CAS 6610-42-0

Benzyloxycarbonil-L-glutaminilglicina

Descrizione:

Benzyloxycarbonil-L-glutaminilglicina, comunemente noto come Z-Glu-Gly, è un derivato peptidico sintetico caratterizzato dalla presenza di un gruppo protettivo benzyloxycarbonile (Z) sul residuo di glutammina. Questo composto è tipicamente utilizzato nella sintesi di peptidi e nella ricerca grazie alla sua stabilità e alla capacità di proteggere il gruppo amminico durante le reazioni chimiche. La struttura consiste in una glutammina (Glu) e una glicina (Gly) collegate da un legame peptidico, rendendolo un dipeptide. Il gruppo Z migliora la solubilità e la reattività della molecola, facilitandone l'uso in varie applicazioni biochimiche. Viene spesso impiegato nella sintesi di peptidi e proteine più complesse, fungendo da blocco di costruzione nello sviluppo di farmaci e biochimici. Il composto è generalmente stabile in condizioni di laboratorio standard, ma può essere sensibile ad acidi o basi forti, il che può portare all'idrolisi del legame peptidico. Come molti derivati peptidici, è importante maneggiarlo con cura, seguendo i protocolli di sicurezza appropriati.

Formula: C₁₅H₁₉N₃O₆

InChI: InChI=1S/C15H19N3O6/c16-12(19)7-6-11(14(22)17-8-13(20)21)18-15(23)24-9-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H2,16,19)(H,17,22)(H,18,23)(H,20,21)/t11-/m0/s1

InChI key: InChIKey=SOUXAAOTONMPRY-NSHDSACASA-N

SMILES: [C@H](C(NCC(O)=O)=O)(NC(OCC1=CC=CC=C1)=O)CCC(N)=O

Sinonimi:

• 2-[[(2S)-5-Amino-5-oxo-2-(phenylmethoxycarbonylamino)pentanoyl]amino]acetic acid
• Benzyloxycarbonyl-<span class="text-smallcaps">L</span>-glutaminylglycine
• Carbobenzoxy-<span class="text-smallcaps">L</span>-glutaminylglycine
• Glycine, N-(N²-carboxy-<span class="text-smallcaps">L</span>-glutaminyl)-, N-benzyl ester
• Glycine, N-(N²-carboxy-<span class="text-smallcaps">L</span>-glutaminyl)-, N²-benzyl ester
• Glycine, N-[N²-[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminyl]-
• Glycine, N²-[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminyl-
• N-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutaminylglycine
• N²-[(Phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-glutaminylglycine
• N^α-(Benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-glutaminylglycine
• NSC 186901
• N~2~-[(benzyloxy)carbonyl]glutaminylglycine
• Z-Gln-Gly-OH
• Glycine, N-(N2-carboxy-L-glutaminyl)-, N2-benzyl ester
• Glycine, N-[N2-[(phenylmethoxy)carbonyl]-L-glutaminyl]-
• Glycine, N2-[(phenylmethoxy)carbonyl]-L-glutaminyl-
• Glycine, N-(N2-carboxy-L-glutaminyl)-, N-benzyl ester

N-Benzyloxycarbonyl-L-glutaminylglycine, 98%

CAS: 6610-42-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₅H₁₉N₃O₆

Purezza: 98%

Colore e forma: White to pale cream, Powder

Peso molecolare: 337.33

Ref: 02-H65088

Z-Gln-Gly-OH

CAS: 6610-42-0

Substrate for tissue transaminase. De Macédo et al. described a direct continuous spectrophotometric assay for transglutaminase (TGase) activity.

Formula: C₁₅H₁₉N₃O₆

Purezza: > 99%

Colore e forma: White Powder

Peso molecolare: 337.33

Ref: 01-4002246

Z-GLN-GLY-OH

CAS: 6610-42-0

Formula: C₁₅H₁₉N₃O₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 337.3279

Ref: IN-DA00FAC9

Z-GLN-GLY-OH

CAS: 6610-42-0

Z-GLN-GLY-OH

Purezza: 98%

Peso molecolare: 337.33g/mol

Ref: 54-OR1015448

Z-Gln-Gly

CAS: 6610-42-0

Z-Gln-Gly is a protected dipeptide, which is commonly used as an intermediate in peptide synthesis. It is derived from the amino acids glutamine and glycine, with the N-terminal glutamine being protected by a benzyloxycarbonyl (Z or Cbz) group. This protective group is essential for preventing undesirable reactions at the amine site during peptide chain elongation.The primary mode of action for Z-Gln-Gly involves its use in solid-phase peptide synthesis, where the Z-group safeguards the amine functionality. This protection allows for selective reactions at other sites of the molecule until the final deprotection step, facilitating the sequential addition of amino acids.Z-Gln-Gly is used predominantly in research and development within biochemical and pharmaceutical laboratories. Its applications are critical in the synthesis of longer peptide chains and peptide-based drugs, where precision and control over the peptide structure are paramount for investigating biological processes and therapeutic functions.

Formula: C₁₅H₁₉N₃O₆

Purezza: Min. 95%

Peso molecolare: 337.33 g/mol

Ref: 3D-SZQ-3190

Z-Gln-Gly-OH

CAS: 6610-42-0

Z-Gln-Gly-OH is a synthetic dipeptide, which is a modified amino acid sequence commonly used in biochemical applications. It consists of a carbobenzoxy-protected glutamine and a glycine residue. This compound originates from custom organic synthesis, derived through specific chemical protocols to introduce protective groups that block reactive sites on the amino acids. This controlled modification alters the peptide's stability and solubility.The mode of action involves the protection of active sites during complex syntheses, enabling the sequential construction of peptide chains without unintended reactions. This protection is critical in solid-phase peptide synthesis methodologies where precision and specificity of reactions are paramount. The Z-group (benzyloxycarbonyl) ensures the stability of glutamine under various chemical conditions, preventing side reactions that may compromise the integrity of peptide constructs.In research, Z-Gln-Gly-OH finds applications in the design of peptide-based inhibitors, structural studies, and the synthesis of longer chain peptides that mimic biologically relevant structures. The protection strategy allows scientists to develop and manipulate peptides with high fidelity, facilitating advancements in understanding protein functions and interactions in physiological contexts.

Formula: C₁₅H₁₉N₃O₆

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 337.33 g/mol

Ref: 3D-FG111459

(S)-2-(5-Amino-2-(((benzyloxy)carbonyl)amino)-5-oxopentanamido)acetic acid

CAS: 6610-42-0

Formula: C₁₅H₁₉N₃O₆

Purezza: 98%

Peso molecolare: 337.332

Ref: 10-F222428