CAS 69-22-7

Citrato di caffeina

Descrizione:

Citrato di caffeina è un composto chimico che combina caffeina, uno stimolante del sistema nervoso centrale, con acido citrico. È utilizzato principalmente in contesti medici, in particolare per il trattamento dell'apnea nei neonati prematuri, poiché aiuta a stimolare la respirazione. Citrato di caffeina è una polvere cristallina bianca o bianco sporco che è solubile in acqua, il che facilita la sua somministrazione in ambienti clinici. Il composto presenta le proprietà stimolanti della caffeina, promuovendo la vigilanza e riducendo la fatica. La sua farmacocinetica comporta un rapido assorbimento e metabolismo nel fegato, portando a un aumento delle concentrazioni plasmatiche di caffeina. Il componente citrato migliora la solubilità e la biodisponibilità della caffeina, rendendola più efficace per l'uso terapeutico. Citrato di caffeina è generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere aumento della frequenza cardiaca, disturbi gastrointestinali e nervosismo, in particolare a dosi più elevate. Come per qualsiasi farmaco, è importante utilizzare Citrato di caffeina sotto supervisione medica per garantire sicurezza ed efficacia.

Formula: C₁₄H₁₈N₄O₉

InChI: InChI=1/C8H10N4O2.C6H8O7/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2;7-3(8)1-6(13,5(11)12)2-4(9)10/h4H,1-3H3;13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=RCQXSQPPHJPGOF-UHFFFAOYSA-N

SMILES: C(CC(O)=O)(CC(O)=O)(C(O)=O)O.O=C1C2=C(N(C)C(=O)N1C)N=CN2C

Sinonimi:

• 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1H-purine-2,6-dione
• 1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-, mixt. contg.
• 1H-purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1) (salt)
• Cafcit
• Caffeina citrate
• Caffeine Citrated
• Caffeine citrate
• Caffeine citrate (1:1)
• Caffeine, citrated [USAN]
• Cafnea
• Citrated caffein
• Citrated caffeine
• Citric acid, compd. with caffeine (1:1)
• Gencebok
• Peyona
• 1,3,7-Trimethyl-3,7-dihydro-1H-purine-2,6-dione 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 1,3,7-TRIMETHYL-2,6-DIOXOPURINE CITRATE
• 1,3,7-Trimethyl-3,7-dihydro-purin-2,6-dion2-hydroxypropane-1,2,3-tricarboxylic acid,1,3,7-trimethyl
• thyl-1h-purine-2,6-dione
• 1,3,7-TRIMETHYLXANTHINE CITRATE
• Coffeinum-citrate
• citricacid,compd.withcaffeine(1:1)
• caffeinecitrate(1:1)
• CAFFEINE CITRATED GRANULAR
• caffeinacitrate
• Kaffein,Citrat
• COFFEINE CITRATE
• METHYLTHEOBROMINE CITRATE
• Caffeine Citrate USP
• Mixture with citric acid
• CAFFEINE,CITRATED,POWDER,PURIFIED
• GUARANINE CITRATE
• Caffeine, Citrated, Powder
• 2-HYDROXYPROPANE-1,2,3-TRICARBOXYLIC ACID,1,3,7-TRIMETHYLPURINE-2,6-DIONE
• citratedcaffein

Caffeine Citrate

Prodotto controllato

CAS: 69-22-7

Formula: C₈H₁₀N₄O₂·C₆H₈O₇

Colore e forma: Neat

Peso molecolare: 386.31

Ref: 86-MM1851.00

Caffeine Citrate

CAS: 69-22-7

Formula: C₈H₁₀N₄O₂C₆H₈O₇

Peso molecolare: 194.2 : 192.1

Ref: ST-EA-CP-C47008

Caffeine citrate

Prodotto controllato

CAS: 69-22-7

Caffeine citrate is a low-dose caffeine product that has been shown to increase locomotor activity in rats. Caffeine citrate is an ester of caffeine and citric acid. It inhibits the enzyme that breaks down acetylcholine, which may lead to an increase in brain functions. Caffeine citrate is used as a treatment for apnea in pediatric patients, and it has also been shown to prevent bacterial translocation and reduce liver impairment caused by certain drugs. The therapeutic effect of caffeine citrate may be due to its ability to inhibit mitochondrial membrane potential, or its effects on basic proteins such as sodium citrate, or both.

Formula: C₈H₁₀N₄O₂·C₆H₈O₇

Colore e forma: White Powder

Peso molecolare: 386.31 g/mol

Ref: 3D-FC35311

Caffeine Citrate

CAS: 69-22-7

Applications Caffeine citrate (Cafcit) is a citrate salt of Caffeine, sometimes used in medical treatment, including short-term treatment of apnea of prematurity (lack of breathing in premature infants). Caffeine citrate functions in much the same capacity as does caffeine, but takes effect more quickly; its speed of dissociation is faster than that of Caffeine. Caffeine citrate is typically only used to treat severe migraines.
References Zubair, U.M., et al.: Anal. Profiles Drug Subs., 15, 71 (1986); Cherrah, Y., et al.: Biochem. Pharmacol., 37, 1311 (1988); Grillon, C., et al.: Clin. Neurophysiol., 114, 1557 (2003); Duangdao, D., et al.: Behav. Brain Res., 205, 1 (2009);

Formula: C₈H₁₀N₄O₂·C₆H₈O₇

Colore e forma: White

Peso molecolare: 386.31

Ref: TR-C080115

Caffeine Citrate

CAS: 69-22-7

Colore e forma: Neat

Ref: 61-FOR1851.00