CAS 74103-06-3

Ketorolac

Descrizione:

Ketorolac è un farmaco antinfiammatorio non steroideo (FANS) utilizzato principalmente per le sue proprietà analgesiche, in particolare nella gestione del dolore da moderato a severo. È caratterizzato dalla sua capacità di inibire l'enzima cicloossigenasi (COX), che svolge un ruolo cruciale nella sintesi delle prostaglandine, composti coinvolti nell'infiammazione e nella segnalazione del dolore. Ketorolac viene spesso somministrato per via orale, intramuscolare o endovenosa, ed è noto per il suo rapido inizio d'azione. La sostanza è tipicamente utilizzata in contesti post-operatori o per il sollievo del dolore acuto, ma il suo uso è generalmente limitato a trattamenti a breve termine a causa dei potenziali effetti collaterali, tra cui sanguinamento gastrointestinale, compromissione renale e rischi cardiovascolari. Ketorolac è anche notevole per la sua potenza relativamente alta rispetto ad altri FANS, rendendolo efficace a dosi più basse. Come con tutti i farmaci, è essenziale utilizzare Ketorolac sotto supervisione medica per mitigare i rischi e monitorare gli effetti avversi.

Formula: C₁₅H₁₃NO₃

InChI: InChI=1S/C15H13NO3/c17-14(10-4-2-1-3-5-10)13-7-6-12-11(15(18)19)8-9-16(12)13/h1-7,11H,8-9H2,(H,18,19)

InChI key: InChIKey=OZWKMVRBQXNZKK-UHFFFAOYSA-N

SMILES: C(=O)(C=1N2C(C(C(O)=O)CC2)=CC1)C3=CC=CC=C3

Sinonimi:

• 1H-pyrrolizine-1-carboxylic acid, 5-benzoyl-2,3-dihydro-
• 5-(phenylcarbonyl)-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
• 5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid
• Aagn 199584
• Acular LS
• Keromin
• Rs 37619
• Sprix
• Sukerin
• acide 5-benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylique
• Ketorolac

Ketorolac

CAS: 74103-06-3

Formula: C₁₅H₁₃NO₃

Colore e forma: Off-White Solid

Peso molecolare: 255.28

Ref: 4Z-K-0313

Ketorolac

CAS: 74103-06-3

Ketorolac

Purezza: ≥98%

Peso molecolare: 255.27g/mol

Ref: 54-BUP17317

Ketorolac

Prodotto controllato

CAS: 74103-06-3

Formula: C₁₅H₁₃NO₃

Colore e forma: Off White Solid

Peso molecolare: 255.27

Ref: 04-C14533000

Ketorolac Tromethamine

CAS: 74103-06-3, 74103-07-4

Formula: C₁₅H₁₃NO₃·C₄H₁₁NO₃

Purezza: >98.0%(T)(HPLC)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 376.41

Ref: 3B-K0053

Ketorolac

CAS: 74103-06-3

Ketorolac (Acuvail) is an NSAID that blocks prostaglandin synthesis, related to heterocyclic acetic acids.

Formula: C₁₅H₁₃NO₃

Purezza: 99.68%

Colore e forma: White Crystalline Or White Powder

Peso molecolare: 255.27

Ref: TM-T21412

5-Benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic acid

CAS: 74103-06-3

5-Benzoyl-2,3-dihydro-1h-pyrrolizine-1-carboxylic acid

Formula: C₁₅H₁₃NO₃

Purezza: 95%

Colore e forma: light yellow powder

Peso molecolare: 255.27g/mol

Ref: 54-OR345134

rac Ketorolac

Prodotto controllato

CAS: 74103-06-3

Applications Ketorolac is an analgesic; anti-inflammatory.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Etman, M., et al.: Pharm. Technol., 32, 58 (2008), Chelladurai, S., et al.: Chem. Pharm. Bull., 56, 1596 (2008), Sanderson, H., et al.: Toxicol. Lett., 187, 84 (2009),

Formula: C₁₅H₁₃NO₃

Colore e forma: Off White Solid

Peso molecolare: 255.27

Ref: TR-K235615

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid

CAS: 74103-06-3

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 255.2729949951172

Ref: 10-F242512

Ketorolac

CAS: 74103-06-3

Ketorolac is a nonsteroidal anti-inflammatory drug that acts by inhibiting the synthesis of prostaglandins. It is used to control moderate to severe pain, and for reducing postoperative, postpartum and other types of pain. Ketorolac has been shown to be effective in a variety of clinical settings, including those involving hepatic impairment and congestive heart failure. The drug has minimal toxicity and can be used at high doses without adverse effects on the liver or kidney. In addition, ketorolac does not produce significant changes in pge2 levels in experimental models or human serum when administered orally.

Formula: C₁₅H₁₃NO₃

Purezza: Min. 98 Area-%

Colore e forma: Powder

Peso molecolare: 255.27 g/mol

Ref: 3D-FK35139

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic

CAS: 74103-06-3

5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid - Racemic (5BPC) is a drug that is used for the treatment of pain. It has been shown to be safe and effective in treating postoperative pain when given by intravenous infusion or as an oral tablet. 5BPC has minimal toxicity and is metabolized primarily by the liver with a half life of 2.6 hours. The drug has been found to have pharmacokinetic properties that allow it to be used safely in patients with hepatic impairment and in those recovering from abdominal surgery. 5BPC is a prodrug that undergoes biotransformation by esterases into its active form, pyrrolizidine alkaloid (PA). PA acts as a nonsteroidal anti-inflammatory agent and inhibits prostaglandin synthesis, which leads to analgesia. This drug also has minimal drug interactions because

Formula: C₁₅H₁₃O₃N

Purezza: Min. 95%

Peso molecolare: 255.27 g/mol

Ref: 3D-IB58062