CAS 71989-23-6

N-Fmoc-L-isoleucina

Descrizione:

N-Fmoc-L-isoleucina è un derivato dell'aminoacido isoleucina, caratterizzato dalla presenza di un gruppo protettivo 9-fluorenilmetossicarbonile (Fmoc) sul terminus amminico. Questo composto è comunemente utilizzato nella sintesi di peptidi come blocco di costruzione grazie alla sua stabilità e facilità di rimozione del gruppo Fmoc in condizioni basiche lievi. N-Fmoc-L-isoleucina conserva le proprietà essenziali dell'isoleucina, inclusa la sua natura idrofobica e la capacità di partecipare a varie interazioni all'interno delle catene peptidiche. Il gruppo Fmoc migliora la solubilità dell'aminoacido in solventi organici, facilitando la sua incorporazione nei peptidi. Inoltre, N-Fmoc-L-isoleucina è tipicamente bianco a bianco sporco nell'aspetto ed è solubile in comuni solventi organici come dimetilformammide (DMF) e dimetilsolfossido (DMSO). La sua struttura molecolare consente la formazione di legami peptidici stabili, rendendolo un componente prezioso nella sintesi di peptidi e proteine biologicamente attive.

Formula: C₂₁H₂₃NO₄

InChI: InChI=1S/C21H23NO4/c1-3-13(2)19(20(23)24)22-21(25)26-12-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,13,18-19H,3,12H2,1-2H3,(H,22,25)(H,23,24)/t13-,19-/m0/s1

InChI key: InChIKey=QXVFEIPAZSXRGM-DJJJIMSYSA-N

SMILES: C(OC(N[C@@H]([C@H](CC)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2S,3R)-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoate
• (2S,3S)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-methylpentanoic acid
• 2-{[(9H-Fluoren-9-ylmethoxy)carbonyl]amino}-3-methylpentanoic acid
• <span class="text-smallcaps">L</span>-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-Ile-OH
• Fmoc-L-isoleucine
• Fmoc-lle-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">L</span>-isoleucine
• N-(9-Fluorenylmethoxycarbonyl)isoleucine
• N-Fmoc-<span class="text-smallcaps">L</span>-isoleucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-isoleucine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucin
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]isoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alloisoleucine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-isoleucine
• NSC 334289
• isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• N-(9-Fluorenylmethoxycarbonyl)-L-isoleucine
• L-Isoleucine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-L-isoleucine

CAS: 71989-23-6

Formula: C₂₁H₂₃NO₄

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 353.42

Ref: 3B-F0294

Fmoc-Ile-OH

CAS: 71989-23-6

Bachem ID: 4003168.

Formula: C₂₁H₂₃NO₄

Purezza: 99.87%

Colore e forma: White

Peso molecolare: 353.42

Ref: 01-4003168

Fmoc-L-Isoleucine

CAS: 71989-23-6

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 353.4116

Ref: IN-DA0036PS

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH

Purezza: ≥98%

Peso molecolare: 353.41g/mol

Ref: 54-BUP19430

Fmoc-Ile-OH

CAS: 71989-23-6

Formula: C₂₁H₂₃NO₄

Purezza: ≥ 99.0%

Colore e forma: White powder

Peso molecolare: 353.42

Ref: 7W-GM4384

Fmoc-lle-OH

CAS: 71989-23-6

M03362 - Fmoc-lle-OH

Formula: C₂₁H₂₃NO₄

Purezza: 98%

Colore e forma: Powder or Crystalline Powder

Peso molecolare: 353.418

Ref: 10-M03362

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH (Fmoc-L-isoleucine) is an Fmoc-modified isoleucine with a strong affinity for peptides and proteins and can be used to synthesize other active

Formula: C₂₁H₂₃NO₄

Purezza: 99.75%

Colore e forma: Solid

Peso molecolare: 353.41

Ref: TM-T67562

L-Isoleucine, FMOC protected

CAS: 71989-23-6

L-Isoleucine, FMOC protected

Formula: C₂₁H₂₃NO₄

Purezza: 95%

Colore e forma: white powder

Peso molecolare: 353.41g/mol

Ref: 54-OR0490

Fmoc-Ile-OH (N-Fmoc-L-isoleucine)

CAS: 71989-23-6

Formula: C₂₁H₂₃NO₄

Peso molecolare: 353.42

Ref: 4Z-L-117014

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH is a sodium salt that is used in the synthesis of peptides. It provides the hydroxyl group to the peptide chain, and can be used in solid-phase synthesis. The protonated form of Fmoc-Ile-OH is useful for acetonitrile solvents. Fmoc-Ile-OH has shown antibacterial activity against gram-positive bacteria such as Staphylococcus aureus and Streptococcus pneumoniae. Clinical development of this drug has been successful in treating infections caused by multidrug resistant bacteria, such as MRSA, Acinetobacter baumannii, and Pseudomonas aeruginosa.

Formula: C₂₁H₂₃NO₄

Purezza: Min. 98.0 Area-%

Peso molecolare: 353.42 g/mol

Ref: 3D-FLI-1724-PI

FMOC-L-Isoleucine extrapure, 99%

CAS: 71989-23-6

Formula: C₂₁H₂₃NO₄

Purezza: min. 99%

Colore e forma: White, Crystalline powder

Peso molecolare: 353.40

Ref: SR-22834

N-Fmoc-L-isoleucine

Prodotto controllato

CAS: 71989-23-6

Applications N-Fmoc-L-isoleucine is a N-Fmoc-protected form of L-Isoleucine (I820175). L-Isoleucine is classified as an essential amino acid, and is also a tumour promoter of bladder cancer in rats.
References Hatch, T., et al.: Infect. Immun., 12, 211 (1975); Nishio, Y., et al.: Science, 231, 843 (1986)

Formula: C₂₁H₂₃NO₄

Colore e forma: Neat

Peso molecolare: 353.41

Ref: TR-F625025

N-Fmoc-L-isoleucine-d10

Prodotto controllato

CAS: 71989-23-6

Applications N-Fmoc-L-isoleucine-d10 is the labeled analogue of N-Fmoc-L-isoleucine (F625025), a N-Fmoc-protected form of L-Isoleucine (I820175). L-Isoleucine is classified as an essential amino acid, and is also a tumour promoter of bladder cancer in rats.
References Hatch, T., et al.: Infect. Immun., 12, 211 (1975); Nishio, Y., et al.: Science, 231, 843 (1986)

Formula: C₂₁D₁₀H₁₃NO₄

Colore e forma: Neat

Peso molecolare: 363.473

Ref: TR-F625027

Fmoc-Ile-OH

CAS: 71989-23-6

Fmoc-Ile-OH is a cyclic peptide that has shown cytotoxic activity against cultured human brain cells. It is also an inhibitor of dipeptidyl peptidase IV (DPP-IV) and inhibits the breakdown of proteins in the brain, such as insulin. Fmoc-Ile-OH binds to the active site of DPP-IV and prevents it from binding to its substrate, thereby inhibiting the enzyme's activity. The inhibition of DPP-IV leads to increased levels of protein in the brain, which may be beneficial for people with Alzheimer's disease. Fmoc-Ile-OH is synthesized on a solid phase by coupling an amino acid with a protected carboxylic acid to yield a protected amide. This product can be used as an encapsulating agent for atosiban, a drug that is used to treat preterm labor.END>>

Formula: C₂₁H₂₃NO₄

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 353.41 g/mol

Ref: 3D-FF15881