CAS 66575-29-9

Forskolina

Descrizione:

Forskolina è un composto naturale derivato dalla radice della pianta Coleus forskohlii, un membro della famiglia delle menta. È classificato come un diterpene labdano ed è noto per la sua struttura chimica distintiva, che include un telaio biciclico. Forskolina è riconosciuto per la sua capacità di attivare l'adenilato ciclasi, un enzima che aumenta i livelli di monofosfato di adenosina ciclico (cAMP) nelle cellule, portando a vari effetti fisiologici. Questo meccanismo ha suscitato interesse nei campi della farmacologia e della biochimica, in particolare per le sue potenziali applicazioni nella gestione del peso, nella salute cardiovascolare e nel trattamento dell'asma. Forskolina è tipicamente disponibile in varie forme, tra cui polveri ed estratti, ed è spesso commercializzato come integratore alimentare. La sua solubilità è principalmente in solventi organici e presenta un profilo di tossicità relativamente basso. Tuttavia, come con qualsiasi integratore, è essenziale consultare professionisti della salute prima dell'uso, specialmente per le persone con condizioni di salute sottostanti o quelle che assumono altri farmaci.

Formula: C₂₂H₃₄O₇

InChI: InChI=1S/C22H34O7/c1-8-19(5)11-14(25)22(27)20(6)13(24)9-10-18(3,4)16(20)15(26)17(28-12(2)23)21(22,7)29-19/h8,13,15-17,24,26-27H,1,9-11H2,2-7H3/t13-,15-,16-,17-,19-,20-,21+,22-/m0/s1

InChI key: InChIKey=OHCQJHSOBUTRHG-KGGHGJDLSA-N

SMILES: O[C@@]12[C@]3(C)[C@@]([C@H](O)[C@H](OC(C)=O)[C@@]1(C)O[C@](C=C)(C)CC2=O)(C(C)(C)CC[C@@H]3O)[H]

Sinonimi:

• (3R,4aR,5S,6S,10S,10aR,10bS)-3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(Acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one
• (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-Dodecahydro-5,6,10,10b-tetrahydroxy-3,4a,7,7,10a-pentamethyl-3-vinyl-1H-naphtho(2,1-b)pyran-1-one 5-acetate
• 1H-Naphtho(2,1-b)pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R-(3alpha,4abeta,5beta,6beta,6aalpha,10alpha,10abeta,10balpha))-
• 1H-Naphtho(2,1-b)pyran-1-one, dodecahydro-5-(acetyloxy)-3-ethenyl-3,4a,7,7,10a-pentamethyl-6,10,10b-trihydroxy-, (3R-(3-alpha,4a-beta,5-beta,6-beta,6a-alpha,10-alpha,10a-beta,10b-alpha))-
• 1H-Naphtho[2,1-b]pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-
• 1H-Naphtho[2,1-b]pyran-1-one, 5-(acetyloxy)-3-ethenyldodecahydro-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-, [3R-(3α,4aβ,5β,6β,6aα,10α,10aβ,10bα)]-
• 3-ethenyl-6,10,10b-trihydroxy-3,4a,7,7,10a-pentamethyl-1-oxododecahydro-1H-benzo[f]chromen-5-yl acetate
• 7-beta-Acetoxy-8,13-epoxy-1-alpha,6-beta,9-alpha-trihydroxylabd-14-en-11-one
• Boforsin
• Coleonol
• Colforsina
• Colforsina [Spanish]
• Colforsine
• Colforsine [French]
• Colforsinum
• Colforsinum [Latin]
• ForsLean
• Forskolin
• Hl 362
• L 75 1362B
• M 410
• Nsc 357088
• Nsc 375489

Forskolin

CAS: 66575-29-9

Formula: C₂₂H₃₄O₇

Purezza: >95.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 410.51

Ref: 3B-F0855

Forskolin, 98+%

CAS: 66575-29-9

Forskolin (coleonol), 66575-29-9, is a labdane diterpenoid isolated from the Indian Coleus plant which acts as an adenylyl cyclase activator. Learn more.

Formula: C₂₂H₃₄O₇

Purezza: 98+%

Colore e forma: Powder, White

Peso molecolare: 410.51

Ref: 02-J63292

Forskolin

CAS: 66575-29-9

Forskolin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₂H₃₄O₇

Purezza: (HPLC) ≥99%

Colore e forma: Powder

Peso molecolare: 410.51

Ref: 11-3733S

Forskolin (7β-acetoxy-8,13-epoxy-1α,6β,9α-trihydroxy-labd-14-en-11-one)

CAS: 66575-29-9

Heterocyclic compounds with oxygen hetero-atom(s) only nesoi

Formula: C₂₂H₃₄O₇

Colore e forma: White Crystalline Powder

Peso molecolare: 410.23045

Ref: 45-1283244

Forskolin

CAS: 66575-29-9

Formula: C₂₂H₃₄O₇

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 410.5012

Ref: IN-DA003QOW

Forskolin

CAS: 66575-29-9

Forskolin

Purezza: ≥98%

Peso molecolare: 410.5g/mol

Ref: 54-BUP17787

Forskolin from coleus forskohlii

CAS: 66575-29-9

Forskolin from coleus forskohlii

Formula: C₂₂H₃₄O₇

Purezza: By hplc: >98% (Typical Value in Batch COA)

Colore e forma: white powder

Peso molecolare: 410.50g/mol

Ref: 54-BIF1031

Forskolin

CAS: 66575-29-9

Formula: C₂₂H₃₄O₇

Purezza: ≥ 98.0% (anhydrous basis)

Colore e forma: White to off-white powder

Peso molecolare: 410.51

Ref: 7W-GP2059

Forskolin

CAS: 66575-29-9

Oridonin has anticancer activity, might be useful as adjunctive therapy for individuals with lymphoid malignancies, including the lethal disease adult T-cell leukemia.It inhibits tumor growth in glioma by inducing cell cycle arrest and apoptosis, inhibits BxPC-3 cell growth through cell apoptosis.

Formula: C₂₂H₃₄O₇

Purezza: 95%~99%

Peso molecolare: 410.507

Ref: BP-BP0593

Forskolin

CAS: 66575-29-9

Forskolin (Coleonol) is a natural product, an adenylate cyclase activator (EC50=0.5 μM).

Formula: C₂₂H₃₄O₇

Purezza: 98.83% - 99.96%

Colore e forma: Less Crystalline Solid Colorless Crystalline Solid

Peso molecolare: 410.50

Ref: TM-T2939

Forskolin

CAS: 66575-29-9

Formula: C₂₂H₃₄O₇

Peso molecolare: 410.51

Ref: 4Z-F-238001

Forskolin

CAS: 66575-29-9

Oxygen-heterocyclic compound

Formula: C₂₂H₃₄O₇

Purezza: ≥ 98.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 410.51

Ref: 5G-89664

Forskolin

CAS: 66575-29-9

Applications Forskolin is a diterpene isolated from Coleus forskohlii, possessing vasodilating and cardiostimulatory properties. Forskolin resensitizes cell receptors by activating the enzyme adenylyl cyclase and increasing the intracellular levels of cAMP.
References Lindner, E., et al.: Arzneim.-Forsch., 28, 284 (1984), Hoever, G., et al.: J. Med. Chem., 48, 1256 (2005), Lai, S., et al.: Eur. J. Clin. Microbiol. Infect. Dis., 24, 5831 (2005),

Formula: C₂₂H₃₄O₇

Colore e forma: Neat

Peso molecolare: 410.50

Ref: TR-F701800

Forskolin

CAS: 66575-29-9

Forskolin is a diterpene compound from Asian medicinal plant Coleus forskohlii. It is an activator of adenylate cyclase, causing increase in cellular levels of cAMP. It has anti-neuroinflammatory activity since it reduced microglial activation and astrocyte activation in the brain of rodent models for cerebral amyloidosis. Forskolin also reduced amyloid beta plaques deposition in cortex and hippocampus.

Formula: C₂₂H₃₄O₇

Purezza: Min. 97 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 410.5 g/mol

Ref: 3D-FF23593

Forskolin - Bio-X ™

CAS: 66575-29-9

Forskolin is a compound derived from the medicinal plant Coleus forskohlii. As an activator of adenylate cyclase, Forskolin causes increases cellular levels of cAMP, and can be used in cell physiology research. It also has antihypertensive, platelet aggregation inhibitory and smooth muscle relaxant effects.

Formula: C₂₂H₃₄O₇

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 410.5 g/mol

Ref: 3D-BF164487

Forskolin

CAS: 66575-29-9

Purezza: 97%

Peso molecolare: 410.51

Ref: 10-M04088