CAS 68406-26-8

Ginsenoside Rb3

Descrizione:

Ginsenoside Rb3 è una saponina triterpenoide che si trova principalmente nel ginseng, una pianta rinomata per le sue proprietà medicinali. È uno dei molti ginsenosidi, che sono i composti attivi che si ritiene contribuiscano ai benefici per la salute del ginseng. Ginsenoside Rb3 è caratterizzato dalla sua complessa struttura molecolare, che include uno scheletro simile a uno steroide con più moieties di zucchero attaccate, influenzando la sua solubilità e bioattività. Questo composto è noto per i suoi potenziali effetti farmacologici, comprese le proprietà anti-infiammatorie, antiossidanti e neuroprotettive. La ricerca suggerisce che Ginsenoside Rb3 possa migliorare la funzione cognitiva ed esibire effetti cardioprotettivi, rendendolo di interesse sia nella medicina tradizionale che nella farmacologia moderna. Il suo meccanismo d'azione spesso implica la modulazione di vari percorsi di segnalazione, contribuendo al suo potenziale terapeutico. Come molti composti naturali, la biodisponibilità e l'efficacia di Ginsenoside Rb3 possono essere influenzate da fattori come dosaggio, formulazione e differenze metaboliche individuali.

Formula: C₅₃H₉₀O₂₂

InChI: InChI=1/C53H90O22/c1-8-23(2)10-9-15-53(7,75-48-44(67)40(63)38(61)31(72-48)22-69-46-42(65)35(58)28(57)21-68-46)25-13-16-52(6)24-11-12-32-50(3,4)33(14-17-51(32,5)26(24)18-27(56)34(25)52)73-49-45(41(64)37(60)30(20-55)71-49)74-47-43(66)39(62)36(59)29(19-54)70-47/h10,24-49,54-67H,8-9,11-22H2,1-7H3/b23-10+/t24?,25?,26?,27-,28+,29+,30+,31+,32?,33?,34?,35-,36+,37+,38+,39-,40+,41-,42+,43+,44+,45+,46-,47-,48-,49-,51+,52+,53+/m0/s1

InChI key: InChIKey=NODILNFGTFIURN-USYOXQFSSA-N

SMILES: C[C@]12[C@@]3(C)[C@@]([C@@]([C@@](O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@@H](O)[C@H](O)CO5)[C@@H](O)[C@H](O)[C@H]4O)(CCC=C(C)C)C)(CC3)[H])([C@H](O)C[C@@]1([C@]6(C)[C@@](CC2)(C(C)(C)[C@@H](O[C@H]7[C@H](O[C@@H]8O[C@H](CO)[C@@H](O)[C@H](O)[C@H]8O)[C@@H](O)[C@H](O)[C@@H](CO)O7)CC6)[H])[H])[H]

Sinonimi:

• (1R,4E)-1-{(8xi,9xi,12α,13xi,14β)-3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxy-4,4,10,14-tetramethylgonan-17-yl}-1,5-dimethylhept-4-en-1-yl 6-O-β-D-xylopyranosyl-β-D-allopyranoside
• (3β,12β)-3-[(2-O-β-<span class="text-smallcaps">D</smallcap>-Glucopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-<smallcap>D</smallcap>-xylopyranosyl-β-<smallcap>D</span>-glucopyranoside
• Dammarane, β-<span class="text-smallcaps">D</span>-glucopyranoside deriv.
• Ginsenoside Rb₃
• Gypenoside IV
• alpha-D-Glucopyranoside, (3-beta,12-beta)-3-((2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy)-12-hydroxydammar-24-en-20-yl 6-O-beta-D-xylopyranosyl-
• β-<span class="text-smallcaps">D</smallcap>-Glucopyranoside, (3β,12β)-3-[(2-O-β-<smallcap>D</smallcap>-glucopyranosyl-β-<smallcap>D</smallcap>-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-<smallcap>D</span>-xylopyranosyl-
• β-D-Glucopyranoside, (3β,12β)-3-[(2-O-β-D-glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-D-xylopyranosyl-
• Dammarane, β-D-glucopyranoside deriv.
• (3β,12β)-3-[(2-O-β-D-Glucopyranosyl-β-D-glucopyranosyl)oxy]-12-hydroxydammar-24-en-20-yl 6-O-β-D-xylopyranosyl-β-D-glucopyranoside
• Ginsenoside Rb3
• β-D-Glucopyranoside, (3β,12β)-3-[(2-O-β-D-
• NH25835
• Ginsenoside Rb3 ,98%
• [3β-[[2-O-(β-D-Glucopyranosyl)-β-D-glucopyranosyl]oxy]-12β-hydroxy-5α-dammar-24-en-20-yl]6-O-(β-D-xylopyranosyl)-β-D-glucopyranoside
• glucopyranosyl)oxy)-12-hydroxydammar-24-en-20-yl6-o-beta-d-xylopyranosyl-
• xylopyranosyl-
• (3-beta,12-beta)-3-((2-o-beta-d-glucopyranosyl-beta-d-alpha-d-glucopyranosid
• Ginsenoside Rb3, 98%, from Panax ginseng C. A. Mey.
• GINSENOSIDE Rb3(SH)
• (2S,3R,4S,5S,6R)-2-[[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(10R,12S,14R)-12-hydroxy-4,4,10,14-tetramethyl-17-[(E,2R)-6-methyl-2-[[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-[[(2S,3R,4S,5R)-3,4
• hydroxydammar-24-en-20-yl6-O-β-D-

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₅₃H₉₀O₂₂

Purezza: (HPLC) ≥97%

Colore e forma: Powder

Peso molecolare: 1079.29

Ref: 11-0151S

Ginsenoside Rb3

CAS: 68406-26-8

Formula: C₅₃H₉₀O₂₂

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 1079.27

Ref: 7W-GC9541

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 has anti-myocardial ischemia-reperfusion injury, neuroprotective, antidepressant-like, and antioxidant effects, it also possesses the potential of the clinical use in preventing and treating diabetes. Ginsenoside Rb3 significantly attenuates the changes of creatine kinase activity and lactate dehydrogenase activity, exhibits inhibitory effect on TNFα-induced NF-κB transcriptional activity with an IC50 of 8.2 μM in 293T cell lines, it also inhibits the induction of COX-2 and iNOS mRNA.

Formula: C₅₃H₉₀O₂₂

Purezza: 95%~99%

Peso molecolare: 1079.28

Ref: BP-BP0659

Ginsenoside Rb3

CAS: 68406-26-8

Formula: C₅₃H₉₀O₂₂

Peso molecolare: 1079.28

Ref: 4Z-G-157024

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 (Gypenoside IV) is a natural triterpenoid saponin, exhibiting inhibition effect on TNFα-induced NF-κB transcriptional activity.

Formula: C₅₃H₉₀O₂₂

Purezza: 98% - 99.98%

Colore e forma: Solid

Peso molecolare: 1079.27

Ref: TM-T3918

Ginsenoside rb3

CAS: 68406-26-8

Natural glycoside

Formula: C₅₃H₉₀O₂₂

Purezza: ≥ 90.0 % (HPLC)

Colore e forma: Powder

Peso molecolare: 1079.29

Ref: 5G-89679

Ginsenoside Rb3

Prodotto controllato

CAS: 68406-26-8

Stability Hygroscopic
Applications Ginsenoside Rb3 inhibits the upregulation of phospho-IκB-α and nuclear translocation of NF-κB subunit p65 induced by glucose deprivation then reperfusion.
References Ma, L., et. al.: PloS One, 9, e103628/1-e103628/12 (2014)

Formula: C₅₃H₉₀O₂₂

Colore e forma: Neat

Peso molecolare: 1079.27

Ref: TR-G387610

Ginsenoside Rb3

CAS: 68406-26-8

Ginsenoside Rb3 is a natural saponin compound, which is a type of ginsenoside derived from the root of Panax ginseng. The source of Ginsenoside Rb3, Panax ginseng, is a perennial plant widely utilized in traditional medicine for its pharmacological properties.

Formula: C₅₃H₉₀O₂₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 1,079.27 g/mol

Ref: 3D-OG09286