CAS 681260-70-8

Astressin2B trifluoroacetate salt

CAS: 681260-70-8

Formula: C₁₈₃H₃₀₇N₄₉O₅₃·xC₂HF₃O₂

Peso molecolare: 4041.69 (free base

Ref: 7W-GL0189

Astressin 2B

CAS: 681260-70-8

CRF2 antagonist with IC50 of 1.3 nM; >500 nM for CRF1. Aids gastric emptying.

Formula: C₁₈₃H₃₀₇N₄₉O₅₃

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 4041.69

Ref: TM-TP2095

Astressin 2B

CAS: 681260-70-8

Astressin 2B is a synthetic peptide that is derived from the amino acid sequence of the human protein vasopressin. It has been shown to inhibit the production of proinflammatory cytokines and chemoattractant proteins in experimental models. Astressin 2B also has an effect on intestinal motility by increasing the release of dopamine, which binds to receptors in smooth muscle cells and causes relaxation. Astressin 2B also inhibits cellular physiologic processes related to neuronal death and disease activity, as well as carcinoma cell lines. Astressin 2B has been shown to have cardiac effects, such as increased heart rate and contractility, when administered intravenously at high doses or injected into cardiac tissue. The activity index for astressin 2B is higher than that for other vasopressin-derived peptides, but lower than that for native vasopressin. Astressin 2B also inhibits cyclase activity and glutamate release.

Formula: C₁₈₃H₃₀₇N₄₉O₅₃

Purezza: Min. 95 Area-%

Colore e forma: Powder

Peso molecolare: 4,042 g/mol

Ref: 3D-GCB26070