CAS 6893-02-3

Triiodotironina

Descrizione:

Triiodotironina, comunemente noto come T3, è un ormone tiroideo che svolge un ruolo cruciale nella regolazione del metabolismo, della crescita e dello sviluppo nel corpo. È sintetizzato dalla tiroxina (T4) e contiene tre atomi di iodio, essenziali per la sua attività biologica. Il T3 è una molecola lipofila, che gli consente di attraversare facilmente le membrane cellulari e legarsi ai recettori nucleari, influenzando l'espressione genica e i processi metabolici. L'ormone è prodotto principalmente nella ghiandola tiroidea ed è coinvolto in varie funzioni fisiologiche, tra cui la regolazione della frequenza cardiaca, della temperatura corporea e del dispendio energetico. Il T3 viene tipicamente misurato in contesti clinici per valutare la funzione tiroidea e diagnosticare disturbi come l'ipotiroidismo o l'ipertiroidismo. La sua struttura chimica include un anello fenolico e un gruppo amminico, contribuendo alla sua attività biologica. A causa dei suoi effetti potenti, il T3 è utilizzato anche terapeuticamente in alcune condizioni mediche, ma la sua somministrazione deve essere attentamente monitorata per evitare potenziali effetti collaterali associati all'impatto ormonale tiroideo.

Formula: C₁₅H₁₂I₃NO₄

InChI: InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1

InChI key: InChIKey=AUYYCJSJGJYCDS-LBPRGKRZSA-N

SMILES: O(C1=C(I)C=C(C[C@@H](C(O)=O)N)C=C1I)C2=CC(I)=C(O)C=C2

Sinonimi:

• (2S)-2-Azaniumyl-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate
• (S)-2-Amino-3-(4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl)propanoicacid
• 3',5-Triiodo-L-Thyronin
• 3,3',5-Triiodothyronine
• 3,3′,5-Triiodo-<span class="text-smallcaps">L</span>-thyronine
• 3,3′,5-Triiodothyronine
• 3,5,3'-Triiodothyronine
• 4-(3-Iodo-4-Hydroxyphenoxy)-3,5-Diiodophenylalanine
• 4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine
• 5-Diiodophenyl)-3-(4-(4-Hydroxy-3-Iodophenoxy)-L-Alanin
• <span class="text-smallcaps">L</span>-3,3′,5-Triiodothyronine
• <span class="text-smallcaps">L</span>-Liothyronine
• <span class="text-smallcaps">L</span>-T₃
• <span class="text-smallcaps">L</span>-Triiodothyronine
• <span class="text-smallcaps">L</span>-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, <span class="text-smallcaps">L</span>-
• Alanine, 3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]-, L-
• Cyronine
• Cytomel
• L-3,3',5-Triiodothyronine
• L-3,3,5-Triiodothyronine, Free Acid
• L-3-(4-(4-Hydroxy-3-Iodophenoxy)-3,5-Diiodophenyl)Alanine
• L-Liothyronine
• L-T3
• L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-
• L-triiodothyronine
• Liothyronin
• Liothyronine
• Liotironina
• Nsc 80203
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-<span class="text-smallcaps">L</span>-tyrosine
• O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
• O-(4-hydroxyphenyl)-2,3,5-triiodotyrosine
• T3
• T3 (Hormone)
• T3 (amino acid)
• T₃
• T₃ (Hormone)
• T₃ (amino acid)
• Thyronine, 3,3',5-triiodo-, L-
• Thyronine, 3,3′,5-triiodo-, <span class="text-smallcaps">L</span>-
• Tresitope
• Triiodo-<span class="text-smallcaps">L</span>-thyronine
• Triiodo-L-thyronine
• Triiodothyronine

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow to Light orange powder to crystal

Peso molecolare: 650.98

Ref: 3B-T0453

3,3',5-Triiodo-L-thyronine, 95%

CAS: 6893-02-3

Using video intensification fluorescence microscopy and tetramethylrhodamine (Rho)-labeled 3, 3', 5-triiodo-L-thyronine (T3),the uptake of T3 by cultured mouse fibroblasts was studied. The binding of 3, 3', 5-triiodo-L-thyronine (T3) to GH3 rat pituitary tumor cells was studied at 15 degrees C and

Formula: C₁₅H₁₂I₃NO₄

Purezza: 95%

Colore e forma: White to cream to yellow to pale brown, Powder

Peso molecolare: 650.98

Ref: 02-H34068

Liothyronine

CAS: 6893-02-3

Amino-acid derivatives

Formula: C₁₅H₁₂I₃NO₄

Colore e forma: White Cream Powder

Peso molecolare: 650.79005

Ref: 45-1368008

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 650.9735

Ref: IN-DA0032GT

Liothyronine

CAS: 6893-02-3

Liothyronine

Purezza: ≥98%

Peso molecolare: 650.97g/mol

Ref: 54-BUP15946

3,3’,5-Triiodo-L-Thyronine

CAS: 6893-02-3

3,3’,5-Triiodo-L-Thyronine

Purezza: 97%

Peso molecolare: 650.97g/mol

Ref: 54-OR1010733

3,3'',5-Triiodo-L-thyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purezza: ≥ 98.0%

Colore e forma: White to off-white or faint yellow powder

Peso molecolare: 650.97

Ref: 7W-GE2741

Liothyronine

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Colore e forma: White To Off-White Solid

Peso molecolare: 650.98

Ref: 4Z-T-423

Liothyronine-13C9-15N

CAS: 6893-02-3

Formula: C₆₁₃C₉H₁₂I₃₁₅NO₄

Peso molecolare: 348.36

Ref: 4Z-T-4228

Liothyronine

CAS: 6893-02-3

Liothyronine (Tresitope) is an active form of thyroid hormone, binding to β1 thyroid hormone receptor (TRβ1), and activates its activity.

Formula: C₁₅H₁₂I₃NO₄

Purezza: 98.61% - 99.33%

Colore e forma: Crystals Solid

Peso molecolare: 650.97

Ref: TM-T1653

3,3',5-Triiodo-L-thyronine

Prodotto controllato

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Colore e forma: White To Off-White

Peso molecolare: 650.97

Ref: TR-T795380

3,3,5-Triiodo-L-Thyronine extrapure, 95%

CAS: 6893-02-3

Formula: C₁₅H₁₂I₃NO₄

Purezza: min. 95%

Colore e forma: White to off-white, Powder

Peso molecolare: 650.98

Ref: SR-35241

Liothyronine

CAS: 6893-02-3

Purezza: 98%

Peso molecolare: 650.9769897

Ref: 10-F787598

3,3',5-Triiodo-L-thyronine

CAS: 6893-02-3

Triiodothyronine (T3) is a thyroid hormone that has a high affinity for the thyrotropin receptor. It regulates the metabolic rate, cell specific transcriptional regulation, and transcriptional regulation of genes involved in fatty acid synthesis. T3 is synthesized from the amino acid tyrosine through a series of reactions catalyzed by enzymes such as tyrosine hydroxylase, thyroperoxidase, and type 2 iodothyronine deiodinase. The enzyme thyroid peroxidase converts inactive T3 to the active form of T3 (triiodothyronine). In addition, triiodothyronine can be converted to reverse T3 (rT3), which is inactive. Triiodothyronine has an optimal ph of 7.4-8.0 and an optimum igf-i concentration of 100 ng/ml, where it can stimulate growth hormone release from the anterior pituitary gland.

Formula: C₁₅H₁₂I₃NO₄

Purezza: Min. 95 Area-%

Colore e forma: Off-White Powder

Peso molecolare: 650.97 g/mol

Ref: 3D-FT28506