CAS 66803-19-8

Solfato di micronomicina

Descrizione:

Solfato di micronomicina è un antibiotico aminoglicosidico derivato da Micromonospora purpurea, utilizzato principalmente per le sue proprietà antibatteriche. Mostra un ampio spettro di attività contro vari batteri Gram-negativi e alcuni Gram-positivi, rendendolo efficace nel trattamento delle infezioni, in particolare quelle causate da ceppi resistenti. Il composto agisce inibendo la sintesi proteica batterica, che è cruciale per la crescita e la replicazione batterica. Solfato di micronomicina è tipicamente somministrato per iniezione ed è noto per la sua tossicità relativamente bassa rispetto ad altri aminoglicosidi, sebbene possa comunque presentare rischi come nefrotossicità e ototossicità. La forma solfato ne migliora la solubilità e stabilità in soluzione, facilitandone l'uso in contesti clinici. Come con altri aminoglicosidi, il monitoraggio attento dei livelli del farmaco nel flusso sanguigno è essenziale per evitare effetti avversi. In generale, Solfato di micronomicina è un antibiotico prezioso nell'arsenale terapeutico contro le infezioni batteriche, in particolare nei casi in cui altri trattamenti possono fallire a causa della resistenza.

Formula: C₂₀H₄₃N₅O₁₁S

InChI: InChI=1/C20H41N5O7.H2O4S/c1-20(28)8-29-19(14(27)17(20)25-3)32-16-12(23)6-11(22)15(13(16)26)31-18-10(21)5-4-9(30-18)7-24-2;1-5(2,3)4/h9-19,24-28H,4-8,21-23H2,1-3H3;(H2,1,2,3,4)/t9-,10+,11-,12+,13-,14+,15+,16-,17+,18+,19+,20-;/m0./s1

InChI key: InChIKey=MQDGQSCLOYLSEK-SCFBDNQUSA-N

SMILES: O([C@@H]1[C@@H](O)[C@H](O[C@H]2O[C@H](CNC)CC[C@H]2N)[C@@H](N)C[C@H]1N)[C@@H]3[C@H](O)[C@@H](NC)[C@@](C)(O)CO3.S(=O)(=O)(O)O

Sinonimi:

• (1R,2S,3S,4R,6S)-4,6-diamino-3-{[3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl]oxy}-2-hydroxycyclohexyl 2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranoside sulfate (1:1)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-<smallcap>D</smallcap>-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
• <span class="text-smallcaps">D</smallcap>-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-<smallcap>D</smallcap>-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-<smallcap>L</span>-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (salt)
• Micronomycin sulfate
• Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-D-erythro-hexopyranosyl-(1-4)-O-(3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranosyl-(1-6))-2-deoxy-, sulfate, D-
• Micronomicin sulfate
• D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (1:?)
• D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-α-D-erythro-hexopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-, sulfate (salt)
• yranosyl-(1-4)-o-(3-deoxy-4-c-methyl-3-(methylamino)-beta-l-arabinopyranosyl-(
• MICRONOMICIN SULFATE USP/EP/BP
• streptamine,o-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-alpha-d-erythro-hexop
• sulfate,d-1-6))-2-deoxy
• (2R,3R,4R,5R)-2-[(1S,2S,3R,4S,6R)-4,6-diamino-3-[(2R,3R,6S)-3-amino-6-(methylaminomethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol,sulfuric acid
• D-Streptamine, O-2-amino-2,3,4,6-tetradeoxy-6-(methylamino)-a-D-erythro-hexopyranosyl-(14)-O-[3-deoxy-4-C-methyl-3-(methylamino)-b-L-arabinopyranosyl-(16)]-2-deoxy-, sulfate (salt) (9CI)
• 6'-N-METHYLGENTAMICIN C1A HEMIPENTASULFATE
• Micronomicin sulfate JAS1998
• Micronomicin Sulfate CAS: 66803-19-8

Micronomicin sulfate, 590 ^mg/mg

CAS: 66803-19-8

An aminoglycoside antibiotic commonly used against Gram-negative bacteria This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU

Formula: C₂₀H₄₁N₅O₇•H₂SO₄

Colore e forma: White to off-white, Powder

Peso molecolare: 561.65

Ref: 02-J66072

(2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4,6-Diamino-3-(((2R,3R,6S)-3-amino-6-((methylamino)methyl)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol sulfate

CAS: 66803-19-8

Formula: C₂₀H₄₃N₅O₁₁S

Purezza: 95%

Colore e forma: Solid

Peso molecolare: 561.6473

Ref: IN-DA00FA9E

Micronomicin sulfate

CAS: 66803-19-8

Micronomicin sulfate

Purezza: ≥95%

Ref: 54-BUP20960

Micronomicin sulfate

CAS: 66803-19-8

Micronomicin sulfate (Gentamicin C2b sulfate) is an aminoglycoside antibiotic with antimicrobial activity that inhibits neuraminidase N1 of influenza A virus.

Formula: C₂₀H₄₁N₅O₇xH₂O₄S

Colore e forma: Solid

Peso molecolare: #VALUE!

Ref: TM-T41294

Micronomicin Sulfate (~80%)

Prodotto controllato

CAS: 66803-19-8

Applications Micronomicin Sulfate is an aminoglycoside antibiotic with neuromuscular blocking activity.
References Matsukawa, S., et al.: Tohoku J. Exp. Med., 181, 471 (1997)

Formula: C₂₀H₄₁N₅O₇·H₂O₄S

Purezza: ~80%

Colore e forma: Neat

Peso molecolare: 561.65

Ref: TR-M342900

Micronomicin Sulfate

CAS: 66803-19-8

Micronomicin sulfate is an antimicrobial agent that belongs to the group of sulfonamides. It has been used in clinical studies for the treatment of chronic bronchitis. Micronomicin sulfate inhibits bacterial growth by binding to fatty acid synthesis enzymes and inhibiting membrane function. This drug also has a broad-spectrum antimicrobial action, which includes activity against gram-positive bacteria, gram-negative bacteria, and fungi. Micronomicin sulfate is not active against mycobacteria and is used in combination with other antibiotics for the treatment of infections caused by these bacteria. Micronomicin sulfate can be administered intravenously as an injection solution or orally as a tablet or syrup. It can also be given rectally as an enema solution or suppository. A formulation for intramuscular injection is also available but this formulation should not be injected into a vein or artery.

Formula: C₂₀H₄₁N₅O₇xH₂SO₄

Purezza: Min. 590 Ug/Mg

Colore e forma: Powder

Peso molecolare: 463.57 g/mol

Ref: 3D-RCA80319