CAS 67-30-1

Acido tetraiodotiroacetico

Descrizione:

Acido tetraiodotiroacetico, comunemente noto come Tetrac, è un derivato sintetico della tiroxina (T4) ed è caratterizzato dalla presenza di quattro atomi di iodio attaccati alla sua struttura aromatica. Questo composto è noto per il suo ruolo nell'influenzare i processi metabolici ed è stato studiato per le sue potenziali applicazioni terapeutiche, in particolare nel contesto della regolazione degli ormoni tiroidei. Acido tetraiodotiroacetico presenta un'alta lipofilia a causa del suo contenuto di iodio, che influisce sulla sua solubilità e biodisponibilità. Si trova tipicamente in forma cristallina ed è stabile in condizioni di laboratorio standard. Il composto interagisce con i recettori degli ormoni tiroidei, influenzando l'espressione genica e le vie metaboliche. Le sue proprietà farmacologiche lo hanno reso un argomento di interesse in endocrinologia e ricerca metabolica. Tuttavia, come per molti composti contenenti iodio, si consiglia cautela riguardo al suo uso, poiché un eccesso di iodio può portare a disfunzione tiroidea. In generale, Acido tetraiodotiroacetico rappresenta un composto significativo nello studio degli ormoni tiroidei e dei loro analoghi.

Formula: C₁₄H₈I₄O₄

InChI: InChI=1/C14H8I4O4/c15-8-4-7(5-9(16)13(8)21)22-14-10(17)1-6(2-11(14)18)3-12(19)20/h1-2,4-5,21H,3H2,(H,19,20)

InChI key: InChIKey=PPJYSSNKSXAVDB-UHFFFAOYSA-N

SMILES: O(C1=CC(I)=C(O)C(I)=C1)C2=C(I)C=C(CC(O)=O)C=C2I

Sinonimi:

• 3,3′,5,5′-Tetraiodothyroacetic acid
• 3,5,3′,5′-Tetraiodothyroacetic acid
• 3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneacetic acid
• 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetic acid
• 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenylacetic acid
• Acetic acid, (4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)- (8CI)
• Acetic acid, [4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-
• Acide 3,5,3',5'-tetraiodothyroacetique
• Acide 3,5,3',5'-tetraiodothyroacetique [French]
• Benzeneacetic acid, 3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)-
• Benzeneacetic acid, 4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodo-
• Tetrac
• Tetraiodothyroacetic acid
• Thyroacetic acid, 3,3',5,5'-tetraiodo-
• Thyroacetic acid, 3,3′,5,5′-tetraiodo-
• 4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodobenzeneacetic acid, Tetrac
• 3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)benzeneaceticacid
• (4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)-aceticaci
• 2-[3,5-Diiodo-4-(4-hydroxy-3,5-diiodophenoxy)phenyl]acetic acid
• 3,3’,5,5’-tetraiodo-thyroaceticaci
• tetraiodothyroaceticacid
• 3,5-diiodo-4-(4-hydroxy-3,5-diiodophenoxy)-benzeneaceticaci
• 3,5,3',5'-Tetraiodothyroacetic acid
• 3,3',5,5'-TETRAIODOTHYRO-ACETIC ACID
• 3,5-DIIODO-4-(4-HYDROXY-3,5-DIIODOPHENOXY)PHENYLACETIC ACID
• [3,5-Diiodo-4-(3,5-diiodo-4-hydroxyphenoxy)phenyl]acetic acid
• acide3,5,3’,5’-tetraiodothyroacetique

3,3',5,5'-Tetraiodothyroacetic Acid

CAS: 67-30-1

Formula: C₁₄H₈I₄O₄

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Yellow to Green powder to crystal

Peso molecolare: 747.83

Ref: 3B-T3730

Liothyronine EP Impurity D

CAS: 67-30-1

Formula: C₁₄H₈I₄O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 747.83

Ref: 4Z-T-4212

Tetrac

CAS: 67-30-1

Tetrac

Purezza: ≥98%

Peso molecolare: 747.83g/mol

Ref: 54-BUP11003

Tetrac

CAS: 67-30-1

Tetrac (Tetraiodothyroacetic acid) is a derivative of L-thyroxine (T4), a thyroxine integrin receptor antagonist.Tetrac induces antiproliferation by blocking

Formula: C₁₄H₈I₄O₄

Purezza: 99.00%

Colore e forma: Solid

Peso molecolare: 747.83

Ref: TM-T36715

[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]acetic Acid (Tetraiodothyroacetic Acid)

Prodotto controllato

CAS: 67-30-1

Formula: C₁₄H₈I₄O₄

Colore e forma: Neat

Peso molecolare: 747.83

Ref: 86-MM0626.05

Liothyronine EP Impurity D

CAS: 67-30-1

Formula: C₁₄H₈I₄O₄

Peso molecolare: 747.8

Ref: ST-EA-CP-L45004

3,5,3',5'-Tetraiodo Thyroacetic Acid

Prodotto controllato

CAS: 67-30-1

Impurity Levothyroxine EP Impurity D / T4-Acetic Acid (USP)
Applications Thyroid hormone analogue. A potent Thyroxine impurity. T4-Acetic Acid (USP).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Horst, C., et al.: Biochem. J., 261, 945 (1989), Kvetny, J., et al.: Horm. Metab. Res., 24, 322 (1992), Yamauchi, K., et al.: J. Biol. Chem., 274, 8460 (1999), Davis, P., et al.: J. Endocrinol. Invest., 25, 377 (2002),

Formula: C₁₄H₈I₄O₄

Colore e forma: Yellow

Peso molecolare: 747.83

Ref: TR-T296125

Levothyroxine EP Impurity D

CAS: 67-30-1

Formula: C₁₄H₈I₄O₄

Peso molecolare: 747.82

Ref: ST-EA-CP-L18004

Tetrac

CAS: 67-30-1

Purezza: 98%

Peso molecolare: 747.832

Ref: 10-F987812

Tetraiodothyroacetic Acid (2-(4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl)acetic acid)

CAS: 67-30-1

Carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides etc, nesoi

Formula: C₁₄H₈I₄O₄

Colore e forma: Off-White Powder

Peso molecolare: 747.66015

Ref: 45-1A11700

3,5,3',5'-Tetraiodothyroacetic acid

CAS: 67-30-1

3,5,3',5'-Tetraiodothyroacetic acid (T4) is a thyroid hormone that can be found in the blood and has been shown to have angiogenic properties. T4 has been shown to bind to integrin receptors on endothelial cells and stimulate the proliferation of these cells. This hormone also has pro-apoptotic activity, inducing programmed cell death in cancer cells. T4 is used as a model system for studying the molecular pathogenesis of thyroid cancer. T4 is also able to inhibit DNA polymerase activity, which may be responsible for its ability to inhibit tumor growth.

Formula: C₁₄H₈I₄O₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 747.83 g/mol

Ref: 3D-FT28150