CAS 70288-86-7

Ivermectina

Descrizione:

Ivermectina è un agente antiparassitario ad ampio spettro utilizzato principalmente in medicina veterinaria e nella salute umana per il trattamento di varie infezioni parassitarie. Appartiene alla classe delle lattone macrocicliche ed è derivato dal batterio Streptomyces avermitilis. Il composto presenta una struttura complessa caratterizzata da un grande anello di lattone e da più stereocentri, contribuendo alla sua attività biologica. Ivermectina agisce legandosi ai canali del cloruro attivati dal glutammato nelle cellule nervose e muscolari dei parassiti, portando alla paralisi e alla morte dell'organismo. È efficace contro una gamma di parassiti, inclusi quelli che causano cecità fluviale, filariosi linfatica e scabbia. Ivermectina è generalmente ben tollerato, con un profilo di sicurezza favorevole, sebbene possano verificarsi effetti collaterali, in particolare nei casi di alta carica parassitaria. Il suo utilizzo si è espanso oltre le applicazioni tradizionali, con ricerche in corso che esplorano le sue potenziali proprietà antivirali. Il composto è tipicamente somministrato per via orale o topica, a seconda del tipo di infezione trattata.

Formula: Unspecified

InChI: InChI=1/C48H74O14.C47H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38;1-24(2)41-27(5)16-17-46(61-41)22-33-19-32(60-46)15-14-26(4)42(25(3)12-11-13-31-23-54-44-39(48)28(6)18-34(45(50)57-33)47(31,44)51)58-38-21-36(53-10)43(30(8)56-38)59-37-20-35(52-9)40(49)29(7)55-37/h12-15,19,25-26,28,30-31,33-45,49-50,52H,11,16-18,20-24H2,1-10H3;11-14,18,24-25,27,29-30,32-44,48-49,51H,15-17,19-23H2,1-10H3/b13-12+,27-15+,32-14+;12-11+,26-14+,31-13+/t25?,26-,28-,30-,31-,33+,34?,35-,36-,37-,38?,39-,40+,41-,42-,43+,44-,45+,47+,48+;25-,27-,29-,30-,32+,33?,34-,35-,36-,37?,38-,39+,40-,41+,42-,43-,44+,46+,47+/m00/s1

Sinonimi:

• 22,23-Dihydroavermectin
• 22,23-Dihydroavermectin B1
• 22,23-Dihydroavermectin B₁
• Bagomectina
• Bimectin
• Bovinet
• Cardomec
• Cardotek 30
• Cardotek Plus
• Cevamec
• Equimec
• Equimec Paste
• Equimectrin
• Equirat Gold
• Eqvalan
• Heartgard
• Heartgard 30
• Hyvermectin
• Ivectin
• Ivermec
• Ivermectin B1a-ivermectin B1b mixture
• Ivermectin Injection
• Ivermectina
• Ivermectine
• Iversalt
• Ivertin
• Ivomec
• Ivomec Gold
• Ivosint
• Jetamec
• L 640471
• Mectizan
• Mk 933
• Mk-0933
• Mukhnet I
• Noramectin
• Noromectin
• Oramec
• Oramectin
• Pandex
• Phoenectin
• Solantra
• Soolantra
• Stromectol
• Uvemec
• Vermic
• Vetmec
• Virbamec LA
• Zimecterin

Ivermectin

CAS: 70288-86-7

Formula: C₄₈H₇₄O₁₄

Purezza: >93.0%(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 875.11

Ref: 3B-I0819

Ivermectin

CAS: 70288-86-7

It is used as a positive allosteric modulator of the 7 neuronal nicotinic acetylcholine receptor. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar p

Formula: C₉₅H₁₄₆O₂₈

Colore e forma: Powder, White to pale cream

Peso molecolare: 1736.19

Ref: 02-J62777

Ivermectin

CAS: 70288-86-7

Ivermectin

Formula: C₄₈H₇₄O₁₄

Purezza: 87.6%

Colore e forma: White To Off-White

Peso molecolare: 874.50786

Ref: 47-864

IVERMECTIN RS

CAS: 70288-86-7

IVERMECTIN RS

Ref: 41-ICRS73066

IVERMECTIN CRS

CAS: 70288-86-7

IVERMECTIN CRS

Formula: C₉₅H₁₄₆O₂₈

Colore e forma: Powder

Ref: 41-I8000010

Ivermectin

CAS: 70288-86-7

Lactones, nesoi

Formula: H₂B₁a(C₄₈H₇₄O₁₄)H₂B₁b(C₄₇H₇₂O₁₄)

Colore e forma: White Light Yellow Crystalline Powder

Ref: 45-1354309

Ivermectin

CAS: 70288-86-7

Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.

Formula: C₄₈H₇₄O₁₄

Purezza: 94.11% - 99.71%

Colore e forma: Solid

Peso molecolare: 875.09

Ref: TM-T1131

Ivermectin (Mixture of B1a and B1b)

CAS: 70288-86-7

Formula: C₄₈H₇₄O₁₄B₁aC₄₇H₇₂O₁₄B₁b

Peso molecolare: 875.11 (B1a) 861.08 (B1b)

Ref: 4Z-I-077001

Ivermectin

CAS: 70288-86-7

Formula: C₄₈H₇₄O₁₄(H₂B₁a)

Purezza: ≥ 95.0% (dry basis, H2B1a + H2B1b)

Colore e forma: White to light-yellow crystalline powder

Peso molecolare: 875.11 (H2B1a)

Ref: 7W-GA9725

Ivermectine 100 µg/mL in Acetonitrile

CAS: 70288-86-7

Formula: C₄₈H₇₄O₁₄·C₄₇H₇₂O₁₄

Colore e forma: Single Solution

Peso molecolare: 1736.16

Ref: 04-XA14488000AL

LC PestiMix 4 10 µg/mL in Acetonitrile

CAS: 103055-07-8, 10311-84-9, 103112-35-2, 113614-08-7, 114-26-1, 114369-43-6, 1172134-12-1, 117428-22-5, 117704-25-3, 120983-64-4, 1216-44-0, 122836-35-5, 123997-26-2, 125225-28-7, 126833-17-8, 129558-76-5, 129630-19-9, 13067-93-1, 13141-86-1, 131983-72-7, 135590-91-9, 13684-63-4, 137641-05-5, 14255-72-2, 142891-20-1, 143807-66-3, 149961-52-4, 163520-33-0, 165108-07-6, 179101-81-6, 189278-12-4, 19044-88-3, 203313-25-1, 220899-03-6, 2274-67-1, 229977-93-9, 2303-17-5, 23031-36-9, 2314-09-2, 24353-61-5, 2439-01-2, 24691-80-3, 2600-69-3, 2655-15-4, 26644-46-2, 30558-43-1, 31251-03-3, 33399-00-7, 35256-85-0, 35575-96-3, 3761-41-9, 38083-17-9, 39184-27-5, 39184-59-3, 40487-42-1, 42509-80-8, 50512-35-1, 50563-36-5, 51218-49-6, 5131-24-8, 54406-48-3, 555-37-3, 56425-91-3, 581809-46-3, 60-51-5, 60207-31-0, 60238-56-4, 6132-17-8, 6552-21-2, 69581-33-5, 70124-77-5, 70288-86-7, 71751-41-2, 7292-16-2, 76674-21-0, 78-34-2, 79622-59-6, 81406-37-3, 83121-18-0, 83657-24-3, 86-50-0, 86479-06-3, 87237-48-7, 87674-68-8, 95617-09-7, 98730-04-2, 98886-44-3, 99607-70-2

Colore e forma: Mixture

Ref: 04-A50000804AL

Ivermectine

Prodotto controllato

CAS: 70288-86-7

Formula: C₄₈H₇₄O₁₄·C₄₇H₇₂O₁₄

Colore e forma: Neat

Peso molecolare: 1736.16

Ref: 04-CA14488000

PharmaVetResiMix 1 Avermectins-v6 10 µg/mL in Methanol

Prodotto controllato

CAS: 113507-06-5, 117704-25-3, 123997-26-2, 155569-91-8, 70288-86-7, 71751-41-2

Colore e forma: Mixture

Ref: 04-A30000031ME

Smart Solutions™ v59 PharmaVetResiMix Kit 1

CAS: 100-90-3, 113507-06-5, 115550-35-1, 117704-25-3, 119478-55-6, 122-11-2, 1220-83-3, 123997-26-2, 127-71-9, 127-79-7, 144-82-1, 144-83-2, 14698-29-4, 148-79-8, 149676-40-4, 155569-91-8, 19562-30-2, 20559-55-1, 2447-57-6, 28657-80-9, 31430-15-6, 31431-39-7, 389-08-2, 42835-25-6, 43210-67-9, 515-64-0, 51940-44-4, 53716-50-0, 54029-12-8, 54965-21-8, 57-67-0, 57-68-1, 58306-30-2, 59-40-5, 63-74-1, 651-06-9, 68-35-9, 68786-66-3, 70288-86-7, 70458-96-7, 71751-41-2, 72-14-0, 723-46-6, 729-99-7, 74011-58-8, 75184-71-3, 79660-72-3, 80-08-0, 80-32-0, 80-35-3, 80983-34-2, 82419-36-1, 85721-33-1, 88254-99-3, 91296-86-5, 91296-87-6, 93106-60-6, 948-71-0, 98079-52-8

Colore e forma: Mixture

Ref: 04-K30000030

GB 23200.121-2021 Pesticide Mixture 8 50 µg/mL in Acetonitrile:Methanol

Prodotto controllato

CAS: 101205-02-1, 107534-96-3, 111479-05-1, 111988-49-9, 117428-22-5, 119446-68-3, 121-21-1, 129630-19-9, 131860-33-8, 133855-98-8, 134098-61-6, 135186-78-6, 143390-89-0, 148477-71-8, 153233-91-1, 153719-23-4, 19666-30-9, 2312-35-8, 238410-11-2, 283594-90-1, 28434-01-7, 39300-45-3, 39515-41-8, 40596-69-8, 50512-35-1, 51-03-6, 51338-27-3, 51630-58-1, 52645-53-1, 52918-63-5, 55179-31-2, 55219-65-3, 69806-50-4, 70288-86-7, 76578-14-8, 77501-63-4, 77501-90-7, 80844-07-1, 82657-04-3, 83-79-4, 83657-24-3, 850881-70-8, 88671-89-0, 935545-74-7, 94361-06-5, 95737-68-1

Colore e forma: Mixture

Ref: 04-A50000728MC

Ivermectin-d2

Prodotto controllato

CAS: 70288-86-7

Applications Isotope labelled Ivermectin, is the labeled analogue of Ivermectin (I940800), which is a semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Antihelmintic (Onchocerca). An invitro inhibitor of SARS-CoV-2/ Covid-19.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980), Campbell, W.C., et al.: Science, 221, 823 (1983), Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988), Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995), ; Caly, L., et al.: Antivir. Res., 178

Formula: C₄₈H₇₂D₂O₁₄

Colore e forma: Neat

Peso molecolare: 877.11

Ref: TR-I940802

Ivermectin

Prodotto controllato

CAS: 70288-86-7

Applications Semi-synthetic derivative of Abamectin; consists of a mixture of not less than 80% component B1a and not more than 20% component B1b. Anthelmintic (Onchocerca).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chabala, J.C., et al.: J. Med. Chem., 23, 1134 (1980); Campbell, W.C., et al.: Science, 221, 823 (1983); Bennett, J.L., et al.: Parasitol. Today, 4, 226 (1988); Plaisier, A.P., et al.: J. Infect. Dis., 172, 204 (1995);

Formula: C₄₈H₇₄O₁₄·C₄₇H₇₂O₁₄

Colore e forma: White To Off-White

Peso molecolare: 1736.16

Ref: TR-I940800

Ivermectin - Bio-X ™

CAS: 70288-86-7

Naturally produced by the soil bacterium Streptomyces avermitili, Ivermectin is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, research indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.

Formula: C₄₈H₇₄O₁₄

Purezza: (%) Min. 95%

Colore e forma: Powder

Peso molecolare: 875.09 g/mol

Ref: 3D-BI166167

Ivermectin

CAS: 70288-86-7

Naturally produced by the soil bacterium Streptomyces avermitili, it is clinically used in the treatment of parasitosis in both humans and animals. Ivermectin is commercially available as a mixture of 80% 22, 23-dihydroavermectin B1a and 20% 22, 23-dihydroavermectin B1b. In 2020, Ivermectin indicated that it was a good antiviral agent in the treatment of SARS-CoV-2 and a new mechanism of action has been suggested. Ivermectin would act on importin α/β heterodimer and affect nuclear transport and the translocation of viral proteins.

Formula: C₄₈H₇₄O₁₄

Purezza: Min. 90 Area-%

Colore e forma: White Yellow Powder

Peso molecolare: 875.09 g/mol

Ref: 3D-FI24744

Ivermectin (IVM), 95-102%

CAS: 70288-86-7

Formula: C₄₈H₇₄O₁₄

Purezza: min. 95 - 102%

Colore e forma: White to off-white, Crystalline powder

Peso molecolare: 875.10

Ref: SR-18443