CAS 71989-38-3

Fmoc-L-Tyr(tBu)-OH

Descrizione:

Fmoc-L-Tyr(tBu)-OH, noto anche come 9-fluorenilmetossicarbonile-L-tirosina (tert-butile), è una forma protetta dell'aminoacido tirosina, comunemente utilizzata nella sintesi di peptidi. Il gruppo Fmoc funge da gruppo protettivo per la funzionalità amminica, consentendo reazioni selettive senza interferire con la catena laterale dell'aminoacido. Il gruppo tert-butile (tBu) protegge il gruppo idrossile della catena laterale della tirosina, migliorando la stabilità e la solubilità del composto durante la sintesi. Questo composto è tipicamente un solido bianco a bianco sporco ed è solubile in solventi organici come il dimetilsolfossido (DMSO) e il diclorometano, ma meno solubile in acqua. La sua struttura molecolare include un anello di fluorene, che contribuisce alla sua stabilità e facilità di rimozione in condizioni dolci durante i passaggi di disattivazione nella sintesi di peptidi. Fmoc-L-Tyr(tBu)-OH è ampiamente utilizzato nel campo della chimica organica e della biochimica per la sintesi di peptidi e proteine, facilitando l'introduzione di residui di tirosina in costruzioni molecolari più grandi.

Formula: C₂₈H₂₉NO₅

InChI: InChI=1/C28H29NO5/c1-28(2,3)34-19-14-12-18(13-15-19)16-25(26(30)31)29-27(32)33-17-24-22-10-6-4-8-20(22)21-9-5-7-11-23(21)24/h4-15,24-25H,16-17H2,1-3H3,(H,29,32)(H,30,31)

InChI key: InChIKey=JAUKCFULLJFBFN-VWLOTQADSA-N

SMILES: C(OC(N[C@@H](CC1=CC=C(OC(C)(C)C)C=C1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Sinonimi:

• (2S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-3-[4-[(2-methylpropan-2-yl)oxy]phenyl]propanoic acid
• (2S)-3-[4-(tert-Butoxy)phenyl]-2-([[(9H-fluoren-9-yl)methoxy]carbonyl]amino)propanoic acid
• (S)-3-(4-tert-Butoxyphenyl)-2-[[[(9H-fluoren-9-yl)methoxy]carbonyl]amino]propionic acid
• <span class="text-smallcaps">L</span>-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-L-Tyr(tBu)-OH
• Fmoc-Tyr(But)-OH
• Fmoc-Tyr(OtBu)-OH
• Fmoc-Tyr(tBu)-OH
• N-(9-Fluorenyl Methoxy Carbonyl)-O-Tertbutyl-L-Tyrosine
• N-alpha-(9-fluorenylmethyloxycarbonyl)-O-t-butyl-L-tyrosine
• N-fmoc-O-T-butyl-L-tyrosine
• NSC 334301
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-tyrosine
• O-tert-butyl-N-[(9H-fluoren-9-ylmethoxy)carbonyl]tyrosine
• Tyr(tBu)
• O-(1,1-Dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-tyrosine
• L-Tyrosine, O-(1,1-dimethylethyl)-N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-O-tert.butyl-L-tyrosine
• FMOC-L-TYR(T-BU)
• N-ALPHA-(9-FLUORENYLMETHYLOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE
• N-(9-FLUORENYLMETHOXYCARBONYL)-O-TERT-BUTYL-L-TYROSINE
• FMOC-L-TYR(O-T-BUTYL)
• FMOC-O-T-BUTYL-L-TYROSINE
• FMOC-TYR(BUT)
• FMOC-TYR(TRT)-OH
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-T-BUTYL-L-TYROSINE
• FMOC-L-TYROSINE(O-T-BUTYL)
• FMOC-L-TYROSINE (TBU)
• FMOC-TYR(TBU)
• N-9-FLUORENYLMETHYLOXYCARBONYL-O-TERT-BUTYL-L-TYROSINE
• FMOC-TYROSINE(TBU)-OH
• 9-FLUORENYLMETHOXYCARBONYL-O-T-BUTYL-L-TYROSINE

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

M03428 - Fmoc-Tyr(tBu)-OH

Formula: C₂₈H₂₉NO₅

Purezza: 98%

Colore e forma: Crystalline Powder,Powder

Peso molecolare: 459.542

Ref: 10-M03428

N-Fmoc-O-tert-butyl-L-tyrosine, 98%

CAS: 71989-38-3

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₂₈H₂₉NO₅

Purezza: 98%

Peso molecolare: 459.54

Ref: 02-H59730

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Bachem ID: 4093144.

Formula: C₂₈H₂₉NO₅

Purezza: 99.8%

Colore e forma: White

Peso molecolare: 459.54

Ref: 01-4093144

Fmoc-O-tert-butyl-L-tyrosine

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 459.5336

Ref: IN-DA0034Y7

Fmoc-L-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-L-Tyr(tBu)-OH

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 459.53g/mol

Ref: 54-BI467

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purezza: ≥ 99.0%

Colore e forma: White to almost white powder

Peso molecolare: 459.53

Ref: 7W-GM6164

Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-tert-butyl-L-tyrosine

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 459.54

Ref: 3B-F0506

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is a protected amino acid for solid-phase peptide synthesis, enabling Leu-EnkephalinAmide formation and versatile amino acid derivatives.

Formula: C₂₈H₂₉NO₅

Purezza: 99.89%

Colore e forma: Solid

Peso molecolare: 459.54

Ref: TM-T67575

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is an amide that binds to the natriuretic receptor. It has a disulfide bond with a hydroxyapatite, which makes it more stable and inhibits its degradation. Fmoc-Tyr(tBu)-OH is hemolytic in vitro and minimally toxic in vivo at high concentrations. It also has a hydroxyl group, which can be used to synthesize other molecules. Fmoc-Tyr(tBu)-OH also has antimicrobial properties, as it inhibits the growth of bacteria and fungi by binding to cell membranes and disrupting their integrity.br>br> Fmoc-Tyr(tBu)-OH is taken up by cells through sodium/hydrogen antiporter system. This uptake process is mediated by the protein Na+, K+ -ATPase, which provides energy for transport across the membrane.

Formula: C₂₈H₂₉NO₅

Purezza: Min. 98 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 459.53 g/mol

Ref: 3D-FF15877

Fmoc-Tyr(tBu)-OH

CAS: 71989-38-3

Fmoc-Tyr(tBu)-OH is a building block for the synthesis of peptides. It is reacted with tert-butyl alcohol and hydrochloric acid to produce the corresponding Fmoc-protected tyrosine. The Fmoc group can be removed by treatment with dicyclohexylcarbodiimide and tert-butyl alcohol, followed by saponification in aqueous base. The morphologies of the resulting free amino acids are determined by their solubility in organic solvents such as chloroform or ethyl acetate, as well as in water.

Formula: C₂₈H₂₉NO₅

Purezza: Min. 98.0 Area-%

Peso molecolare: 459.53 g/mol

Ref: 3D-FLY-1737-PI

FMOC-O-Tert-Butyl-L-Tyrosine (FMOC-Tyr(tBu)-OH) extrapure, 98%

CAS: 71989-38-3

Formula: C₂₈H₂₉NO₅

Purezza: min. 98%

Colore e forma: White, Crystalline powder

Peso molecolare: 459.53

Ref: SR-22292

Fmoc-L-Tyr(tBu)-OH

Prodotto controllato

CAS: 71989-38-3

Applications Fmoc-L-Tyr(tBu)-OH is tyrosine derivative used in soiid phase peptide synthesis.
References Atherton, E., et al.: J. Chem. Soc. Chem. Comm., 20, 970 (1980);

Formula: C₂₈H₂₉NO₅

Colore e forma: Neat

Peso molecolare: 459.53

Ref: TR-F622860