CAS 72956-09-3

Carvedilol

Descrizione:

Carvedilol è un antagonista beta-adrenergico non selettivo e un bloccante alfa-1, utilizzato principalmente nella gestione dell'ipertensione e dell'insufficienza cardiaca. La sua formula chimica è C24H26N2O4 e presenta una struttura complessa che include un gruppo fenolico e un centro chirale, che contribuisce alla sua attività farmacologica. Carvedilol mostra proprietà antiossidanti e ha dimostrato di migliorare la funzione del ventricolo sinistro nei pazienti con insufficienza cardiaca. Agisce bloccando gli effetti dell'adrenalina sul cuore e sui vasi sanguigni, portando a una diminuzione della frequenza cardiaca e della pressione sanguigna. La sostanza è tipicamente somministrata per via orale ed è ben assorbita, con una biodisponibilità che può essere influenzata dall'assunzione di cibo. Carvedilol è generalmente ben tollerato, ma gli effetti collaterali potenziali possono includere vertigini, affaticamento e ipotensione. I suoi effetti terapeutici sono attribuiti alla sua capacità di ridurre il carico cardiaco e migliorare la emodinamica, rendendolo un farmaco prezioso nella terapia cardiovascolare.

Formula: C₂₄H₂₆N₂O₄

InChI: InChI=1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3

InChI key: InChIKey=OGHNVEJMJSYVRP-UHFFFAOYSA-N

SMILES: O(CC(CNCCOC1=C(OC)C=CC=C1)O)C2=C3C=4C(NC3=CC=C2)=CC=CC4

Sinonimi:

• (.+-.)-Carvedilol
• 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
• 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]propan-2-ol
• Artist
• Bm 14190
• Cadilan
• Carca
• Cardivas
• Carloc
• Carvas
• Carvediol
• Carvexal
• Carvil
• Coreg
• Coronis
• Dilatrend
• Dimitone
• Dq 2466
• Eucardic
• Korvasan
• Kredex
• Querto
• Skf 105517
• Talliton
• Carvedilo
• CarvedilolEp5
• caredilol
• CarvedilolEdmf/Gmp
• 2-Propanol, 1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-
• 1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol 2,3-dihydroxybutanedioate (salt)
• Carvediloledmf/Gmpep5
• CarvedilolC24H26N204
• 1-(9h-carbozol-4-yloxy)-3-[[2-(2-methoxy phenoxy)ethyl] amino]-2-propanol

Carvedilol

CAS: 72956-09-3

Formula: C₂₄H₂₆N₂O₄

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Almost white powder to crystal

Peso molecolare: 406.48

Ref: 3B-C2260

Carvedilol

CAS: 72956-09-3

Colore e forma: Neat

Ref: 61-FOR0291.00

Carvedilol 1.0 mg/ml in Methanol

CAS: 72956-09-3

Colore e forma: Single Solution

Ref: 61-AMP0291.00-01

Carvedilol

CAS: 72956-09-3

Carvedilol

Formula: C₂₄H₂₆N₂O₄

Purezza: 99.8%

Colore e forma: White

Peso molecolare: 406.18926

Ref: 47-1168

CARVEDILOL CRS

CAS: 72956-09-3

CARVEDILOL CRS

Formula: C₂₄H₂₆N₂O₄

Colore e forma: Added Modified

Peso molecolare: 406.4742

Ref: 41-Y0001427

CARVEDILOL FOR SYSTEM SUITABILITY CRS

CAS: 72956-09-3

CARVEDILOL FOR SYSTEM SUITABILITY CRS

Formula: C₂₄H₂₆N₂O₄

Colore e forma: Added Modified

Peso molecolare: 406.4742

Ref: 41-Y0001426

Carvedilol

CAS: 72956-09-3

Cardiovascular drugs, nesoi

Formula: C₂₄H₂₆N₂O₄

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 406.18926

Ref: 45-1096622

Carvedilol

CAS: 72956-09-3

Carvedilol (SKF 105517) Phosphate is the phosphate salt form of carvedilol, a racemic mixture and adrenergic blocking agent with antihypertensive activity and devoid of intrinsic sympathomimetic activity. The S enantiomer of carvedilol nonselectively binds to and blocks beta-adrenergic receptors, thereby exerting negative inotropic and chronotropic effects, and leading to a reduction in cardiac output. In addition, both enantiomers of carvedilol bind to and block alpha 1-adrenergic receptors, thereby causing vasodilation and reducing peripheral vascular resistance.

Formula: C₂₄H₂₆N₂O₄

Purezza: 99.73% - 99.97%

Colore e forma: Colourless Crystalline Powder

Peso molecolare: 406.47

Ref: TM-T0447

Carvedilol

CAS: 72956-09-3

Formula: C₂₄H₂₆N₂O₄

Purezza: ≥ 98.0% (dried basis)

Colore e forma: White or almost white crystalline powder

Peso molecolare: 406.47

Ref: 7W-GP1095

Carvedilol, EP grade

CAS: 72956-09-3

Formula: C₂₄H₂₆N₂O₄

Peso molecolare: 406.47

Ref: 7W-GP3984

Carvedilol

CAS: 72956-09-3

Formula: C₂₄H₂₆N₂O₄

Colore e forma: White To Off-White Solid

Peso molecolare: 406.48

Ref: 4Z-C-021

Carvedilol

CAS: 72956-09-3

Colore e forma: Neat

Ref: 86-MM0291.00

Carvedilol

Prodotto controllato

CAS: 72956-09-3

Applications Carvedilol is a nonselective β-adrenergic blocker with α1-blocking activity. Carvedilol is an antihypertensive used in the treatment of congestive heart failure.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Hirohashi, M., et al.: Arzneim.-Forsch., 40, 735 (1990); Packer, M., et al.: N. Engl. J. Med., 334, 1349 (1996);

Formula: C₂₄H₂₆N₂O₄

Colore e forma: White

Peso molecolare: 406.47

Ref: TR-C184625

Carvedilol - Bio-X ™

Prodotto controllato

CAS: 72956-09-3

Carvediol is a nonselective beta-adrenoceptor blocking agent and an alpha 1-adrenoceptor blocker. It can be used as a drug, belonging to the class of beta blockers, in the treatment of heart failure, coronary artery disease, and hypertension. Carvedilol has been shown to reduce the risk of death in patients with heart failure and improve symptoms. Furthermore it has an effect on blood pressure by decreasing peripheral vascular resistance and mean arterial pressure. Carvedilol can be metabolized by cytochrome P450 enzymes and CYP2D6 and CYP2C9 liver enzymes.

Formula: C₂₄H₂₆N₂O₄

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 406.47 g/mol

Ref: 3D-BC164291

Carvedilol

Prodotto controllato

CAS: 72956-09-3

Carvediol is a nonselective beta-adrenoceptor blocking agent and an alpha 1-adrenoceptor blocker. It can be used as a drug, belonging to the class of beta blockers, in the treatment of heart failure, coronary artery disease, and hypertension. Carvedilol has been shown to reduce the risk of death in patients with heart failure and improve symptoms. Furthermore it has an effect on blood pressure by decreasing peripheral vascular resistance and mean arterial pressure. Carvedilol can be metabolized by cytochrome P450 enzymes and CYP2D6 and CYP2C9 liver enzymes.

Formula: C₂₄H₂₆N₂O₄

Purezza: Min. 98.5 Area-%

Colore e forma: White Off-White Powder

Peso molecolare: 406.47 g/mol

Ref: 3D-FC11729

Carvedilol-13C6

Prodotto controllato

CAS: 72956-09-3

Formula: C₆C₁₈H₂₆N₂O₄

Colore e forma: Neat

Peso molecolare: 412.43

Ref: TR-C184629

Carvedilol-13C3

Prodotto controllato

CAS: 72956-09-3

Formula: C₃C₂₁H₂₆N₂O₄

Colore e forma: Neat

Peso molecolare: 409.452

Ref: TR-C154800

1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol

CAS: 72956-09-3

Formula: C₂₄H₂₆N₂O₄

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 406.4742

Ref: IN-DA0036JK