CAS 66-86-4

Neomicina C

Descrizione:

Neomicina C, con il numero CAS 66-86-4, è un antibiotico aminoglicosidico che deriva principalmente dal batterio Streptomyces fradiae. È noto per la sua attività antibatterica ad ampio spettro, in particolare contro i batteri Gram-negativi, ed è spesso utilizzato in formulazioni topiche per trattare le infezioni. Neomicina C è caratterizzato dalla sua struttura complessa, che include più zuccheri amino legati da legami glicosidici, contribuendo al suo meccanismo d'azione che inibisce la sintesi proteica batterica. Questo composto viene tipicamente somministrato topicamente o tramite iniezione, poiché è scarsamente assorbito dal tratto gastrointestinale. Neomicina C può causare effetti collaterali, tra cui nefrotossicità e ototossicità, in particolare con uso sistemico. La sua solubilità in acqua lo rende adatto per varie applicazioni farmaceutiche, ma è importante monitorare le potenziali reazioni allergiche in individui sensibili. In generale, Neomicina C rimane un antibiotico prezioso in contesti clinici, in particolare per infezioni localizzate.

Formula: C₂₃H₄₆N₆O₁₃

InChI: InChI=1/C23H46N6O13.ClH/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22;/h5-23,30-36H,1-4,24-29H2;1H/t5-,6+,7-,8-,9-,10-,11-,12+,13-,14-,15-,16-,17-,18-,19-,20-,21-,22-,23+;/m1./s1

InChI key: InChIKey=PGBHMTALBVVCIT-VZXHOKRSSA-N

SMILES: O([C@H]1[C@H](O[C@H]2[C@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](CO)O2)[C@@H](O)[C@H](N)C[C@@H]1N)[C@H]4O[C@H](CN)[C@@H](O)[C@H](O)[C@H]4N

Sinonimi:

• Neomycin C
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-
• O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-D-streptamine
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-O-β-D-ribofuranosyl-(1→5)-O-[2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy-
• Dekamycin II
• Neomycin EP Impurity
• Framycetin Impurity 3 (Framycetin EP Impurity C)
• 4-O-(2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl)-β-D-ribofuranosyl]-2-deoxy-D-streptamine
• Framycetin EP Impurity C
• Framycetin sulfate EP Impurity C
• 5-amino-2-(aminomethyl)-6-[5-[3,5-diamino-2-[3-amino-6-(aminomethyl)-4 ,5-dihydroxy-oxan-2-yl]oxy-6-hydroxy-cyclohexyl]oxy-4-hydroxy-2-(hydro xymethyl)oxolan-3-yl]oxy-oxane-3,4-diol
• Neomycin C sulfate
• D-Streptamine, O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[O-2,6-diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→3)-β-D-ribofuranosyl-(1→5)]-2-deoxy-, monohydrochloride (9CI)

Neomycin EP Impurity C (Neomycin C)

CAS: 66-86-4

Formula: C₂₃H₄₆N₆O₁₃

Colore e forma: Off-White Solid

Peso molecolare: 614.65

Ref: 4Z-N-080016

Neomycin C

CAS: 66-86-4

Neomycin C, less potent isomer of Neomycin complex, is part of a 2-DOS aminoglycoside.

Formula: C₂₃H₄₆N₆O₁₃

Colore e forma: Solid

Peso molecolare: 614.64

Ref: TM-T73953

Neomycin EP Impurity C (Neomycin C) TFA Salt

CAS: 66-86-4

Formula: C₂₃H₄₆N₆O₁₃·xC₂HF₃O₂

Colore e forma: Off-White Solid

Peso molecolare: 614.65 x*114.02

Ref: 4Z-N-080005

Neomycin C Hexaacetate

CAS: 66-86-4

Stability Hygroscopic
Applications Neomycin C Hexaacetate is an aminoglycoside antibiotic found in many topical medications. Neomycin has been used as a preventive measure for hepatic encephalopathy and hypercholesterolemia.
References Umezawa, S., et al.: Bull. Chem. Soc. Jpm., 53, 3259 (1980); The Journal of antibiotics, NO. 2. 189 (1977);

Formula: C₂₃H₄₆N₆O₁₃•6(CH₃COOH)

Colore e forma: Neat

Peso molecolare: 614.6466005

Ref: TR-N389980

Neomycin EP impurity C (Neomycin C) trifluoroacetate

CAS: 66-86-4

Neomycin EP impurity C (Neomycin C) trifluoroacetate is a reference standard, which is a meticulously characterized chemical impurity often used in pharmaceutical analysis. This compound is derived from the fermentation of *Streptomyces fradiae*, which produces a complex mixture of aminoglycoside antibiotics, including Neomycin B and Neomycin C.

Formula: C₂₃H₄₆N₆O₁₃•(C₂HF₃O₂)x

Purezza: Min. 95%

Ref: 3D-AN183301

Neomycin C hexaacetate

CAS: 66-86-4

Please enquire for more information about Neomycin C hexaacetate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₃H₄₆N₆O₁₃

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 614.6 g/mol

Ref: 3D-AAA06686

Neomycin sulfate EP Impurity C

CAS: 66-86-4

Formula: C₂₃H₄₆N₆O₁₃

Peso molecolare: 614.65

Ref: ST-EA-CP-N53003