CAS 66341-16-0

2-[(2-ammino-6-osso-3,6-diidro-9H-purin-9-il)metossi]etil diidrogeno fosfato

Descrizione:

2-[(2-ammino-6-osso-3,6-diidro-9H-purin-9-il)metossi]etil diidrogeno fosfato, con numero CAS 66341-16-0, è un composto chimico che presenta una struttura di base purinica, caratteristica delle nucleobasi presenti negli acidi nucleici. Questo composto contiene un gruppo metossile e un moiety di fosfato diidrogeno, indicando il suo potenziale ruolo nei processi biochimici, in particolare in relazione ai nucleotidi e agli acidi nucleici. La presenza dei gruppi amminici e oxo suggerisce che potrebbe partecipare a legami idrogeno e altre interazioni, influenzando la sua solubilità e reattività. Tipicamente, tali composti possono mostrare attività biologica, potenzialmente fungendo da intermediari nelle vie metaboliche o come substrati per reazioni enzimatiche. La sua complessità strutturale può anche implicare interazioni specifiche con macromolecole biologiche, rendendolo di interesse in chimica medicinale e biochimica. In generale, le caratteristiche di questo composto suggeriscono che potrebbe svolgere un ruolo nei processi cellulari, sebbene applicazioni specifiche dipenderebbero da ulteriori ricerche e contesto.

Formula: C₈H₁₄N₅O₇P

InChI: InChI=1/C8H11N5O3.H3O4P/c9-8-11-6-5(7(15)12-8)10-3-13(6)4-16-2-1-14;1-5(2,3)4/h3,14H,1-2,4H2,(H3,9,11,12,15);(H3,1,2,3,4)

SMILES: C(COCn1cnc2c1[nH]c(=N)nc2O)O.OP(=O)(O)O

Sinonimi:

• 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one phosphate (1:1)
• 6H-purin-6-one, 2-amino-1,9-dihydro-9-[(2-hydroxyethoxy)methyl]-, phosphate (1:1) (salt)
• Acycloguanosine monophosphate
• 2-amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one phosphate (salt)

Acyclovir monophosphate

CAS: 66341-16-0

Formula: C₈H₁₂N₅O₆P

Colore e forma: Solid

Peso molecolare: 305.1845

Ref: IN-DA006NA2

2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate

CAS: 66341-16-0

2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl dihydrogen phosphate

Purezza: ≥95%

Peso molecolare: 305.18g/mol

Ref: 54-OR9250T

Acyclovir Monophosphate

CAS: 66341-16-0

Stability Hygroscopic
Applications A nucleoside analog phosphates for topical use in the treatment of herpes virus infections. A topical treatment that seems to bypass a key mechanism responsible for resistance to Acyclovir.
References Furman, P., et al.: J. Virol., 32, 72 (1979), Darby, G., et al.: J. Gen. Virol., 48, 451 (1980),Prisbe, E., et al.: J. Med. Chem., 29, 671 (1986), Ellis, M., et al.: Antimicrob. Agents Chemother., 33, 304 (1989),

Formula: C₈H₁₂N₅O₆P

Colore e forma: Off-White

Peso molecolare: 305.18

Ref: TR-A192500

Acyclovir monophosphate

CAS: 66341-16-0

Acyclovir is a prodrug that is converted in vivo to its active form, acyclovir monophosphate. Acyclovir monophosphate inhibits DNA synthesis by human macrophages and other cells infected with viruses. Acyclovir inhibits the activity of the human enzyme, DNA polymerase. It binds reversibly to the viral DNA polymerase, preventing it from binding to the viral DNA and synthesizing new viral DNA strands. The hydroxyl group on acyclovir monophosphate reacts with the 3'-hydroxyl group on the terminal nucleotide of each dNTP, which prevents further elongation of the strand and thus blocks viral replication. Acyclovir also inhibits other enzymes that are important for cell metabolism, such as RNA polymerases and protein kinases. Acyclovir has minimal toxicity in humans and can be used as a diagnostic agent for hepatitis virus infections or as an antiviral agent for treating wild-type

Formula: C₈H₁₂N₅O₆P

Purezza: (%) Min. 95%

Colore e forma: Powder

Peso molecolare: 305.19 g/mol

Ref: 3D-FA07187

Acyclovir Monophosphate

CAS: 66341-16-0

Formula: C₈H₁₂N₅O₆P

Peso molecolare: 305.18

Ref: ST-EA-CP-A8053

Acyclovir monophosphate

CAS: 66341-16-0

Acyclovir monophosphate, a strong anti-HSV agent, inhibits viral DNA polymerase, blocking DNA synthesis and chain elongation.

Formula: C₈H₁₂N₅O₆P

Colore e forma: Solid

Peso molecolare: 305.18

Ref: TM-T60709