CAS 747-36-4

Solfato di idrossiclorochina

Descrizione:

Solfato di idrossiclorochina è un farmaco antimalarico e immunomodulatore utilizzato principalmente per trattare la malaria, l'artrite reumatoide e il lupus eritematoso. È un derivato della clorochina e funziona interferendo con la crescita dei parassiti nei globuli rossi. Il composto è caratterizzato dalla sua capacità di inibire l'attività lisosomiale all'interno delle cellule, fondamentale per la sopravvivenza di alcuni patogeni. Solfato di idrossiclorochina viene tipicamente somministrato per via orale ed è noto per il suo profilo di tossicità relativamente basso rispetto ad altri antimalarici. La sua struttura chimica include un gruppo 4-aminochinolina, essenziale per la sua attività farmacologica. La forma di sale solfato ne migliora la solubilità e stabilità. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, reazioni cutanee e, in rari casi, tossicità retinica con uso prolungato. A causa dei suoi effetti immunomodulatori, l'idrossiclorochina ha attirato l'attenzione in vari usi off-label, in particolare nelle malattie autoimmuni. Tuttavia, la sua efficacia e sicurezza in questi contesti continuano a essere oggetto di ricerca e valutazione clinica in corso.

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

InChI: InChI=1S/C18H26ClN3O.H2O4S/c1-3-22(11-12-23)10-4-5-14(2)21-17-8-9-20-18-13-15(19)6-7-16(17)18;1-5(2,3)4/h6-9,13-14,23H,3-5,10-12H2,1-2H3,(H,20,21);(H2,1,2,3,4)

InChI key: InChIKey=JCBIVZZPXRZKTI-UHFFFAOYSA-N

SMILES: S(=O)(=O)(O)O.N(C(CCCN(CCO)CC)C)C=1C2=C(N=CC1)C=C(Cl)C=C2

Sinonimi:

• 2-((4-((7-Chloro-4-quinolyl)amino)pentyl)ethylamino)ethanol sulfate
• 2-([4-[(7-Chloroquinolin-4-yl)amino]pentyl](ethyl)amino)ethan-1-ol; sulfuric acid
• 7-Chloro-4-[4-N-ethyl-N-beta-hydroxyethylamino-1-methylbutylamino]quinoline sulfate
• 7-Chloro-4-[4-[ethyl(2-hydroxyethyl)amino]-1-methylbutylamino]-quinoline sulfate
• 7-chloro-4-({(1R)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• 7-chloro-4-({(1S)-4-[ethyl(2-hydroxyethyl)ammonio]-1-methylbutyl}amino)quinolinium
• Ercoquin
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1)
• Ethanol, 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Ethanol, 2-[[4-[(7-chloro-4-quinolyl)amino]pentyl]ethylamino]-, sulfate (1:1) (salt)
• Hydrochloroquine Sulfate
• Hydroxy chloroquine sulfate
• Hydroxychloroquine sulfate
• NSC 4375
• Plaquenil
• Plaquenil sulfate
• Quensyl

Hydroxychloroquine Sulfate

CAS: 118-42-3, 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purezza: >98.0%(HPLC)(N)

Colore e forma: White to Light yellow powder to crystal

Peso molecolare: 433.95

Ref: 3B-H1306

HYDROXYCHLOROQUINE SULFATE CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE SULFATE CRS

Formula: C₁₈H₂₈ClN₃O₅S

Colore e forma: Modified

Peso molecolare: 433.95

Ref: 41-Y0001839

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

CAS: 747-36-4

HYDROXYCHLOROQUINE FOR SYSTEM SUITABILITY CRS

Formula: C₁₈H₂₈ClN₃O₅S

Colore e forma: White. Whitish. Crystalline Powder.

Peso molecolare: 433.95

Ref: 41-Y0001841

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Formula: C₁₈H₂₆CIN₃OH₂SO₄

Purezza: 99.7%

Colore e forma: White. To. Off-White

Peso molecolare: 537.07944

Ref: 47-1100

Hydroxychloroquine Sulfate

CAS: 747-36-4

Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fused

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

Colore e forma: White Off-White Crystalline Powder

Peso molecolare: 433.14382

Ref: 45-1327000

Hydroxychloroquine sulfate

CAS: 747-36-4

Formula: C₁₈H₂₈ClN₃O₅S

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 433.9500

Ref: IN-DA0059P3

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase.

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purezza: 98.92% - 99.88%

Colore e forma: White Solid

Peso molecolare: 433.95

Ref: TM-T0951

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purezza: ≥98%

Peso molecolare: 433.95

Ref: 54-BUP16035

Hydroxychloroquine sulfate

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purezza: ≥ 98.0%

Colore e forma: White to off-white crystalline powder

Peso molecolare: 433.95

Ref: 7W-GK2606

Hydroxychloroquine Sulfate

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

Colore e forma: White To Off-White Solid

Peso molecolare: 335.88 98.07

Ref: 4Z-H-061

Hydroxychloroquine Sulphate 1.0 mg/ml in Methanol (as free base)

CAS: 747-36-4

Colore e forma: Single Solution

Ref: 61-AMP0764.00-01

Hydroxychloroquine Sulphate

CAS: 747-36-4

Colore e forma: Neat

Ref: 86-MM0764.00

Hydroxychloroquine sulfate (Standard)

CAS: 747-36-4

Hydroxychloroquine sulfate (Standard) is a reference standard for research and analysis in studies involving Hydroxychloroquine sulfate. Hydroxychloroquine sulfate (Acidum iopanoicum) inhibits plasmodial heme polymerase. It is a chemotherapeutic agent that acts against erythrocytic forms of malarial parasites. Hydroxychloroquine appears to concentrate in food vacuoles of affected protozoa.

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Peso molecolare: 433.95

Ref: TM-TMSM-3523

Hydroxychloroquine Sulphate

CAS: 747-36-4

Colore e forma: Neat

Ref: 61-FOR0764.00

Hydroxychloroquine sulfate

CAS: 747-36-4

2-((4-((7-Chloroquinolin-4-yl)amino)pentyl)(ethyl)amino)ethanol sulfate

Formula: C₁₈H₂₈ClN₃O₅S

Purezza: 99%

Peso molecolare: 433.95

Ref: IN-DG134190

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine sulfate

Formula: C₁₈H₂₆ClN₃O·H₂SO₄

Purezza: 99%

Colore e forma: Solid

Peso molecolare: 433.95002

Ref: 54-BISN0145

Hydroxychloroquine Sulfate

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃OH₂SO₄

Peso molecolare: 335.9 : 98.1

Ref: ST-EA-CP-H4012

Hydroxychloroquine Sulfate

Prodotto controllato

CAS: 747-36-4

Formula: C₁₈H₂₆ClN₃O·H₂O₄S

Colore e forma: Neat

Peso molecolare: 433.95

Ref: TR-H916900

Hydroxychloroquine sulfate - Bio-X ™

CAS: 747-36-4

Hydroxychloroquine is a drug that is used to treat multiple types of autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus and discoid lupus. It is a prodrug, which is activated in the liver to hydroxychloroquine. It inhibits the production of inflammatory cytokines and nitric oxide by binding to the toll-like receptor 4 (TLR4) and inhibiting signaling pathways downstream of TLR4 activation. Additionally, Hydroxychloroquine is used to prevent and treat malaria caused by parasitic protozoan from the Plasmodium genus. Furthermore, recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Formula: C₁₈H₂₈ClN₃O₅S

Purezza: Min. 95%

Colore e forma: Powder

Peso molecolare: 433.95 g/mol

Ref: 3D-BH164525

Hydroxychloroquine sulfate

CAS: 747-36-4

Hydroxychloroquine is a 4-aminoquinolone that is used to prevent and treat malaria, caused by parasitic protozoan from the Plasmodium genus. Hydroxychloroquine is also used to treat non-infectious diseases such as rheumatoid arthritis and lupus thanks to its immunomodulatory properties. Recent studies revealed that hydroxychloroquine has beneficial effects on COVID-19 patients, as the current evidence shows that hydroxychloroquine inhibits SARS CoV-2 entry in host cells by interfering with endocytosis and affecting the glycoprofile on the spike glycoprotein.

Formula: C₁₈H₂₆ClN₃O•H₂SO₄

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 433.95 g/mol

Ref: 3D-FH24322