CAS 70255-72-0

Adenosine-2-carboxamide

CAS: 70255-72-0

Adenosine-2-carboxamide is a Nucleoside Derivative - 2-Modified purine nucleoside.

Formula: C₁₁H₁₄N₆O₅

Colore e forma: Solid

Peso molecolare: 310.27

Ref: TM-TNU0298

Adenosine-2-carboxamide

CAS: 70255-72-0

Adenosine-2-carboxamide (ACA) is a potent and selective adenosine A2A receptor ligand with high affinity and selectivity. This drug has been shown to be a competitive antagonist of the adenosine A2A receptor with an IC50 of 0.8 nM and was highly selective for this receptor over the other adenosine receptors. ACA has also been shown to inhibit binding of radioligands to the adenosine A2A receptor in functional assays, as well as improve binding activity in cell-based assays. These results were confirmed by in silico studies that showed ACA to have high binding affinity, low off-target activity, and good pharmacokinetic properties.

Purezza: Min. 95%

Ref: 3D-NA162961