CAS 696-04-8

Diidrotimina

Descrizione:

Diidrotimina, con il numero CAS 696-04-8, è un derivato della pirimidina e una forma ridotta della timina, una delle quattro nucleobasi nel DNA. È caratterizzato dalla presenza di due atomi di idrogeno aggiuntivi, che risultano in una struttura saturata rispetto alla natura insatura della timina. Diidrotimina è tipicamente un solido cristallino bianco a bianco sporco, ed è solubile in solventi polari come acqua e alcoli. Il composto è di interesse nella ricerca biochimica, in particolare negli studi relativi alla riparazione del DNA e agli effetti dello stress ossidativo sulle nucleobasi. La sua struttura ridotta può influenzare la stabilità e la reattività degli acidi nucleici, rendendolo un argomento rilevante nei campi della biologia molecolare e della chimica medicinale. Inoltre, Diidrotimina può servire come composto modello per comprendere i meccanismi di danno e riparazione del DNA, così come lo sviluppo di agenti terapeutici mirati alle interazioni degli acidi nucleici.

Formula: C₅H₈N₂O₂

InChI: InChI=1S/C5H8N2O2/c1-3-2-6-5(9)7-4(3)8/h3H,2H2,1H3,(H2,6,7,8,9)

InChI key: InChIKey=NBAKTGXDIBVZOO-UHFFFAOYSA-N

SMILES: O=C1C(C)CNC(=O)N1

Sinonimi:

• (5R)-5-methyldihydropyrimidine-2,4(1H,3H)-dione
• (5S)-5-methyldihydropyrimidine-2,4(1H,3H)-dione
• 2,4(1H,3H)-Pyrimidinedione, dihydro-5-methyl-
• 2-Hydroxy-5-methyl-5,6-dihydro-1H-pyrimidin-4-one
• 5,6-Dihydro-5-methyluracil
• 5,6-Dihydrothymine
• 5-Methyl-5,6-dihydrouracil
• 5-methyldihydropyrimidine-2,4(1H,3H)-dione
• Dihydro-5-methyl-2,4(1H,3H)-pyrimidinedione
• Dihydrothymine
• Hydrouracil, 5-methyl-

5,6-Dihydro-5-methyluracil, 98+%

CAS: 696-04-8

5,6-Dihydro-5-methyluracil, is used as an active pharmaceutical ingredient. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or S

Formula: C₅H₈N₂O₂

Purezza: 98+%

Colore e forma: Crystals or crystalline powder, White to pale cream

Peso molecolare: 128.13

Ref: 02-L01996

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

Formula: C₅H₈N₂O₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 128.1292

Ref: IN-DA003MA0

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.

Formula: C₅H₈N₂O₂

Purezza: 98.53%

Colore e forma: Solid

Peso molecolare: 128.13

Ref: TM-T0532

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

5,6-Dihydro-5-methyluracil

Purezza: ≥98%

Peso molecolare: 128.13g/mol

Ref: 54-BUP14147

5,6-Dihydro-5-methyluracil

CAS: 696-04-8

5,6-Dihydro-5-methyluracil

Purezza: 97%

Peso molecolare: 128.13g/mol

Ref: 54-OR1026137

5,6-Dihydrothymine-α,alphaalpha,5,6,6-d6 -6

CAS: 334473-42-6, 696-04-8

Purezza: 99 atom % D

Peso molecolare: 134.17

Ref: 3U-D7687

5,6-Dihydro Thymine

Prodotto controllato

CAS: 696-04-8

Applications 5,6-Dihydrothymine is a derivative of Thymine, a nucleobase in the nucleic acid of DNA . 5,6-Dihydrothymine is a radiolysis product of DNA.
References Hubbard, K. et al.: Biochemistry, 28, 4382 (1989); Cadet, J. et al.: Int. J. Rad. Biol. Rel. Stud. Phys. Chem. Med., 39, 119 (1981);

Formula: C₅H₈N₂O₂

Colore e forma: Neat

Peso molecolare: 128.13

Ref: TR-D449440

5-Methyl-dihydro-pyrimidine-2,4-dione

CAS: 696-04-8

Formula: C₅H₈N₂O₂

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 128.131

Ref: 10-F487619

5,6-Dihydro Thymine

CAS: 696-04-8

5,6-Dihydrothymine is a metabolic precursor to thymine. It has been shown to inhibit the production of DNA and RNA in cells, which causes cellular transformation. 5,6-Dihydrothymine also inhibits enzyme activity by competing with substrates or by forming covalent bonds with the enzyme. This drug has been found to be genotoxic and may cause cancer, but it can also be used for diagnosis and treatment of radiation-induced genetic damage. The drug is an oral prodrug that is hydrolyzed in the gastrointestinal tract to release thymine. 5,6-Dihydrothymine is used for molecular pathogenesis studies on solid tumours, such as breast cancer and prostate cancer.

Formula: C₅H₈N₂O₂

Purezza: Min. 95%

Peso molecolare: 128.13 g/mol

Ref: 3D-AAA69604