CAS 66852-54-8

Propionato di halobetasolo

Descrizione:

Propionato di halobetasolo è un corticosteroide sintetico utilizzato principalmente per le sue proprietà anti-infiammatorie e immunosoppressive, in particolare nelle applicazioni dermatologiche. È caratterizzato dalla sua alta potenza, rendendolo efficace nel trattamento di varie condizioni della pelle come psoriasi ed eczema. La sostanza è una polvere cristallina bianca a bianco sporco che è praticamente insolubile in acqua ma solubile in solventi organici. Il suo meccanismo d'azione implica l'inibizione dei mediatori infiammatori, riducendo così arrossamento, gonfiore e prurito associati a disturbi della pelle. Propionato di halobetasolo è tipicamente formulato in preparazioni topiche, comprese creme, unguenti e lozioni, ed è applicato direttamente nell'area interessata. A causa della sua potenza, è generalmente raccomandato per un uso a breve termine e sotto supervisione medica per minimizzare i potenziali effetti collaterali, come l'assottigliamento della pelle o l'assorbimento sistemico. Come con tutti i corticosteroidi, devono essere seguite le linee guida per un uso corretto per garantire sicurezza ed efficacia.

Formula: C₂₅H₃₁ClF₂O₅

InChI: InChI=1S/C25H31ClF2O5/c1-5-21(32)33-25(20(31)12-26)13(2)8-15-16-10-18(27)17-9-14(29)6-7-22(17,3)24(16,28)19(30)11-23(15,25)4/h6-7,9,13,15-16,18-19,30H,5,8,10-12H2,1-4H3/t13-,15-,16-,18-,19-,22-,23-,24-,25-/m0/s1

InChI key: InChIKey=BDSYKGHYMJNPAB-LICBFIPMSA-N

SMILES: O(C(CC)=O)[C@@]1(C(CCl)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](F)([C@@H](O)C2)[C@]4(C)C([C@@H](F)C3)=CC(=O)C=C4)[H])[H]

Sinonimi:

• (6α,11β,16β)-21-Chloro-6,9-difluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
• Bmy 30056
• Cgp 14458
• Halobetasol propionate
• Miracorten
• Ulobetasol propionate
• Ultravate
• ethyl (6alpha,11beta,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17-carboxylate
• (6alpha,8xi,10xi,13xi,14xi,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate
• 21-Chloro-6alpha,9-difluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
• (6alpha,11beta,16beta)-21-chloro-6,9-difluoro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-dien-17-yl propanoate

Halobetasol Propionate

CAS: 66852-54-8

Formula: C₂₅H₃₁ClF₂O₅

Purezza: >98.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 484.96

Ref: 3B-H1457

Halobetasol Propionate

CAS: 66852-54-8

Halogenated derivatives of adrenal cortical hormones

Formula: C₂₅H₃₁ClF₂O₅

Colore e forma: White Off-White Powder

Peso molecolare: 484.18281

Ref: 45-1302906

Halobetasol-d3 Propionate

CAS: 66852-54-8

Formula: C₂₅H₂₈D₃ClF₂O₅

Colore e forma: White To Off-White Solid

Peso molecolare: 487.98

Ref: 4Z-H-021004

Halobetasol Propionate-d5

CAS: 66852-54-8

Formula: C₂₅H₂₆D₅ClF₂O₅

Colore e forma: White To Off-White Solid

Peso molecolare: 490.00

Ref: 4Z-H-021010

Halobetasol Propionate

CAS: 66852-54-8

Halobetasol Propionate

Purezza: 99%

Peso molecolare: 484.96g/mol

Ref: 54-PC109048

Halobetasol Propionate

CAS: 66852-54-8

Formula: C₂₅H₃₁ClF₂O₅

Colore e forma: Off-White Solid

Peso molecolare: 484.96

Ref: 4Z-H-021003

Halobetasol propionate

CAS: 66852-54-8

Halobetasol propionate

Purezza: ≥98%

Peso molecolare: 484.96g/mol

Ref: 54-BUP11790

Halobetasol propionate

CAS: 66852-54-8

Formula: C₂₅H₃₁ClF₂O₅

Peso molecolare: 484.96

Ref: 7W-GP0244

Halobetasol Propionate

Prodotto controllato

CAS: 66852-54-8

Formula: C₂₅H₃₁ClF₂O₅

Colore e forma: Neat

Peso molecolare: 484.96

Ref: 86-MM3634.00

Halobetasol propionate

CAS: 66852-54-8

Halobetasol propionate (BMY-30056) is the salt of halobetasol, a synthetic corticosteroid with anti-inflammatory, antipruritic, and vasoconstrictor activities.

Formula: C₂₅H₃₁ClF₂O₅

Purezza: 99.89%

Colore e forma: Distributed As 0 05% Ointment

Peso molecolare: 484.96

Ref: TM-T6529

Halobetasol Propionate

Prodotto controllato

CAS: 66852-54-8

Applications Anti-inflammatory; a dermatologic agent commonly used to treat psoriasis
References Pearce, D., et al.: Int. J. Dermatol., 45, 370 (2006),

Formula: C₂₅H₃₁ClF₂O₅

Colore e forma: Neat

Peso molecolare: 484.96

Ref: TR-H102300

Halobetasol Propionate-d5

Prodotto controllato

CAS: 66852-54-8

Formula: C₂₅D₅H₂₆ClF₂O₅

Colore e forma: Neat

Peso molecolare: 489.991

Ref: TR-H102302

Halobetasol propionate

Prodotto controllato

CAS: 66852-54-8

Halobetasol propionate is a corticosteroid that is used to treat inflammatory skin diseases such as psoriasis and atopic dermatitis. It belongs to the group of drugs known as topical steroids, which are applied to the skin. Halobetasol propionate may also be used to treat choroidal neovascularization (CNV) or ocular hypertension in patients with age-related macular degeneration, but it is not approved for this use. The mechanism of action of halobetasol propionate is not fully understood, but it has been shown to inhibit the activity of certain proteins involved in inflammation. Halobetasol propionate has been shown to be more effective than hydrocortisone in reducing the severity and frequency of cutaneous lesions in patients with psoriasis.

Formula: C₂₅H₃₁ClF₂O₅

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 484.96 g/mol

Ref: 3D-FH23728

Halobetasol propionate-d3

Prodotto controllato

CAS: 66852-54-8

Halobetasol propionate-d3 is a biocompatible polymer that binds to the effector proteins of the inflammatory response. It is used in the treatment of inflammatory bowel disease, psoriasis, and other skin diseases. Halobetasol propionate-d3 has been shown to be effective against plaque and cutaneous lesions in patients with psoriasis. This drug also inhibits the production of proinflammatory cytokines (IL-1β, IL-6, IL-8) and chemokines (MCP-1) by monocytes. The drug has been shown to be effective against autoimmune diseases due to its ability to inhibit TNFα production from macrophages. Halobetasol propionate-d3 is compatible with blood group A, B, and AB.

Formula: C₂₅H₃₁ClF₂O₅

Purezza: Min. 95%

Peso molecolare: 484.96 g/mol

Ref: 3D-FH57683

Halobetasol Propionate

CAS: 66852-54-8

Formula: C₂₅H₃₁ClF₂O₅

Peso molecolare: 484.96

Ref: ST-EA-CP-H7001