CAS 7518-17-4

4-Epianidrotetraciclina

Descrizione:

4-Epianidrotetraciclina è un derivato semisintetico della tetraciclina, un antibiotico ad ampio spettro. È caratterizzato dalla sua struttura tetraciclica, che è essenziale per la sua attività biologica. Questo composto presenta proprietà antibatteriche inibendo la sintesi proteica nei batteri, rendendolo efficace contro una varietà di organismi gram-positivi e gram-negativi. La formula chimica di 4-Epianidrotetraciclina include più gruppi funzionali, contribuendo alla sua solubilità e reattività. Viene tipicamente somministrato nella sua forma di sale cloridrico per migliorare stabilità e biodisponibilità. La sostanza è nota per la sua stabilità moderata a alta in condizioni acide, ma può degradarsi in ambienti alcalini. Inoltre, è stata studiata per le sue potenziali applicazioni oltre l'uso antibiotico, comprese le proprietà anti-infiammatorie e anticancro. Come altre tetracicline, può causare effetti collaterali come disturbi gastrointestinali e fotosensibilità. Le condizioni di manipolazione e stoccaggio adeguate sono essenziali per mantenere la sua efficacia e il profilo di sicurezza.

Formula: C₂₂H₂₂N₂O₇

InChI: InChI=1S/C22H22N2O7/c1-8-9-5-4-6-12(25)13(9)17(26)14-10(8)7-11-16(24(2)3)18(27)15(21(23)30)20(29)22(11,31)19(14)28/h4-6,11,16,25-27,31H,7H2,1-3H3,(H2,23,30)/t11-,16+,22-/m0/s1

InChI key: InChIKey=CXCVEERYMJZMMM-WPINSWFRSA-N

SMILES: O[C@]12[C@]([C@@H](N(C)C)C(O)=C(C(N)=O)C1=O)(CC=3C(C2=O)=C(O)C=4C(C3C)=CC=CC4O)[H]

Sinonimi:

• (4R)-Anhydrotetracycline
• (4R,4aS,12aS)-4-(Dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide
• (4R,4aS,12aS)-4-(Dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-1,4,4a,5,12,12a-hexahydrotetracene-2-carboxamide
• (4R,4aS,12aS)-4-(dimethylamino)-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-4a,5-dihydro-4H-tetracene-2-carboxamide
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, 4-epimer
• 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, [4R-(4α,4aβ,12aβ)]-
• 2-naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,12,12a-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-, (4R,4aS,12aS)-
• 4-Epianhydrotetracycline
• 4-epi-5a,6-Anhydrotetracycline
• 4-epi-Anhydrotetracycline
• Anhydro-4-epitetracycline
• Anhydroepitetracycline
• Epianhydrotetracycline

Tetracycline EP Impurity D (Chlortetracycline EP Impurity I, Lymecycline EP Impurity D, 4-Epianhydrotetracycline)

CAS: 7518-17-4

Formula: C₂₂H₂₂N₂O₇

Peso molecolare: 426.43

Ref: 4Z-T-404

4-Epianhydrotetracycline

CAS: 7518-17-4

4-Epianhydrotetracycline is a chemical compound that is a derivative of tetracycline, a well-known antibiotic. It is primarily a byproduct arising from the chemical degradation of tetracycline antibiotics, occurring under acidic or basic conditions. The source of this compound is the structural transformation of tetracycline, resulting in an altered molecular configuration.

Formula: C₂₂H₂₂N₂O₇

Purezza: Min. 95%

Peso molecolare: 426.4 g/mol

Ref: 3D-HAA51817

Lymecycline EP Impurity D

CAS: 7518-17-4

Formula: C₂₂H₂₂N₂O₇

Peso molecolare: 426.42

Ref: ST-EA-CP-L64004

4-Epianhydrotetracycline hydrochloride hydrate

CAS: 4465-65-0, 7518-17-4

4-Epianhydrotetracycline hydrochloride hydrate is a chemical compound that inhibits the activation of protein kinase C (PKC) and blocks the apoptosis pathway. It has been shown to induce apoptosis in prostate cancer cells and also inhibits the proliferation of human microvessel endothelial cells. 4-Epianhydrotetracycline hydrochloride hydrate is stable in both human serum and wastewater, which makes it an ideal drug for treating many types of cancers. It is also used in pharmaceutical drugs as a cytochalasin, which are used to treat angina pectoris by reducing oxygen uptake by erythrocytes, thereby inhibiting oxidative phosphorylation. 4-Epianhydrotetracycline hydrochloride hydrate prevents mitochondrial cytochrome c release, thus blocking the apoptotic pathway in cells. This chemical compound may act as a regulatory molecule that affects energy metabolism and epidermal growth factor (EGF)

Formula: C₂₂H₂₃ClN₂O₇

Purezza: Min. 95%

Peso molecolare: 462.88 g/mol

Ref: 3D-FE22716