CAS 69739-16-8

Cefodizima

Descrizione:

Cefodizima è un antibiotico cefalosporinico ad ampio spettro, classificato sotto la terza generazione di cefalosporine. È utilizzato principalmente per il trattamento di varie infezioni batteriche grazie alla sua efficacia contro batteri sia Gram-positivi che Gram-negativi. Cefodizima agisce inibendo la sintesi della parete cellulare batterica, portando alla lisi cellulare e alla morte. Il composto è caratterizzato dalla sua stabilità contro alcune beta-lattamasi, il che ne migliora l'efficacia contro ceppi resistenti. Viene tipicamente somministrato per iniezione e ha un profilo farmacocinetico favorevole, che consente una penetrazione efficace nei tessuti. Le indicazioni comuni per Cefodizima includono infezioni delle vie respiratorie, infezioni delle vie urinarie e infezioni cutanee. Come con altri antibiotici, è essenziale utilizzare Cefodizima con cautela per ridurre al minimo il rischio di sviluppare resistenza agli antibiotici. Gli effetti collaterali potenziali possono includere reazioni allergiche, disturbi gastrointestinali e alterazioni nei parametri ematici. In generale, Cefodizima rappresenta un'opzione preziosa nell'arsenale delle terapie antimicrobiche, in particolare in contesti in cui la resistenza ad altri antibiotici è una preoccupazione.

Formula: C₂₀H₂₀N₆O₇S₄

InChI: InChI=1/C20H20N6O7S4/c1-7-10(3-11(27)28)37-20(22-7)36-5-8-4-34-17-13(16(30)26(17)14(8)18(31)32)24-15(29)12(25-33-2)9-6-35-19(21)23-9/h6,13,17H,3-5H2,1-2H3,(H2,21,23)(H,24,29)(H,27,28)(H,31,32)/b25-12+/t13-,17-/m1/s1

InChI key: InChIKey=XDZKBRJLTGRPSS-BGZQYGJUSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C=3N=C(N)SC3)=O)C2=O)(SCC1CSC=4SC(CC(O)=O)=C(C)N4)[H]

Sinonimi:

• (6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-({[5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-
• 7-(((2-Amino-4-Thiazolyl)(Methoxyimino)Acetyl)Amino)-3-(((5-(Carboxymethyl)-4-Methyl-2-Thiazolyl)Thio)Methyl)-8-Oxo-5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylic Acid
• 7-(α-(Z)-Methoxyimino-α-(2-aminothiazol-4-yl)acetamido)-3-((5-carboxymethyl-4-methylthiazol-2-yl)thiomethyl)-3-cephem-4-carboxylic acid
• Cefodizime acid
• Cefodizime
• FIR-221

5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid,7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[[5-(carboxymethyl)-4-methyl-2-thiazolyl]thio]methyl]-8-oxo-, (6R,7R)-

CAS: 69739-16-8

Formula: C₂₀H₂₀N₆O₇S₄

Purezza: 97%

Colore e forma: Solid

Peso molecolare: 584.6688

Ref: IN-DA01CCIC

Cefodizime

CAS: 69739-16-8

Cefodizime

Purezza: ≥98%

Peso molecolare: 584.67g/mol

Ref: 54-BUP13742

Cefodizime

CAS: 69739-16-8

Formula: C₂₀H₂₀N₆O₇S₄

Peso molecolare: 584.66

Ref: 4Z-C-313001

Cefodizime

CAS: 69739-16-8

Cefodizime: a new, well-tolerated cephalosporin antibiotic with immunomodulatory properties for serious respiratory and urinary infections.

Formula: C₂₀H₂₀N₆O₇S₄

Purezza: 99.62%

Colore e forma: Solid

Peso molecolare: 584.67

Ref: TM-T14922

Cefodizime

CAS: 69739-16-8

Applications Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime maybe useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections.
References Barradel, L.B. et al.: Drugs, 44, 800 (1992); Kasai, K. et al.: Jap. J. Antibiot., 37, 1306 (1984);

Formula: C₂₀H₂₀N₆O₇S₄

Colore e forma: Neat

Peso molecolare: 584.67

Ref: TR-C242865

Cefodizime

CAS: 69739-16-8

Cefodizime is a third-generation cephalosporin antibiotic, which is derived from the fungus Acremonium. It exerts its bactericidal effects by inhibiting bacterial cell wall synthesis. This action is achieved through binding to penicillin-binding proteins (PBPs), leading to the interruption of peptidoglycan cross-linking essential for the bacterial cell wall integrity. The breakdown of cell wall synthesis results in the lysis and death of the bacterial cell.

Purezza: Min. 95%

Ref: 3D-FC35157