S REAGENT FOR ALDEHYDES
• SCHIFFS REAGENT
• SCHIFF'S REAGENT
• PERIODIC ACID-SCHIFF
• FUCHSIN SULFUROUS ACID
• 4-amino-2-hydroxy-benzoicaci
• SCHIFF REAGENT SOLUTION, MODIFIED
• 4-Amino-2-hydroxbenzoicacid
• 4-Aminosalicyclic acid
• 4-AMINOSALICYLIC ACID
• SCHIFF'S FUCHSIN-SULFITE REAGENT

4-Aminosalicylic acid, 98+%

CAS: 65-49-6

Competitive pteridine synthetase inhibitor, has antibacterial capable of inhibiting the growth of Mycobacterium tuberculosis. It inhibits NF-B and folic acid synthesis. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and labe

Formula: C₇H₇NO₃

Purezza: 98+%

Colore e forma: White to pale brown or pale grey, Powder

Peso molecolare: 153.14

Ref: 02-B23289

Aminosalicylic Acid

CAS: 65-49-6

Aromatic amino-alcohol-phenols, aromatic amino-acid-phenols and other aromatic amino compounds with oxygen function

Formula: C₇H₇NO₃

Colore e forma: White Beige Powder

Peso molecolare: 153.04259

Ref: 45-1026401

4-Amino-2-hydroxybenzoic acid

CAS: 65-49-6

Formula: C₇H₇NO₃

Purezza: 96%

Colore e forma: Solid

Peso molecolare: 153.1354

Ref: IN-DA003KS5

4-Aminosalicylic acid

CAS: 65-49-6

4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Formula: C₇H₇NO₃

Purezza: 97.03% - 98.39%

Colore e forma: Minute Crystals From Alc Solid

Peso molecolare: 153.14

Ref: TM-T1296

4-Aminosalicylic acid

CAS: 65-49-6

4-Aminosalicylic acid

Purezza: ≥95%

Peso molecolare: 153.14g/mol

Ref: 54-BUP19585

4-Aminosalicylic acid

CAS: 65-49-6

Formula: C₇H₇NO₃

Purezza: (Titration) 98.5 - 101.5 %

Colore e forma: White to pale yellow or pale brown

Peso molecolare: 153.14

Ref: 7W-GM8827

Mesalazine (Mesalamine) EP Impurity E

CAS: 65-49-6

Formula: C₇H₇NO₃

Colore e forma: Brown Solid

Peso molecolare: 153.14

Ref: 4Z-M-1740

4-Amino-2-hydroxybenzoic acid

CAS: 65-49-6

4-Amino-2-hydroxybenzoic acid

Formula: C₇H₇NO₃

Purezza: 99%

Colore e forma: nearly white powder

Peso molecolare: 153.13538g/mol

Ref: 54-OR22063

4-Aminosalicylic acid

CAS: 65-49-6

Formula: C₇H₇NO₃

Colore e forma: Neat

Peso molecolare: 153.14

Ref: 04-C10227010

4-Aminosalicylic acid (Standard)

CAS: 65-49-6

4-Aminosalicylic acid (Standard) is the standard substance of 4-Aminosalicylic acid, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. 4-Aminosalicylic acid (para-aminosalicylic acid) is an analog of para-aminobenzoic acid (PABA) with antitubercular activity.

Formula: C₇H₇NO₃

Peso molecolare: 153.14

Ref: TM-TMSM-0270

4-Aminosalicylic Acid

CAS: 65-49-6

Formula: C₇H₇NO₃

Purezza: >98.0%(T)

Colore e forma: White to Light gray to Light orange powder to crystal

Peso molecolare: 153.14

Ref: 3B-A0420

4-Aminosalicylic Acid

CAS: 65-49-6

Impurity Mesalazine EP Impurity E
Stability Hygroscopic
Applications 4-Aminosalicylic Acid is an antibiotic used to treat tuberculosis.
References Horita, Y., et al.: Bioorg. Med. Chem. Lett., 19, 6313 (2009); Martins, M., et al.: J. Biol. Chem., 284, 18726 (2009); Fourches, D., et al.: Chem. Res. Toxicol., 23, 171 (2010);

Formula: C₇H₇NO₃

Colore e forma: Beige

Peso molecolare: 153.14

Ref: TR-A629220

Mesalazine EP Impurity E

CAS: 65-49-6

Formula: C₇H₇O₃N

Peso molecolare: 153.14

Ref: ST-EA-CP-M11005

4-Aminosalicylic acid

CAS: 65-49-6

4-Aminosalicylic acid (4-ASA) is a drug with anti-inflammatory and analgesic properties. It is used in the treatment of bowel disease, including ulcerative colitis and Crohn's disease. 4-ASA binds to the 4th carbon on the para position of p-hydroxybenzoic acid, which is a metabolite of salicylic acid. This binding inhibits the activity of proton pumps that are responsible for maintaining intracellular pH levels in cells. It also prevents the production of inflammatory prostaglandins by inhibiting cyclooxygenase 1 and 2, which are enzymes that catalyze the conversion of arachidonic acid to prostaglandin H2. 4-ASA also has an effect on bacterial infections by interfering with hydrogen bonding interactions between bacterial dna gyrase and dna topoisomerase II, preventing DNA replication. The x-ray crystal structures have demonstrated that 4-ASA

Formula: C₇H₇NO₃

Purezza: Min. 95%

Colore e forma: Off-White Powder

Peso molecolare: 153.14 g/mol

Ref: 3D-FA10792

4-Amino-2-hydroxybenzoic acid

CAS: 65-49-6

Formula: C₇H₇NO₃

Purezza: 95%

Colore e forma: Powder

Peso molecolare: 153.137

Ref: 10-F078671