CAS 75738-58-8

Cloridrato di cefmenoxima

Descrizione:

Cloridrato di cefmenoxima è un antibiotico cefalosporinico semisintetico che appartiene alla classe degli antibiotici beta-lattamici. È utilizzato principalmente per il trattamento di varie infezioni batteriche grazie alla sua attività ad ampio spettro contro batteri Gram-positivi e Gram-negativi. Il composto mostra stabilità contro alcune beta-lattamasi, il che ne migliora l'efficacia contro ceppi resistenti. Cloridrato di cefmenoxima viene tipicamente somministrato per iniezione ed è noto per le sue favorevoli proprietà farmacocinetiche, inclusa una buona penetrazione nei tessuti e una vita media relativamente lunga, che consente una somministrazione meno frequente. La sostanza è caratterizzata dalla sua capacità di inibire la sintesi della parete cellulare batterica, portando alla lisi cellulare e alla morte. Gli effetti collaterali comuni possono includere disturbi gastrointestinali, reazioni allergiche e potenziali impatti sulla funzione renale. Come con altri antibiotici, è essenziale utilizzare Cloridrato di cefmenoxima in modo giudizioso per ridurre al minimo il rischio di sviluppare resistenza agli antibiotici. Sono necessarie condizioni di stoccaggio adeguate per mantenere la sua stabilità ed efficacia, richiedendo tipicamente protezione dalla luce e dall'umidità.

Formula: C₃₂H₃₅ClN₁₈O₁₀S₆

InChI: InChI=1/2C16H17N9O5S3.ClH/c2*1-24-16(20-22-23-24)33-4-6-3-31-13-9(12(27)25(13)10(6)14(28)29)19-11(26)8(21-30-2)7-5-32-15(17)18-7;/h2*5,9,13H,3-4H2,1-2H3,(H2,17,18)(H,19,26)(H,28,29);1H/b2*21-8-;/t2*9-,13-;/m11./s1

InChI key: InChIKey=HZYJYGJIOCXOTH-FAIYLGIWSA-N

SMILES: C(O)(=O)C=1N2[C@@]([C@H](NC(/C(=N\OC)/C3=CSC(N)=N3)=O)C2=O)(SCC1CSC=4N(C)N=NN4)[H].Cl

Sinonimi:

• (6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(1-methyl-1H-tetrazol-5-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride (2:1)
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]-
• 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-
• 7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride
• 7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride
• Abbott 50192
• Bestcall
• Bestron
• Cefmax
• Cefmenoxime Hcl
• Cefmenoxime hemihydrochloride
• Cefmenoxime.1.5 HCl
• Cemix
• SCE-1365(free acid)
• Tacef
• Cefmenoxime hydrochloride
• Cefmenoxime  Hydrochloride
• CefMenoxiMe SodiuM
• ab50912hemihydrochloride
• hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o
• CEFMENOXIME HEMIHYDROCHLORIDE;SCE-1365 HEMIHYDROCHLORIDE
• 7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
• cefmenoximehemihydrochloride
• CefMenoxiMe HCL Sterile (pure)
• Hydrochloride (syn-isomer)
• )(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox
• SCE-1365 hemihydrochloride
• (6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid HeMihydrochloride
• (6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride(2:1)
• 2Cefmenoxime·Hydrochloride
• Cefmenoxime Hydrochloride (350 mg)
• sce1365hydrochloride
• Cefmenoxime hydrochloride USP/EP/BP
• (6R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid·0.5hydrochloride

Cefmenoxime hydrochloride

CAS: 75738-58-8

Cefmenoxime hydrochloride: cephalosporin antibiotic, IV/IM, targets gram-positive/negative bacteria, beta-lactamase resistant, effective, low side effects.

Formula: C₃₂H₃₅ClN₁₈O₁₀S₆

Purezza: 98.02% - 98.41%

Colore e forma: Solid

Peso molecolare: 1059.58

Ref: TM-T1190

Cefmenoxime hydrochloride

CAS: 75738-58-8

Cefmenoxime hydrochloride

Purezza: ≥98%

Peso molecolare: 1059.58g/mol

Ref: 54-BUP14928

Cefmenoxime hydrochloride

CAS: 75738-58-8

Formula: C₁₆H₁₈ClN₉O₅S₃

Peso molecolare: 548.02

Ref: 7W-GA5301

Cefmenoxime HCl

CAS: 75738-58-8

Formula: C₁₆H₁₇N₉O₅S₃·5HCl

Peso molecolare: 511.55 0.5 36.46

Ref: 4Z-C-312001

Cefmenoxime Hydrochloride

Prodotto controllato

CAS: 75738-58-8

Applications A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis.
References Yakota, N. et al.: Jpn. J. Antibiot., 48, 602 (1995); Fukuda, M. et al.: Jpn. J. Ophthamol., 46, 384 (2002);

Formula: C₁₆H₁₇N₉O₅S₃·ClH

Colore e forma: Neat

Peso molecolare: 1059.58

Ref: TR-C242835

Cefmenoxime hydrochloride

CAS: 75738-58-8

Cefmenoxime hydrochloride is a third-generation cephalosporin antibiotic with action on bacterial cell wall synthesis and is used for treating gynecological and obstetric infections.

Formula: C₁₆H₁₇N₉O₅S₃HCl

Purezza: Min. 95%

Colore e forma: White Powder

Peso molecolare: 529.79 g/mol

Ref: 3D-FC19858