CAS 72558-82-8

Ceftazidima

Descrizione:

Ceftazidima è un antibiotico cefalosporinico di terza generazione, utilizzato principalmente per trattare infezioni causate da batteri Gram-negativi, inclusa Pseudomonas aeruginosa. È caratterizzato dalla sua attività ad ampio spettro, rendendolo efficace contro una varietà di patogeni. La struttura chimica di Ceftazidima include un anello beta-lattamico, essenziale per la sua attività antibatterica, e una catena laterale che ne migliora la stabilità contro alcune beta-lattamasi. Ceftazidima viene tipicamente somministrato per iniezione ed è noto per il suo profilo di tossicità relativamente basso. Viene spesso utilizzato in contesti ospedalieri per infezioni gravi, tra cui polmonite, infezioni del tratto urinario e sepsi. Il farmaco è generalmente ben tollerato, sebbene gli effetti collaterali potenziali possano includere reazioni allergiche, disturbi gastrointestinali e alterazioni nella coagulazione del sangue. La sua farmacocinetica prevede l'escrezione renale, richiedendo aggiustamenti della dose nei pazienti con funzione renale compromessa. Nel complesso, Ceftazidima rimane un'opzione critica nell'arsenale degli antibiotici, particolarmente per il trattamento di infezioni batteriche resistenti.

Formula: C₂₂H₂₂N₆O₇S₂

InChI: InChI=1S/C22H22N6O7S2/c1-22(2,20(33)34)35-26-13(12-10-37-21(23)24-12)16(29)25-14-17(30)28-15(19(31)32)11(9-36-18(14)28)8-27-6-4-3-5-7-27/h3-7,10,14,18H,8-9H2,1-2H3,(H4-,23,24,25,29,31,32,33,34)/t14-,18-/m1/s1

InChI key: InChIKey=ORFOPKXBNMVMKC-DWVKKRMSSA-N

SMILES: C([O-])(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC(C(O)=O)(C)C)/C3=CSC(N)=N3)=O)C2=O)(SCC1C[N+]=4C=CC=CC4)[H]

Sinonimi:

• (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl}amino)-8-oxo-3-(pyridinium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate pentahydrate
• (6R,7R)-7-[(3Z)-3-(2-aminothiazol-4-yl)-3-(2-hydroxy-1,1-dimethyl-2-oxo-ethoxy)imino-2-oxo-propyl]-8-oxo-3-(pyridin-1-ium-1-ylmethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• (6R,7R)-7-[(Z)-2-(Aminothiazol-4-yl)-2-(2-carboxypropoxyimino)acetamido]-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate
• 1-(((6R,7R)-7-(((2Z)-(2-Amino-4-Thiazolyl)((1-Carboxy-1-Methylethoxy)Imino) Acetyl) Amino)-2-Carboxy-8-Oxo-5-Thia-1-Azabicyclo(4.2.0) Oct-2-En-3-Yl)Methyl)Pyridinum Hydroxide Inner Salt
• Biotum
• Cefazid
• Ceftacidin
• Ceftazidim
• Ceftazidima
• Ceftazidime anhydrous
• Ceftazidine
• Fortam
• Fortaz
• Fortum
• Gr 20263
• Modacin
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
• Pyridinium, 1-[[(6R,7R)-7-[[(2Z)-2-(2-amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, inner salt
• Pyridinium, 1-[[7-[[(2-amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-, hydroxide, inner salt, [6R-[6α,7β(Z)]]-
• Solvetan
• Tazicef
• Tazid
• Tazidime
• Tizime
• Zidim
• Ceftazidime
• pyridinium,1-((7-(((2-amino-4-thiazolyl)((1-carboxy-1-methylethoxy)imino)acety
• Kefadim
• Kefamin
• (6R,7R)-7-[2-(2-Amino-4-thiazolyl)-2-[(Z)-1-carboxy-1-methylethoxyimino]acetylamino]-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]octan-2-ene-2-carboxylate
• Stareef
• Tazicef：CAZ
• Panzid
• (6R,7R)-7-[[(Z)-(2-Amino-4-thiazolyl)[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-8-oxo-3-(pyridiniomethyl)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
• innersalt,(6r-(6-alpha,7-beta-(z)))-droxid
• gr20263
• C06889
• 1-[[(6R,7R)-7-[[(2Z)-2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]pyridinium Inner Salt
• Glazidim
• Ceftazidime/Sodium Carbonate
• CeftazidiMe with SodiuM Carbonate
• CeftazidiMe (C22H22N6O7S2 · xH2O)
• hy
• 72558-82-8
• Ceftim，Fortam
• thermogra
• CEFTAZIDIME HYDRATE
• [(6R-[6α，7β(Z)]]-1-[[7-[[(2-Amino-4-thiazolyl)[(1-earboxy-1-methylethoxy)imino]acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabieyelo[4.2.0]oct-2-en-3-y1]methyl]pyridinium inner salt
• sn401
• Ceptaz
• Ceftazidime (contains ca. 10% Na2CO3)
• caz

Ceftazidime (contains ca. 10% Na2CO3)

CAS: 72558-82-8

Formula: C₂₂H₂₂N₆O₇S₂

Purezza: min. 98.0 area%(HPLC)

Colore e forma: White to Orange to Green powder to crystal

Peso molecolare: 546.57

Ref: 3B-C2225

Ceftazidime

CAS: 72558-82-8

Ceftazidime (GR20263) is a beta-lactam, cephalosporin antibiotic with bactericidal activity.

Formula: C₂₂H₂₂N₆O₇S₂

Purezza: 99.1% - 99.85%

Colore e forma: Solid

Peso molecolare: 546.58

Ref: TM-T1305

Ceftazidime

CAS: 72558-82-8

Formula: C₂₂H₂₂N₆O₇S₂

Peso molecolare: 546.57

Ref: 4Z-C-10508

Ceftazidime

CAS: 72558-82-8

Ceftazidime

Purezza: ≥98%

Peso molecolare: 546.58g/mol

Ref: 54-BUP18065

Ceftazidime-d5

CAS: 72558-82-8

Formula: C₂₂H₁₇D₅N₆O₇S₂

Peso molecolare: 551.60

Ref: 4Z-C-10511

Ceftazidime, Antibiotic for Culture Media Use Only

CAS: 72558-82-8

Ceftazidime is a fine chemical that can be used as a versatile building block for complex compounds. It is a useful reagent and research chemical. Ceftazidime is an important intermediate in the synthesis of other compounds and has been used as a reaction component to produce useful scaffolds. Ceftazidime has CAS No. 72558-82-8, making it a speciality chemical with high quality.

Formula: C₂₂H₂₂N₆O₇S₂

Purezza: Min. 95.0 Area-%

Peso molecolare: 546.57 g/mol

Ref: 3D-C-2510

Ceftazidime - Bio-X ™

CAS: 72558-82-8

Ceftazidime is a broad-spectrum beta-lactam antibiotic that inhibits bacterial growth by inhibiting penicillin-binding proteins (PBPs). It is used to treat many bacteria infections including pneumonia and septicaemia. It has shown to be effective against some treatment-resistant bacteria such as Pseudomonas aeruginosa.

Formula: C₂₂H₂₂N₆O₇S₂

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 546.58 g/mol

Ref: 3D-BC300021

Ceftazidime

CAS: 72558-82-8

Ceftazidime is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating severe bacterial infections like pneumonia, meningitis, and sepsis.

Formula: C₂₂H₂₂N₆O₇S₂

Purezza: Min. 95.0 Area-%

Colore e forma: Powder

Peso molecolare: 546.58 g/mol

Ref: 3D-FA153265