CAS 71989-18-9

N-(9-Fluorenilmetossicarbonile)-L-acido glutammico γ-terz-butil estere

Descrizione:

N-(9-Fluorenilmetossicarbonile)-L-acido glutammico γ-terz-butil estere, comunemente noto come Fmoc-L-Glu(γ-tBu)-OH, è una forma protetta dell'aminoacido L-acido glutammico. Questo composto è caratterizzato dalla presenza di un gruppo 9-fluorenilmetossicarbonile (Fmoc), che funge da gruppo protettivo per la funzionalità amminica, consentendo reazioni selettive durante la sintesi dei peptidi. Il gruppo estere γ-tert-butile fornisce ulteriore protezione per la parte acida carbossilica, migliorando la stabilità e la solubilità del composto nei solventi organici. Fmoc-L-Glu(γ-tBu)-OH è tipicamente utilizzato nella sintesi di peptidi in fase solida, dove facilita l'assemblaggio passo-passo dei peptidi prevenendo reazioni secondarie indesiderate. Il composto è generalmente stabile in condizioni di laboratorio standard, ma potrebbe richiedere condizioni specifiche per la deprotezione. La sua struttura contribuisce alla sua utilità in biochimica e chimica medicinale, in particolare nella sintesi di peptidi con proprietà funzionali specifiche.

Formula: C₂₄H₂₇NO₆

InChI: InChI=1S/C24H27NO6/c1-24(2,3)31-21(26)13-12-20(22(27)28)25-23(29)30-14-19-17-10-6-4-8-15(17)16-9-5-7-11-18(16)19/h4-11,19-20H,12-14H2,1-3H3,(H,25,29)(H,27,28)/t20-/m0/s1

InChI key: InChIKey=OTKXCALUHMPIGM-FQEVSTJZSA-N

SMILES: C(OC(N[C@@H](CCC(OC(C)(C)C)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentanoic acid
• (2S)-5-(tert-Butoxy)-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)-5-oxopentanoic acid
• (2S)-5-tert-Butoxy-2-(9H-fluoren-9-ylmethoxycarbonylamino)-5-oxo-pentanoic acid
• (2S)-5-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• (4S)-5-tert-butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• 5-tert-butoxy-4-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-5-oxopentanoic acid (non-preferred name)
• <span class="text-smallcaps">L</span>-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester
• FMOC-Glu(OtBu)-OH
• Fmoc-L-glutamic acid 5-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-glutamic acid γ-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)glutamic acid γ-tert-butyl ester
• N-(9-Fluorenylmethoxycarbonyl)-L-glutamic acid γ-tert-butyl ester
• L-Glutamic acid, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-, 5-(1,1-dimethylethyl) ester

N-Fmoc-L-glutamic acid 5-tert-butyl ester, 98%

CAS: 71989-18-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₄H₂₇NO₆

Purezza: 98%

Peso molecolare: 425.48

Ref: 02-H59169

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Formula: C₂₄H₂₇NO₆

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 425.4743

Ref: IN-DA0038GY

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Formula: C₂₄H₂₇NO₆

Purezza: ≥ 99.0%

Colore e forma: White powder

Peso molecolare: 425.48

Ref: 7W-GM7333

Fmoc-L-glutamic acid 5-tert-butyl ester

CAS: 71989-18-9

Fmoc-L-glutamic acid 5-tert-butyl ester

Purezza: ≥98%

Peso molecolare: 425.47g/mol

Ref: 54-BUP19524

5-tert-Butyl N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-glutamate

CAS: 71989-18-9

Formula: C₂₄H₂₇NO₆

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 425.48

Ref: 3B-B3167

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

M03409 - Fmoc-Glu(OtBu)-OH

Formula: C₂₄H₂₇NO₆

Purezza: 99%

Colore e forma: Powder or Crystalline Powder or Solid

Peso molecolare: 425.481

Ref: 10-M03409

Fmoc-L-glutamic acid 5-tert-butyl ester

CAS: 71989-18-9

Fmoc-L-glutamic acid 5-tert-butyl ester (Fmoc-Glu(OtBu)-OH) is a glutamic acid derivative.

Formula: C₂₄H₂₇NO₆

Purezza: 99.68%

Colore e forma: Solid

Peso molecolare: 425.47

Ref: TM-T64329

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fmoc-Glu(OtBu)-OH

Formula: C₂₄H₂₇NO₆

Purezza: 98%

Colore e forma: white powder

Peso molecolare: 425.47g/mol

Ref: 54-OR911397

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Fmoc-Glu(OtBu)-OH is an amino acid that is used in the synthesis of peptides and proteins. It is a hydrophilic, non-polar amino acid with a hydroxyl group at its carboxy terminus. This substance has been shown to inhibit the growth of cancer cells in vitro and has been used for the development of monoclonal antibodies. Fmoc-Glu(OtBu)-OH has also been shown to have pharmacokinetic properties that are different from other amino acids such as L-lysine, which may be due to its hydrophilic interactions with plasma proteins. This compound is also toxic, as shown by studies on rats where it was found to cause liver damage at high doses. Fmoc-Glu(OtBu)-OH binds to receptors on cells known as polysialic acid receptors, which are involved in cell adhesion and migration. Fmoc-Glu

Formula: C₂₄H₂₇NO₆

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 425.47 g/mol

Ref: 3D-FF28968

FMOC-L-Glutamic Acid 5-Tert-Butyl Ester (FMOC-Glu(OtBu)-OH) extrapure, 99%

CAS: 71989-18-9

Formula: C₂₄H₂₇NO₆

Purezza: min. 99%

Colore e forma: White to off-white, Crystalline powder

Peso molecolare: 425.47

Ref: SR-90673

Fmoc-Glu(OtBu)-OH

CAS: 71989-18-9

Formula: C₂₄H₂₇NO₆

Peso molecolare: 425.5

Ref: ST-EA-CP-L28030