CAS 74397-12-9
:Limaprost
Descrizione:
Limaprost è un analogo sintetico delle prostaglandine utilizzato principalmente per i suoi effetti vasodilatatori, in particolare nel trattamento delle malattie vascolari periferiche e delle condizioni associate a un flusso sanguigno compromesso. È caratterizzato dalla sua capacità di migliorare la circolazione sanguigna rilassando il muscolo liscio vascolare, il che può portare a una migliore fornitura di ossigeno ai tessuti. Limaprost viene spesso somministrato sotto forma di compresse orali o iniezioni, a seconda dell'indicazione clinica. La sostanza presenta un'emivita relativamente breve, richiedendo un dosaggio attento per mantenere livelli terapeutici. Il suo meccanismo d'azione coinvolge l'attivazione di specifici recettori delle prostaglandine, che mediano varie risposte fisiologiche, inclusa l'inibizione dell'aggregazione piastrinica e la modulazione dei processi infiammatori. Inoltre, Limaprost può avere effetti collaterali come mal di testa, arrossamento o disturbi gastrointestinali, che devono essere monitorati durante il trattamento. Come per qualsiasi farmaco, il suo utilizzo deve essere guidato da un professionista sanitario, considerando lo stato di salute generale del paziente e le potenziali interazioni farmacologiche.
Formula:C22H36O5
InChI:InChI=1/C22H36O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h8,11-13,16-19,21,23,25H,3-7,9-10,14-15H2,1-2H3,(H,26,27)/b11-8+,13-12+/t16-,17+,18+,19+,21+/m0/s1
InChI key:InChIKey=OJZYRQPMEIEQFC-UAWLTFRCSA-N
SMILES:C(CCC/C=C/C(O)=O)[C@@H]1[C@@H](/C=C/[C@H](C[C@H](CCCC)C)O)[C@H](O)CC1=O
Sinonimi:- (2E)-7-[(1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-2-heptenoic acid
- (2E)-7-{(1R,2R,3R)-3-Hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl}-2-heptenoic acid (non-preferred name)
- (E)-7-((1R,2R,3R)-3-Hydroxy-2-((E)-(3S,5S)-3-hydroxy-5-methyl-1-nonenyl)-5-oxocyclopentyl)-2-heptenoic acid
- (E)-7-((1R,2R,3R)-3-Hydroxy-2-((E)-(3S,5S)-3-hydroxy-5-methyl-1-nonenyl)-5-oxocyclopentyl)-2-heptenoic acid 17S-Methyl-w-homo-trans-D2-PGE1
- 17S,20-Dimethyl-trans-D2-PGE1
- 17S,20-Dimethyl-trans-Δ<sup>2</sup>-PGE<sub>1</sub>
- 17S-Methyl-w-homo-trans-D2-PGE1
- 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonen-1-yl]-5-oxocyclopentyl]-, (2E)-
- 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-, (2E)-
- 2-Heptenoicacid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-,(2E)-
- 2E,11a,13E,15S,17S)-11,15-Dihydroxy-17,20-dimethyl-9-oxoprosta-2,13-dien-1-oic Acid
- 9-Oxo-11a,15a-dihydroxy-17S,20-dimethylprosta-trans-2,trans-13-dienoic Acid
- Limaprost
- Ono 1206
- Op 1206
- Op1206
- Prosta-2,13-dien-1-oic acid,11,15-dihydroxy-17,20-dimethyl-9-oxo-, (2E,11a,13E,15S,17S)-
- 17α,20-dimethyl-δ2-PGE1
- n-1-oicacid
- 11ALPHA, 15S-DIHYDROXY-17S,20-DIMETHYL-9-OXO-PROSTA-2E, 13E-DIEN-1-OIC ACID
- D02722
- ,13e,15s,17s)-
- 17A,20-DIMETHYL-D2-PGE1
- 9-oxo-11-alpha,15-alpha-dihydroxy-17s,20-dimethylprosta-trans-2,trans-13-die
- (2E,11R,13E,15S,17S)-11α,15-Dihydroxy-17,20-dimethyl-9-oxoprosta-2,13-dien-1-oic acid
- 11A,15S-DIHYDROXY-17S,20-DIMETHYL-9-OXO-PROSTA-2E,13E-DIEN-1-OIC ACID
- ono1206
- (2e,11-alpha,13e,15s,17s)-11,15-dihydroxy-17,20-dimethyl-9-oxoprost-2,13-die
- 17α,20-dimethyl-δ2-PGE1, 11α,15S-Dihydroxy-17S,20-dimethyl-9-oxo-prosta-2E,13E-dien-1-oic acid
- (2E)-7-[(1R)-2β-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonenyl]-3α-hydroxy-5-oxocyclopentan-1α-yl]-2-heptenoic acid
- 2-Heptenoic acid, 7-[(1R,2R,3R)-3-hydroxy-2-[(1E,3S,5S)-3-hydroxy-5-methyl-1-nonenyl]-5-oxocyclopentyl]-, (2E)-(9CI)
- 17s,20-dimethyl-trans-2,3-didehydro-pge1
- prost-2,13-dien-1-oicacid,11,15-dihydroxy-17,20-dimethyl-9-oxo-,(2e,11-alpha
- 11α,15s-dihydroxy-17s,20-dimethyl-9-oxo-prosta-2e,13e-dien-1-oic acid
- Vedi altri sinonimi
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9 prodotti.
Limaprost
CAS:Formula:C22H36O5Purezza:≥ 99.0%Colore e forma:White to off-white powderPeso molecolare:380.52Ref: 4Z-L-099001
5mgPrezzo su richiesta10mg1.214,00€25mg2.184,00€50mg3.398,00€100mgPrezzo su richiestaLimaprost
CAS:Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is aFormula:C22H36O5Purezza:99.61% - 99.89%Colore e forma:SolidPeso molecolare:380.52Limaprost
CAS:Prodotto controllato<p>Stability Hygroscopic<br>Applications Limaprost is an analog of Prostaglandin E1 with structural modifications intended to give it a prolonged half-life and greater potency. Limaprost is used as an antianginal.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Tsuboi, T., et al.: Arch. Int. Pharmacodyn., 247, 89 (1980), Adaikan, P.G., et al.: Prostaglandins Med., 6, 449 (1981), Kottegoda, S.R., et al.: Prostaglandins Leukotrienes Med., 8, 343 (1982), Ishizaki, T., et al.: Chest, 85, 382 (1984),<br></p>Formula:C22H36O5Colore e forma:NeatPeso molecolare:380.52Limaprost
CAS:<p>Limaprost is a nonsteroidal anti-inflammatory drug (NSAID) that belongs to the group of coumarin derivatives. It is used in the treatment of diabetic neuropathy, and has also been shown to reduce blood levels of cholesterol. Limaprost can be administered orally or topically, and blocks prostaglandin synthesis by inhibiting cyclooxygenase. Limaprost is available as a tablet and injection for oral use. The drug is also used for relief of pain in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and other musculoskeletal disorders. Limaprost is metabolized by esterases in the liver to form desacetyllimaprost (DALP), which has approximately one-third the potency of limaprost. DALP's metabolites are excreted primarily through bile into the intestine, where they are reabsorbed back into the bloodstream. They are then</p>Formula:C22H36O5Purezza:Min. 95%Colore e forma:PowderPeso molecolare:380.52 g/mol
