CAS 68-89-3

Dipirone

Descrizione:

Dipirone, noto anche come metamizolo, è un analgesico e antipiretico non oppioide comunemente usato per il sollievo dal dolore e la riduzione della febbre. È classificato come un derivato della pirazolone ed è noto per le sue potenti proprietà analgesiche. Dipirone viene tipicamente somministrato nella sua forma di sale sodico, che ne migliora la solubilità in acqua. Il composto è caratterizzato dalla sua capacità di inibire la sintesi delle prostaglandine, riducendo così il dolore e l'infiammazione. Viene spesso utilizzato in contesti clinici per la gestione del dolore severo, in particolare quando altri analgesici sono inefficaci. Tuttavia, Dipirone è stato associato a effetti collaterali gravi, tra cui agranulocitosi, una diminuzione potenzialmente letale del conteggio dei globuli bianchi, che ha portato al suo uso ristretto in alcuni paesi. La sostanza è generalmente ben assorbita quando somministrata per via orale o endovenosa, e i suoi effetti possono essere rapidi, rendendola un'opzione preziosa in scenari di dolore acuto. Nonostante la sua efficacia, i fornitori di assistenza sanitaria devono valutare i benefici rispetto ai rischi quando considerano Dipirone per il trattamento del paziente.

Formula: C₁₃H₁₆N₃NaO₄S

InChI: InChI=1/C13H19N3O4S.Na/c1-10-12(14(2)9-21(18,19)20)13(17)16(15(10)3)11-7-5-4-6-8-11;/h4-8,10,12H,9H2,1-3H3,(H,18,19,20);/q;+1/p-1/rC13H18N3NaO4S/c1-10-12(14(2)9-22(19,20)21-17)13(18)16(15(10)3)11-7-5-4-6-8-11/h4-8,10,12H,9H2,1-3H3

InChI key: InChIKey=CEOUXRNZHGKECQ-UHFFFAOYSA-N

SMILES: O=C1N(N(C)C(C)=C1N(CS(=O)(=O)O)C)C2=CC=CC=C2.[Na]

Sinonimi:

• Algocalmin
• Algopyrin
• Amoloid HV
• Amoloid LV
• Anador
• Analgin
• Analgin DAB10
• Analgine
• Andolor
• Arpf
• Collatex A/RE
• Collatex Arm Extra
• CollatexA/RE Extra
• Conmel
• Diprofarn
• Dipyrone,hydrate
• Duckammon
• E 403
• Gifaril
• Kimica Algin NH
• Kimitsu Algin NH
• Lisador
• Manutex PC-MV
• Metamizol
• Metamizole
• Metamizole Sodium
• Metamizole sodium salt
• Metapyrin
• Methamizole sodium
• Methampyrone
• Methanesulfonic acid, (antipyrinylmethylamino)-, sodium salt
• Methanesulfonic acid, 1-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt (1:1)
• Methanesulfonic acid, [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]-, sodium salt
• Methylmelubrin
• Metilon
• Narone
• Natrium-[(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methansulfonat
• Neo-melubrine
• Noramidopyrine methanesulfonate sodium
• Noramidopyrine methanesulfonate sodium salt
• Noraminophenazone methanesulfonate sodium salt
• Noraminophenazone sodium mesylate
• Novalgetol
• Novalgin
• Novamidazophen
• Novaminophenazone
• Novaminsulfone
• Novaminsulfone sodium
• Novaminsulfonium
• Novaminsulfonum
• Noveltex
• Optalgin
• Pharmalgine
• Protamon S
• Pyralgine
• Pyretin
• Pyretin (pharmaceutical)
• Restriva
• Sodium ((2,3-Dihydro-1,5-Dimethyl-3-Oxo-2-Phenyl-1H-Pyrazol-4-Yl)Methylamino)Methanesulfonate
• Sodium (antipyrinylmethylamino)methanesulfonate
• Sodium 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonate
• Sodium [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulphonate
• Sodium metamizole
• Sodium noramidopyrine methanesulfonate
• Sodium novaminsulfonate
• Sulpin
• Sulpyrin
• Sulpyrine
• [(1,5-Dimethyl-3-Oxo-2-Phenyl-Pyrazolidin-4-Yl)-Methyl-Amino]Methylsulfonyloxy Sodium
• [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
• [(2,3-Dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic acid sodium salt
• [(2,3-dihydro-1,5-dimethyl-3-oxo-2-phenyl-1H-pyrazole-4-yl)methylamino]methanesulfonate de sodium
• [(2-fenil-2,3-dihidro-1,5-dimetil-3-oxo-1H-pirazol-4-il)metilamino]metanosulfonato de sodio
• sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate
• sodium [(1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(methyl)amino]methanesulfonate hydrate (1:1:1)
• Dipyrone
• BENZALAGEN
• (antipyrinylmethylamino)-methanesulfonicacimonosodiumsalt
• SODIUM [(1,5-DIMETHYL-3-OXO-2-PHENYL-PYRAZOL-4-YL)-METHYL-AMINO]METHANESULFONATE
• 4-methylamino-1,5-dimethyl-2-phenyl-3-pyrazolonesodiummethanesulfonate
• (antipyrinylmethylamino)methanesulfonicacidsodiumsalt
• 1-phenyl-2,3-dimethylpyrazolone-(5)-4-methylaminomethanesulfonicacidsodium
• dipyron
• LABOTEST-BB LT00771955
• (antipyrinylmethylamino)-methanesulfonicacisodiumsalt
• DIPYRONE SODIUM
• 1-phenyl-2,3-dimethyl-5-pyrazolone-4-methylaminomethanesulfonatesodium
• METAMIZOL SODIUM
• SODIUM DIPYRONE

Metamizole Sodium Salt

CAS: 68-89-3

Formula: C₁₃H₁₆N₃NaO₄S

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 333.34

Ref: 3B-M3060

Dipyrone

CAS: 68-89-3

Formula: C₁₃H₁₇N₃NaO₄S

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 334.3465

Ref: IN-DA006FYJ

Metamizole sodium

CAS: 68-89-3

Metamizole sodium (Analgin) is a drug that has analgesic, anti-inflammatory, and antipyretic properties. It is the sodium sulfonate of AMINOPYRINE.

Formula: C₁₃H₁₆N₃NaO₄S

Purezza: 99.52%

Colore e forma: White Or Almost White Crystal Powder

Peso molecolare: 333.34

Ref: TM-T1191L

Metamizole Sodium Salt (Dipyrone)

CAS: 68-89-3

Formula: C₁₃H₁₆N₃O₄S·Na

Colore e forma: White To Off-White Solid

Peso molecolare: 310.35 22.99

Ref: 4Z-M-531

Dipyrone

CAS: 68-89-3

Dipyrone

Purezza: 98%

Peso molecolare: 333.34g/mol

Ref: 54-OR1029314

Metamizole sodium

CAS: 68-89-3

Metamizole sodium

Purezza: ≥98%

Peso molecolare: 333.34g/mol

Ref: 54-BUP10835

Metamizol sodium

Prodotto controllato

CAS: 68-89-3

Formula: C₁₃H₁₆N₃O₄S·Na

Colore e forma: Neat

Peso molecolare: 333.34

Ref: 04-C14942000

Dipyrone

Prodotto controllato

CAS: 68-89-3

Applications Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models. Neuroprotective & Neuroresearch Product.
References Reith, J., et al.: Lancet, 347, 422 (1996), Grau, A., et al.: J. Neurol. Sci., 171, 115 (1999), Schwarz, S., et al.: Neurology, 2000, 54, 354 (2000), Greer, D., et al.: Stroke, 39, 3029 (2008),

Formula: C₁₃H₁₆N₃O₄S·Na

Colore e forma: White

Peso molecolare: 333.34

Ref: TR-D492860

Dipyrone-d3

Prodotto controllato

CAS: 68-89-3

Stability Hygroscopic
Applications Labelled Dipyrone. Dipyrone is a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. Dipyrone is a relatively selective inhibitor of cyclooxygenase-3 (COX-3), with lower activity against COX-1 and no activity against COX-2. Dipyrone blocks PGE2-induced hyperalgesia in several models.
References Reith, J. et al.: Lancet, 347, 422 (1996); Grau, A. et al.: J. Neurol. Sci., 171, 115 (1999); Schwarz, S. et al.: Neurology, 2000, 54, 354 (2000); Greer, D. et al.: Stroke, 39, 3029 (2008);

Formula: C₁₃H₁₃D₃N₃NaO₄S

Colore e forma: Off-White

Peso molecolare: 336.36

Ref: TR-D492862

Dipyrone

CAS: 68-89-3

Dipyrone is an anti-inflammatory and analgesic drug that belongs to the group of non-steroidal anti-inflammatory drugs. It has been shown to inhibit the production of prostaglandins, which are involved in inflammation, by inhibiting cyclooxygenase. The polymerase chain reaction (PCR) method is a biochemical technique used to amplify a segment of DNA, typically for use as a genetic marker or for cloning a particular gene. A PCR assay can be used to detect the presence of bacterial DNA in a sample. Dipyrone has been shown to possess chemiluminescence activity, which is indicative of its ability to bind with DNA. This binding inhibits transcription and replication and may be responsible for the toxic effects on epidermal cells observed in animal studies. Dipyrone also has been shown to have anti-inflammatory activities through its inhibition of cyclooxygenase and its ability to inhibit neutrophil migration and function.

Formula: C₁₃H₁₆N₃NaO₄S

Purezza: Min. 95%

Colore e forma: White Solid

Peso molecolare: 333.34 g/mol

Ref: 3D-FD22539

Dipyrone Sodium Salt

CAS: 68-89-3

Formula: C₁₃H₁₆N₃O₄SNa

Peso molecolare: 310.3 : 23.0

Ref: ST-EA-CP-A231001