CAS 663212-40-6

VUANT1

CAS: 663212-40-6

VUANT1

Purezza: ≥95%

Peso molecolare: 434.53g/mol

Ref: 54-OR1032086

2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethan-1-one

CAS: 663212-40-6

Purezza: 98%

Peso molecolare: 434.5299988

Ref: 10-F603914

2-[[4-Ethyl-5-(2-furanyl)-4H-1,2,4-triazol-3-yl]thio]-1-(10H-phenothiazin-10-yl)-ethanone

Prodotto controllato

CAS: 663212-40-6

Applications 2-[[4-Ethyl-5-(2-furanyl)-4H-1,2,4-triazol-3-yl]thio]-1-(10H-phenothiazin-10-yl)-ethanone exhibits allosteric antagonism of insect odorant receptor ion channels.
References Jones, P.L., et al.: PLoS One, 7, 30304 (2012);

Formula: C₂₂H₁₈N₄O₂S₂

Colore e forma: Neat

Peso molecolare: 434.534

Ref: TR-E918290

2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethan-1-one

CAS: 663212-40-6

2-{[4-Ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-1-(10H-phenothiazin-10-yl)ethanone (AET) is a subunit of an ion channel inhibitor. It binds to insect odorant receptors and blocks the activation of the ion channel. AET also blocks the pyridine ring and inhibits heterologous expression in mammalian cells. AET has been shown to be toxic to insects as well as mammals. The toxicity of AET is due to its ability to inhibit ligand binding to co-receptors, which is required for neurotransmitter release.
AET has been shown to affect the sensitivity of an insect species towards different concentrations of phenothiazines, which are drugs commonly used in pest control.

Formula: C₂₂H₁₈N₄O₂S₂

Purezza: Min. 95%

Peso molecolare: 434.5 g/mol

Ref: 3D-NBB21240

VU0183254

CAS: 663212-40-6

VU0183254, an insect OR agonist, inhibits odor-driven OR complex activation by targeting the Orco subunit.

Formula: C₂₂H₁₈N₄O₂S₂

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 434.53

Ref: TM-T26325