CAS 66-76-2
:Dicumarolo
Descrizione:
Dicumarolo è un composto chimico che appartiene alla classe degli anticoagulanti, specificamente un derivato della cumarina. È caratterizzato dalla sua capacità di inibire la vitamina K epossido reduttasi, che è cruciale per la sintesi di alcuni fattori di coagulazione nel fegato. Questa inibizione porta a una diminuzione dei livelli di vitamina K attiva, riducendo così la coagulazione del sangue. Dicumarolo appare come una polvere cristallina bianca a gialla pallida ed è scarsamente solubile in acqua, ma più solubile in solventi organici come etanolo e acetone. La sua formula molecolare è C18H12O5 e ha un peso molecolare relativamente basso. Il composto è utilizzato principalmente nella ricerca e ha un'importanza storica come uno dei primi anticoagulanti orali. A causa delle sue proprietà anticoagulanti, Dicumarolo deve essere usato con cautela, poiché può portare a complicazioni emorragiche se non monitorato correttamente. Inoltre, è stato studiato per i suoi potenziali effetti su vari processi biologici, incluso il suo ruolo nella ricerca sul cancro e come possibile agente terapeutico.
Formula:C19H12O6
InChI:InChI=1/C19H12O6/c20-16-10-5-1-3-7-14(10)24-18(22)12(16)9-13-17(21)11-6-2-4-8-15(11)25-19(13)23/h1-8,20-21H,9H2
InChI key:InChIKey=DOBMPNYZJYQDGZ-UHFFFAOYSA-N
SMILES:OC=1C=2C(OC(=O)C1CC3=C(O)C=4C(OC3=O)=CC=CC4)=CC=CC2
Sinonimi:- 2H-1-Benzopyran-2-one, 3,3'-methylenebis[4-hydroxy-
- 3,3'-Methylenebis[4-hydroxy-1,2-benzopyrone]
- 3,3'-Methylenebis[4-hydroxycoumarin]
- 3,3′-Methylene-bis-(4-hydroxy-2H-benzopyran-2-one)
- 3,3′-Methylenebis(4-hydroxy-2H-chromen-2-one)
- 3,3′-Methylenebis[4-hydroxy-2H-1-benzopyran-2-one]
- Acadyl
- Acavyl
- Antitrombosin
- Baracoumin
- Bis(4-hydroxycoumarin-3-yl)methane
- Bis-3,3'-(4-hydroxycoumarinyl)methane
- Bishydroxycoumarin
- Coumarin, 3,3'-methylenebis[4-hydroxy-
- Cuma
- Cumid
- Di-4-hydroxy-3,3'-methylenedicoumarin
- Dicoumal
- Dicoumarin
- Dicoumarol
- Dicuman
- Dicumarine
- Dicumol
- Dufalone
- Kumoran
- Melitoxin
- Nc 034
- Nsc 17860
- Nsc 221570
- Nsc 41834
- Pb 2-9
- Temparin
- Trombosan
- 3,3'-Methylen-bis(4-hydroxy-cumarin)
- syringidin
- dicoumarol 4,4'-dihydroxy-3,3'-methylenebis(2H-chromen-2-one)
- 3,3’-methylenebis(4-hydroxy-2h-1-benzopyran-2-on
- 3,3’-methylene-bis(4-hydroxycoumarine)
- 3,3μ-Methylenebis(4-hydroxycoumarin), Dicumarol
- DICUMAROL
- Dicumarol,99%
- 4,4’-dihydroxy-3,3’-methylenebiscoumarin
- 3,3’-metilen-bis(4-idrossi-cumarina)
- BIS-HYDROXYCOUMARIN
- 3,3’-methylenebis(4-hydroxy-coumari
- Dikumarol
- 3,3’-methylene-bis(4-hydroxycoumarine)(french)
- nc034
- 3,3'-Methylenebis
- 3,3'-Metilen-bis(4-idrossi-cumarina)
- Dicumarol (200 mg)
- Dicoumarin (=dicoumarol)
- METHYLENEBISHYDROXYCOUMARIN
- Dicumaol R
- Di-(4-hydroxy-3-coumarinyl)methane
- 3,3'-Methylene-bis(4-hydroxycoumarine)
- 3,3’-methyleen-bis(4-hydroxy-cumarine)
- 4-HYDROXY-3-[(4-HYDROXY-2-OXO-CHROMEN-3-YL)METHYL]CHROMEN-2-ONE
- dwukumarol
- BISCUMAROL
- 3,3’-methylen-bis(4-hydroxy-cumarin)
- dicumaolr
- 3,3'-Methyleen-bis(4-hydroxy-cumarine)
- 3,3’-methylenebis[4-hydroxy-2h-1-benzopyran-2-on
- Vedi altri sinonimi
Ordinare per
Purezza (%)
0
100
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0
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50
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90
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95
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100
14 prodotti.
Dicoumarol
CAS:Formula:C19H12O6Purezza:>98.0%(T)(HPLC)Colore e forma:White to Almost white powder to crystalPeso molecolare:336.30Dicumarol
CAS:<p>Vitamin K reductase inhibitor possessing anticoagulant properties</p>Formula:C19H12O6Colore e forma:Powder, White to off whitePeso molecolare:336.30Dicoumarol
CAS:<p>Dicoumarol: an anticoagulant from moldy sweet-clover, depletes vitamin K, inhibits clotting enzymes.</p>Formula:C19H12O6Purezza:99.75% - 99.9%Colore e forma:White Or Creamy White Crystalline Powder SolidPeso molecolare:336.3Dicumarol-d8
CAS:Prodotto controllato<p>Applications Isotope labelled Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of coumarin (C755380).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sail, V., et al.: Chem. Biol. Drug. Design., 81, 334 (2013); Zsila, F., et al.: Molec. Pharma., 10, 1668 (2013); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);<br></p>Formula:C19D8H4O6Colore e forma:Light YellowPeso molecolare:344.34Dicoumarol
CAS:<p>Dicumarol is a coumarin derivative that inhibits the activity of polymerase chain reaction (PCR) by binding to DNA. It is also an inhibitor of nitrate reductase, which is an enzyme that catalyzes the conversion of nitrate to nitrite. Dicumarol binds to the response element on DNA and blocks the transcription of genes. This drug also has been shown to inhibit squamous cell carcinoma cells through interaction with DNA and protein thiols.</p>Formula:C19H12O6Purezza:Min. 95%Peso molecolare:336.30 g/mol4-hydroxy-3-[(4-hydroxy-2-oxo-2H-chromen-3-yl)methyl]-2H-chromen-2-one
CAS:Formula:C19H12O6Purezza:98.0%Colore e forma:SolidPeso molecolare:336.299Dicumarol
CAS:Prodotto controllato<p>Applications Dicumarol is a natural chemical used as an anticoagulant agents that functions as a vitamin K antagonist and is also a derivative of Coumarin (C755380).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sail, V., et al.: Chem. Biol. Drug. Design., 81, 334 (2013); Zsila, F., et al.: Molec. Pharma., 10, 1668 (2013); Brunhofer, G., et al.: Bioorg. Med. Chem., 20, 6669 (2012);<br></p>Formula:C19H12O6Colore e forma:NeatPeso molecolare:336.303,3'-Methylenebis(4-hydroxy-2H-chromen-2-one)
CAS:Formula:C19H12O6Colore e forma:SolidPeso molecolare:336.2950
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