CAS 71989-35-0

N-(9-Fluorenilmetossicarbonil)-O-terz-butiltreonina

Descrizione:

N-(9-Fluorenilmetossicarbonil)-O-terz-butiltreonina, comunemente noto come Fmoc-O-t-Bu-Thr, è un derivato di amminoacido protetto ampiamente utilizzato nella sintesi di peptidi. Questo composto presenta un gruppo 9-fluorenilmetossicarbonile (Fmoc), che funge da gruppo protettivo per la funzionalità amminica, consentendo reazioni selettive durante l'assemblaggio dei peptidi. Il gruppo tert-butilico nella catena laterale della treonina fornisce un'ostruzione sterica, migliorando la stabilità della molecola e facilitando i processi di purificazione. Fmoc-O-t-Bu-Thr è tipicamente utilizzato nella sintesi di peptidi in fase solida, dove il gruppo Fmoc può essere facilmente rimosso in condizioni basiche, consentendo il successivo accoppiamento di amminoacidi. Il composto è caratterizzato dalla sua stabilità relativamente alta in condizioni di laboratorio standard, rendendolo adatto per varie applicazioni sintetiche. La sua solubilità in solventi organici e la solubilità moderata in acqua contribuiscono ulteriormente alla sua utilità nella chimica dei peptidi. In generale, Fmoc-O-t-Bu-Thr è un blocco costruttivo essenziale nella sintesi di peptidi, in particolare nel contesto dello sviluppo di agenti terapeutici e strumenti di ricerca in biochimica.

Formula: C₂₃H₂₇NO₅

InChI: InChI=1/C23H27NO5/c1-14(29-23(2,3)4)20(21(25)26)24-22(27)28-13-19-17-11-7-5-9-15(17)16-10-6-8-12-18(16)19/h5-12,14,19-20H,13H2,1-4H3,(H,24,27)(H,25,26)/p-1/t14-,20+/m1/s1

InChI key: InChIKey=LZOLWEQBVPVDPR-VLIAUNLRSA-N

SMILES: C(OC(N[C@@H]([C@H](OC(C)(C)C)C)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Sinonimi:

• (2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid
• (2S,3R)-3-tert-Butoxy-2-[[[[9H-fluoren-9-yl]methoxy]carbonyl]amino)butanoic acid
• (2S,3R)-3-tert-butoxy-2-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}butanoate
• <span class="text-smallcaps">L</span>-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• FMOC-O-tert-Butyl-L-threonine
• Fmoc-L-Thr(tBu)-OH
• Fmoc-Thr(OtBu)-OH
• N-(9-Fluorenylmethoxycarbonyl)-O-tert-butylthreonine
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]threonine
• L-Threonine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-threonine
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-THREONINE
• N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-T-BUTYL-L-THREONINE
• FMOC-L-THR(O-T-BUTYL)
• FMOC-THR(TBU)
• FMOC-THREONINE(TBU)-OH
• FMOC-L-THREONINE (TBU)
• FMOC-L-THREONINE(O-T-BUTYL)
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-THREONINE
• FMOC-O-T-BUTYL-L-THREONINE
• N-(9-FLUORENYL METHOXY CARBONYL)-O-TERT-BUTYL-L-THREONINE
• FMOC-THR(BUT)
• NALPHA-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-THREONINE
• N-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-THRETONINE
• FMOC-THR(TBU)-OH
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-THREONINE
• FMOC-THR(BUT)-OH
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-THEONINE

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

M03389 - Fmoc-Thr(tBu)-OH

Formula: C₂₃H₂₇NO₅

Purezza: 97%

Colore e forma: Crystalline,Powder

Peso molecolare: 397.471

Ref: 10-M03389

Nα-Fmoc-O-tert-butyl-L-threonine, 98%

CAS: 71989-35-0

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₃H₂₇NO₅

Purezza: 98%

Colore e forma: White, Powder

Peso molecolare: 397.47

Ref: 02-H59808

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Bachem ID: 4096755.

Formula: C₂₃H₂₇NO₅

Purezza: 99.9%

Colore e forma: White

Peso molecolare: 397.47

Ref: 01-4096755

(2S,3R)-2-(((9-Fluorenylmethoxy)carbonyl)amino)-3-(tert-butoxy)butanoic acid

CAS: 71989-35-0

Formula: C₂₃H₂₇NO₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 397.4642

Ref: IN-DA0034Y8

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Formula: C₂₃H₂₇NO₅

Purezza: ≥ 98.0%

Colore e forma: White to off-white powder

Peso molecolare: 397.46

Ref: 7W-GM9332

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-threonine

CAS: 71989-35-0

Formula: C₂₃H₂₇NO₅

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 397.47

Ref: 3B-F0505

Fmoc-O-tert-Butyl-L-threonine

CAS: 71989-35-0

Fmoc-O-tert-Butyl-L-threonine

Purezza: 98%

Colore e forma: Powder

Peso molecolare: 397.46g/mol

Ref: 54-OR350183

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fmoc-Thr(tBu)-OH is an ester hydrochloride that is synthesized by reacting the amino acid, Fmoc-Thr(tBu) with trifluoroacetic acid. It has been used to synthesize a cyclic peptide with a protonated amide group, which allows for stereoselective synthesis of the chloride. This product has shown to be resistant to hydrolysis by atosiban and carbonyl oxygens, and also binds to mammalian cell receptors.

Formula: C₂₃H₂₇NO₅

Purezza: Min. 98 Area-%

Colore e forma: White Powder

Peso molecolare: 397.46 g/mol

Ref: 3D-FF15778

Fmoc-Thr(tBu)-OH

CAS: 71989-35-0

Fmoc-Thr(tBu)-OH is an amino acid that is used for the synthesis of amides and esters. It is prepared by the solid-phase synthesis of 2,6-dichloroacetic acid and Fmoc-protected thiomorpholine. The product can be purified by a combination of saponification and trifluoroacetic acid hydrolysis. This amino acid has acidic properties, which may be due to its ability to form ester or amide bonds with other compounds in the presence of a base.

Formula: C₂₃H₂₇NO₅

Purezza: Min. 98.0 Area-%

Peso molecolare: 397.48 g/mol

Ref: 3D-FLT-1700-PI