CAS 74853-08-0

4-[4-(4-Aminofenil)-1-piperazinil]fenolo

Descrizione:

4-[4-(4-Aminofenil)-1-piperazinil]fenolo, con il numero CAS 74853-08-0, è un composto organico caratterizzato dalla sua struttura complessa che include un gruppo fenolico e una porzione di piperazina. Questo composto appare tipicamente come un solido ed è solubile in solventi organici, con solubilità moderata in acqua a causa della presenza di regioni idrofobiche e idrofili nella sua struttura. Mostra proprietà associate sia alle ammine che ai fenoli, il che può influenzare la sua reattività e interazioni nei sistemi biologici. La presenza del gruppo amminico suggerisce potenziale per legami idrogeno e reattività in varie reazioni chimiche, rendendolo di interesse nella chimica medicinale, in particolare nello sviluppo di farmaci. Le sue caratteristiche strutturali possono anche contribuire alla sua attività biologica, influenzando potenzialmente i sistemi di neurotrasmettitori o altre vie fisiologiche. I dati di sicurezza devono essere consultati per le linee guida di manipolazione ed esposizione, come per qualsiasi sostanza chimica.

Formula: C₁₆H₁₉N₃O

InChI: InChI=1S/C16H19N3O/c17-13-1-3-14(4-2-13)18-9-11-19(12-10-18)15-5-7-16(20)8-6-15/h1-8,20H,9-12,17H2

InChI key: InChIKey=WZIJMPVPOMTRNM-UHFFFAOYSA-N

SMILES: NC1=CC=C(N2CCN(CC2)C3=CC=C(O)C=C3)C=C1

Sinonimi:

• 4-(4-(4-Aminophenyl)Piperazin-1Yl)Phenol
• 4-(4-Aminophenyl)-1-(4-hydroxyphenyl) piperazine
• 4-[4-(4-Aminophenyl)-1-piperazinyl]phenol
• 4-[4-(4-Aminophenyl)piperazin-1-yl]benzolol
• 4-[4-(4-Aminophenyl)piperazin-1-yl]phenol
• Phenol, 4-[4-(4-Aminophenyl)-1-Piperazinyl]-
• Posaconazole Intermediate
• 1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine
• 1-(4-Nitrophenyl)-4-(4-hydroxyphenyl)piperazine

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS: 74853-08-0

Formula: C₁₆H₁₉N₃O

Purezza: 98%

Colore e forma: Solid

Peso molecolare: 269.3416

Ref: IN-DA008OTL

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS: 74853-08-0

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

Purezza: 98%

Peso molecolare: 269.34g/mol

Ref: 54-OR80133

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS: 74853-08-0

Purezza: 95.0%

Colore e forma: Solid

Peso molecolare: 269.3479919433594

Ref: 10-F212508

4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol

Prodotto controllato

CAS: 74853-08-0

Applications 4-[4-(4-Aminophenyl)-1-piperazinyl]phendiamineol is an intermediate of Posaconazole (P689600), which is orally active antifungal triazole.
References Cacciapuoti, A., et al.: Antimicrob. Agents Chemother., 44, 2017 (2000); Herbrecht, R., et al.: Int. J. Clin. Pract., 58, 612 (2004); Panackal, A., et al.: J. Clin. Microbiol., 44, 1740 (2006); Yan, X., et al.: Guangzhou Huagong, 41, 107 (2013);

Formula: C₁₆H₁₉N₃O

Colore e forma: Neat

Peso molecolare: 269.34

Ref: TR-A626090

Posaconazole Impurity 73

CAS: 74853-08-0

Formula: C₁₆H₁₉N₃O

Peso molecolare: 269.35

Ref: ST-EA-CP-P24065

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS: 74853-08-0

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine (1APHP) is a potential antiviral drug. It has been shown to bind to viral proteins and inhibit the release of viral particles. 1APHP binds to the active site of the helicase-primase enzyme that is necessary for viral replication, thereby preventing the synthesis of new DNA. 1APHP has been shown to exhibit anticancer activity in animal cancer cell lines and in bone cancer cells. 1APHP inhibits cancer cell growth by inducing apoptosis via a multistep process that includes inhibition of protein synthesis, induction of endoplasmic reticulum stress, and activation of caspases. The crystal structure and diffraction data have been elucidated using X-ray crystallography and X-ray diffraction respectively. Molecular docking studies were performed with HIV protease as a model system to study possible interactions between 1APHP and HIV protease.

Formula: C₁₆H₁₉N₃O

Purezza: Min. 95%

Peso molecolare: 269.34 g/mol

Ref: 3D-FH00585

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine

CAS: 74853-08-0

1-(4-Aminophenyl)-4-(4-hydroxyphenyl)piperazine is a useful organic compound for research related to life sciences. The catalog number is T65582 and the CAS number is 74853-08-0.

Formula: C₁₆H₁₉N₃O

Colore e forma: Solid

Peso molecolare: 269.348

Ref: TM-T65582